Synvisc-One and Nausea: What Users Say

• Bea...
• Taken for less than 1 month
• October 6, 2019

For Osteoarthritis "I had a Synvisc-One injection in each knee. My right knee had no problems. My left knee filled with fluid after 24 hours. I had nausea, chills, pain, and a grapefruit-sized knee. I had it drained, and it instantly felt better. I was able to walk again. It has filled up again, not as painful, but still can't sleep due to pain. Waiting for lab results on the fluid."

• San...
• Taken for less than 1 month
• November 11, 2019

For Osteoarthritis "Had one Synvisc-One injection a week ago in a knee that before the injection only hurt when walking up or down stairs. Immediately, I had a stuffed nose, swollen tongue, never had headaches, but now nausea and headaches. Worst of all, my leg and veins hurt so badly all the time that I haven't had a quality day for a week and haven't slept because of the pain because nothing helps. Tried pain rubs, creams, natural pain meds, and no relief. I avoided stairs for five years and will gladly do it again if I can get this terrible experience out of my body. I give this a one, and from the comments given, I should have never taken this in the first place. Dishonest doctor!!!"

• Tra...
• Taken for 2 to 5 years
• August 4, 2018

For Osteoarthritis "Had first round of shots in left and right knees last year, which lasted 9 months. Due to my limited mobility and obesity, Doc recommended I do low-impact water aerobics and NO MORE pavement walking. The shots worked with 80% relief and hardly any sharp pains or clicking, only once in a while if I turned funny. The knees would 'catch,' so this med was great! Lost 38 pounds in 9 months, now walking on trails again and able to do slow flow and fundamental yoga, so have moved up from just swimming! Ready to lose the last 60 pounds! Had second shots today, and my legs felt very fatigued walking a mild 20-minute stroll tonight. I have a headache and a little nausea, but not bad. Doc's advice was to get as light and lean as possible in a healthy weight range. I look forward to it - that's my plan. Best of luck and light to us all!"

• Daw...
• May 29, 2018

For Osteoarthritis "On 3/24/18, I had Synvisc One in both knees at the same time. I got a bit flushed, nauseous, and like I would faint right after. Used a wheelchair to get to the car as my legs were very stiff and heavy feeling afterward. Had a spray cool numbing agent before shots, neither were very painful. Got shots on the outside of both knees, which the doctor said was usually less painful. One knee got about 90% relief the first week, the other only about 30%. Then I fell on both knees down a concrete step 14 days after injections, which didn't help my situation. I waited for 5 weeks after injections, icing frequently, mostly for the fall issues. I now had about 40% and 75% relief, so on 5/1/18, I went for an appointment, and they suggested a cortisone shot on top of the Synvisc One injection, and I had some more relief after that, even though cortisone shots had never helped me before. I got it in both knees, which hurt way more than the initial injection. But it worked. I am now about 85% and 90% relief!!! On 5/28/18."

• Bad...
• Taken for less than 1 month
• July 21, 2021

For Osteoarthritis "I had both my knees injections done at the same time. The next day, both knees were filled with fluid and couldn’t walk. I was sick and nauseous. No fever. I gave it a week to see if the swelling would go down, but no change. I had to use crutches. I contacted my Dr., and she had me come to her office immediately for I had a bad reaction. She drained both knees and inserted cortisone. The next day I was back to normal and could walk. I wouldn’t recommend this."