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Estarylla and Depression: What Users Say

Depression: mentioned by 146 users (27.5%)

Based on user experiences from 530 Estarylla reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

depression 27.5%
nausea 25.5%
anxiety 23.4%
mood swings 22.6%
acne 19.6%
bleeding 14.2%
weight gain 14.0%
headaches 11.3%
cramps 10.8%
spotting 8.3%

Reviews for Estarylla

Commonly mentioned side effects
  • Anonymous
  • Taken for 5 to 10 years
  • December 15, 2020

For Birth Control "DO NOT TAKE THIS! I have been trying to figure out what was wrong with me for over a year. Never once did it occur that it was the birth control I am taking, but I finally came to the realization. I never had these issues prior to taking this pill. I have developed anxiety, depression, my joy for life is gone, I have absolutely no sex drive, it's like there is a dark cloud over me, I am unmotivated and tired, the list goes on. I'll take acne and painful periods any day over what I have experienced over these last few years because of this pill. I wish I had known this before I started. I was young and had no clue. Was very uninformed. I hope this helps someone else. Do not do it. It is not worth it at all!"

1 / 10
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  • Ver...
  • Taken for 1 to 6 months
  • April 9, 2019

For Birth Control "DON'T READ THE REVIEWS!!!!! The pill works so differently for everyone’s body. I was on Loestrin Fe for around 6 months before I started Estarylla. On the Loestrin, I experienced awful depression that I didn’t even know was possible from birth control. In the first week of starting Estarylla, I felt 100 times better and still feel way happier. While on my first pill, I read the reviews on this website and started sobbing my eyes out, freaking out that Estarylla was going to be the death of me. The only bad thing I've experienced on this medication is extremely heavy irregular bleeding, but I realize it’s still the first month, so it should get better. Birth control works WAY differently on everyone’s body, so don’t let these reviews freak you out!!!!"

9 / 10
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  • Ell...
  • February 4, 2021

For Birth Control "Reading these other reviews makes me question my experience with this birth control because I have anxiety and depression. However, I have struggled with this all my life, and I can't say for sure that Estarylla has impacted these things for me. I've taken this birth control for over two years, and I have a very high sex drive along with clear skin! My experience has been overwhelmingly positive, but I wish there was more education about the possible physical and mental side effects of these medications."

9 / 10
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41 Report

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  • Cal...
  • Taken for 2 to 5 years
  • December 31, 2020

For Birth Control "I’ve been on this pill, Estarylla, for 3 years. It was the generic form, Ortho Tri-Cyclen. This pill has caused me severe depression, brain fog, a feeling like a heavy darkness over my life with suicidal thoughts, anger and aggression, and migraine headaches. I’ve had severe anxiety, constipation, and stomach pain. When I’m off for the 7-day placebo tablets, I feel the best, but then I start the new pack Sunday, and the cycle starts again until the end of the pack. This product should be discontinued. I did clear up my skin and prevent pregnancy, but it hasn’t been worth it."

1 / 10
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30 Report
  • CV ...
  • Taken for less than 1 month
  • May 13, 2021

For Birth Control "Like many of the other ladies, I was on Femynor, and my pharmacy switched me to this because they were out. I noticed the change almost immediately, by day 4, I threw the pack away. My husband noticed that I was easily angered, was crying about everything, and seemed depressed. I had tried them about 2 years ago and had the same problem. Everybody is different, but I'm sharing my experience because the pharmacist made it seem as if I was crazy. You know your body!"

1 / 10
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24 Report

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  • Kka...
  • Taken for 1 to 6 months
  • June 16, 2020

For Abnormal Uterine Bleeding "I’ve been on birth control pills for the last 10 years and never once experienced breakthrough bleeding until switching to Estarylla 3 months ago (I had been using Spintec for the majority). I’m now on my 9th week of nonstop bleeding. My mood swings and depression haven’t been this bad in years. I’m going to my doctor next week to talk about getting a different kind of birth control altogether (probably an IUD) because this experience has been rather traumatic for both my body and mental health. Please stay away from this brand of birth control pills."

1 / 10
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  • Cha...
  • Taken for 1 to 6 months
  • January 13, 2019

For Birth Control "I’ve never left a review for anything before. Not a movie, nor a restaurant, nothing. This birth control is THE WORST. After being on Mononessa for a couple of years and having no issues, Walgreens changed the prescription to Sprintec (also no problems) and then to this Estarylla poison. I’m 18, almost 19, an extremely happy, healthy, active, hardworking person. Estarylla has completely demolished my self-esteem, leaving me in a weird, depressed, anxiety-ridden state for the one and a half months I’ve been taking it. I’ve been feeling like I’m in this weird, dreamlike state for the past few weeks and was so relieved to hear that other people on this medication have felt the same way. I’ve not had the motivation to get work done or socialize due to the extreme mood swings, depression, and fatigue that Estarylla causes. Please, please don’t take Estarylla. For the sake of your mental and physical health."

1 / 10
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33 Report
  • Sha...
  • Taken for 6 months to 1 year
  • December 27, 2019

For Birth Control "I took Mononessa for years and never had a problem. One month, my pharmacy gave me Estarylla, and I immediately noticed a difference. When I called my doctor to let her know I didn't want the Estarylla and wanted the Mononessa back, like I've always had, they just acted like I didn't know what I was talking about, since it is 'basically the same drug.' Once Mononessa was taken off the market, my doctor started prescribing me Estarylla on the regular. It does what it needs to when it comes to birth control, but the side effects are absolutely awful. I have major nausea, headaches, and depression when taking this birth control. I also found it had heavily decreased my sex drive and has given me severe mood swings. I quit taking the drug for a month or two, and all symptoms went away. I don't think I'll ever take it again after I finish this month."

1 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • September 16, 2020

For Birth Control "I really didn't like this Estarylla birth control. I was initially on Femynor (LOVE), but one day I picked up my prescription and I was given Estarylla. I called my gynecologist, and the nurse said it was a generic brand and shouldn’t affect me much, but it was AWFUL. I was on it for two months. I probably didn’t give it time to settle in, but Femynor never gave me this many issues so early on. I was very depressed, unmotivated, broke out, tired, experienced a lot of anxiety attacks, and super nauseated. I know everyone is different, but for me, it was the worst. My period went rather smoothly, I will say, but other than that, AWFUL! I recommend Femynor 10/10."

2 / 10
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22 Report
  • Hap...
  • Taken for 1 to 6 months
  • March 20, 2019

For Birth Control "Everybody, EVERYBODY reacts differently to medications, especially birth control! I read all of these negative comments and popped the first pill, and I’m still breathing, y’all! I’m on week 3, and my face is SO CLEAR, and it’s literally like glowing, lol. I suffer from mild depression, and this doesn’t touch it. Not pregnant, didn’t gain weight, sleeping okay, lol. I love this pill. You never know how you will react to a medication until you try it (with the permission of your doctor). If you don’t like it-great, then be responsible, throw it out, and use a backup birth control like condoms and spermicide until you get into the doctor’s office. :)"

10 / 10
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20 Report
  • BMS...
  • Taken for 1 to 6 months
  • October 5, 2020

For Abnormal Uterine Bleeding "Well, I am really glad I came on here to see I wasn't the only one with the experiences I have been having. So, I decided to add my comments in as I was trying to use Estarylla for abnormal bleeding. I initially would pretty much bleed weeks out of the month, granted some weeks lighter than others, so the doctor recommended this brand. It was not effective for my problem (actually bleeding more), and the side effects it gave me scared me. I became severely depressed, crazy mood swings, sex drive dived down to zero, and weight gain. I am 42 years old, unsure if age is a factor with this birth control pill but...."

1 / 10
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  • Meg...
  • Taken for 1 to 6 months
  • November 27, 2018

For Abnormal Uterine Bleeding "This was the worst birth control I have ever taken. I was previously on MonoNessa, which I loved, but then was switched to this generic. I never had an issue with abnormal bleeding (been on MonoNessa about 6 years) and am on an SSRI, so my mood is pretty stabilized. However, about 5 months into this generic, I had the worst month of my life. I bled clots of blood for a month straight and had to go to the doctor. Additionally, I felt so depressed all the time and had suicidal thoughts almost daily, even when taking my SSRI. I recently switched to a new birth control and feel 100X better. This birth control was awful. Would not recommend for anyone."

1 / 10
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15 Report
  • cha...
  • Taken for 1 to 6 months
  • December 16, 2020

For Birth Control "Estarylla is the first brand of birth control I tried, and I'm finally changing my BC pills now. I hate the way these pills made me feel. At first, I didn't realize what was going on with me, I was thinking I'm going crazy in my own head. Severe mood swings, I felt depressed all the time. My anxiety got WAY worse. I'm finally getting off these pills. The good part is my period got regular, and my cramps are not as bad, but I can't do Estarylla anymore. I do not recommend this brand to any girl. If you want to stay happy and enjoy your life."

1 / 10
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  • Crc...
  • Taken for less than 1 month
  • May 27, 2020

For Ovarian Cysts "I hate to write a review this awful, but I have to. People should know how life-altering this pill is. I started taking Estarylla a week ago and had to throw them in the trash. If you have, or have ever had, any bouts with anxiety or depression, do not even look at this pill. I don’t remember a time I have felt so low and lethargic, and then let’s not forget the cystic acne that popped up on my jaw and chin. If it works for you, that’s great, but it has torn me up!"

1 / 10
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12 Report
  • Mya...
  • Taken for 1 to 6 months
  • August 20, 2019

For Birth Control "I have only been using Estarylla for a month now, and within this month, it has been the WORST! It has dried my skin, especially my hands and around my mouth. I have been spotting this whole time, and it has caused BAD mood swings. I have gone into deep depression, had really dark thoughts. My attitude has been horrible, especially my emotions. I'll cry after having a moment of dark thoughts, and it's just a cycle. I have lost my appetite. The medicine has given me a yeast infection as well. Everybody's body is different, but I do not recommend this medication."

1 / 10
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  • PCO...
  • Taken for 5 to 10 years
  • February 20, 2019

For Ovarian Cysts "I was prescribed this form of BC to help treat my PCOS and irregular periods. I've been taking Estarylla (previously Mononessa) for about 10 years now. To be honest, I think it works very well. My periods are light flow, light cramping, and always on time. My acne has always been mild and usually only on my face. I do experience some depression and anxiety, but I figure that's just me. It is important to take this at the same time every day for best results. I also recommend drinking plenty of water (because it's great for your body! :)"

8 / 10
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  • Jan...
  • Taken for 1 to 6 months
  • November 16, 2020

For Abnormal Uterine Bleeding "I really don't like this pill. I feel sick all the time. Headaches, blurred vision, motion sickness, hot flashes, and depression. My vagina is always dry and itchy. I am so sick to the point of leaving work and lying in bed all day. The weight gain is horrible. I was on it for period control."

1 / 10
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8 Report
  • Kay...
  • Taken for 1 to 2 years
  • January 7, 2020

For Birth Control "I’ve been on this pill for about a year now. I stopped taking it for a while and noticed that my mood had lifted and I was overall a happier person. I do think that all birth control pills can make you feel sad and depressed, but I think that Estarylla really amplified those feelings. I didn’t find it to clear up my acne, and I did gain weight. I would say this pill is average, but I’m hoping to find something better."

4 / 10
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9 Report
  • Sta...
  • Taken for 1 to 6 months
  • January 29, 2020

For Birth Control "Definitely a horrible birth control. Started it 2 months ago, and I have put on weight, irregular spotting in between periods. Most of all, my mood swings have been so bad. Makes me feel bipolar. I cry over everything and get so mad. Even feel depressed. Was on Tri-Previfem for years and didn’t have any side effects. Switching back next week. Pharmacists claim they’re all the same ingredients included, but I disagree."

1 / 10
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11 Report
  • Ell...
  • Taken for 1 to 2 years
  • June 2, 2016

For Birth Control "I had a negative experience with this pill. I took it for a year, and while it effectively served the purpose of preventing pregnancy, that's the only positive thing I have to say about it. I experienced side effects of depression and suicidal thoughts, anxiety and a panic attack, frequent breakthrough bleeding, breast tenderness, and weight gain of 10 pounds. I am not prone to weight gain and haven't had this issue or emotional issues with the other 2 birth control pills I've taken. I would advise extreme caution in proceeding with taking this pill. I should have read the reviews before I took it."

2 / 10
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  • Aan...
  • Taken for 1 to 6 months
  • November 22, 2019

For Birth Control "I started this birth control, Estarylla, after I got my IUD out. I hated the IUD, so after 2 years, I got it removed. I wanted a birth control that helped with acne because I have PCOS, and with that comes stupid hormonal acne. :( I am on month 3 of Estarylla, and I think I’m starting to hate it. The first 2 months were good, it actually helped my acne. Now, on my 2nd week of the pack, my chin broke out so bad! My boobs are sore, and I’m super depressed. I don’t take any other meds, so I know it has to be this birth control. I also get nauseous. Honestly, I think the side effects outweigh the benefits! Everyone’s different, but for myself, I do not recommend this med."

3 / 10
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8 Report
  • Anonymous
  • July 26, 2019

For Abnormal Uterine Bleeding "I was a little excited to say the least but nervous since I haven’t been on any medications since my tubal ligation 6 years prior. Within the first few weeks, I was already bleeding. I bled for 9 weeks straight. It was miserable, and then if to make things worse, I wanted to take out everyone around me for about 5 weeks. I had extreme anger issues, depression, my skin was breaking out. I talked to my doctor many times and was told to give it a little time to see how I adjusted. After 6 months, I decided I couldn’t take it anymore. I would have times that were okay, but I often felt like rubbish on this pill. The last straw was when I started a new packet of pills. I was fine the first week, started bleeding mid-2nd week, and by the third week, I was passing large blood clots for days, and then I got my period the 4th week. This pill isn’t for me, and now I’m starting something new. Hoping for better results!!"

3 / 10
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  • val...
  • Taken for 6 months to 1 year
  • May 7, 2021

For Birth Control "Wow, these reviews are scary. I’ve been taking this birth control for about 6-7 months, and it never affected me that bad. I will admit the first few months you feel a little dull, but that’s just because of new hormones in your body. Hair never fell out or anything, instead, it grew crazy long, at least 7 inches. It never affected me in a negative way or made me gain weight, it actually made me lose a few 3 pounds, and if anything, made me more mature. At the end of the day, birth control, no matter what brand, affects everybody in way different ways, but for me, this didn’t affect me terribly or anything, if anything, I was doing amazing on it."

10 / 10
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7 Report
  • sdc...
  • Taken for less than 1 month
  • June 6, 2019

For Abnormal Uterine Bleeding "This was my first time getting on the pill. My doctor put me on Estarylla, and everything just went downhill from there. I was aware of the side effects, granted this is my first time being on the pill. But I have never felt so awful in my life. By the third week, I hit a wall with depression, so uncomfortably bloated, tons of nausea that never went away and abdominal pains. I finally called and told them what’s up, and they are wanting to switch me to Sprintec. Everyone’s bodies are different, but Estarylla made me feel the lowest of lows."

2 / 10
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9 Report
  • Mia...
  • August 12, 2016

For Birth Control "I've taken this pill for one month, and so far the first week I was absolutely fine. Then the second week I started to be a little bit down, and then the third week I literally cried at least three times a day. I became very tired, and I had no motivation to do anything. I slept 12-14 hours, or I didn't sleep at all. I've been angry and irritable over the slightest things. I am 15, and normally I'm a very bubbly, positive, energetic person, and I don't even feel like me anymore. I've been really depressed. I'm very highly disappointed with this pill. It was the first birth control I've ever used. I used it to regulate my period, so far it's done its job I suppose, however, the side effects and mood that I've been in are most certainly not worth it. Don't take it."

1 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.