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Estarylla Alternatives Compared

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Estarylla Mirena Lo Loestrin Fe
View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Estarylla (ethinyl estradiol / norgestimate) Mirena (levonorgestrel) Lo Loestrin Fe (ethinyl estradiol / norethindrone)
Prescription only

Prescribed for Abnormal Uterine Bleeding, Acne, Endometriosis, Birth Control, Gonadotropin Inhibition. May also be prescribed off label for Ovarian Cysts.

Prescription only

Prescribed for Abnormal Uterine Bleeding, Birth Control. Mirena may also be used for purposes not listed in this medication guide.

Prescription only

Prescribed for Birth Control. Lo Loestrin Fe may also be used for purposes not listed in this medication guide.

More about Estarylla (ethinyl estradiol / norgestimate) More about Mirena (levonorgestrel) More about Lo Loestrin Fe (ethinyl estradiol / norethindrone)
Generic Status

Lower-cost generic is available

Lower-cost generic is available

Lower-cost generic is available
Ratings & Reviews

Estarylla has an average rating of 3.6 out of 10 from a total of 483 ratings on Drugs.com. 22% of reviewers reported a positive effect, while 66% reported a negative effect.

Mirena has an average rating of 6.1 out of 10 from a total of 2487 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 32% reported a negative effect.

Lo Loestrin Fe has an average rating of 5.7 out of 10 from a total of 1473 ratings on Drugs.com. 43% of reviewers reported a positive effect, while 37% reported a negative effect.

View all 483 reviews

View all 2487 reviews

View all 1473 reviews

Drug Class
Side Effects

See also: Estarylla side effects in more detail.

See also: Mirena side effects in more detail.

See also: Lo Loestrin Fe side effects in more detail.
Pricing and Coupons * Prices are without insurance
Quantity 84 each
Dosage 35 mcg-0.25 mg
Per Unit* $0.48
Cost* $40.16

View all Estarylla prices and generic prices

Quantity 1 device
Dosage 52 mg
Per Unit* $1,114.35
Cost* $1,114.35

View all Mirena prices and generic prices

Quantity 140 each
Dosage with iron biphasic 10 mcg-1 mg
Per Unit* $6.19
Cost* $867.17

View all Lo Loestrin Fe prices and generic prices

Get free Discount Card

Get free Discount Card

Get free Discount Card

Dosage Form(s) Available
  • Oral tablet
  • Intrauterine device
  • Oral tablet
Brand Names
Other ethinyl estradiol / norgestimate brands include: Femynor, Mili, Mono-Linyah, Nymyo, Previfem, Sprintec, Tri Femynor, Tri-Estarylla, Tri-Linyah, Tri-Lo-Estarylla, Tri-Lo-Marzia, Tri-Lo-Mili, Tri-Lo-Sprintec, Tri-Mili, Tri-Nymyo, Tri-Previfem, Tri-Sprintec, Tri-VyLibra, Tri-Vylibra Lo, VyLibra View more Other levonorgestrel brands include: Aftera, AfterPill, AfterPlan, Athentia Next, BionaFem, EContra EZ, EContra One-Step, Fallback Solo, Kyleena, Liletta, Morning After, My Choice, My Way, New Day, Next Choice One Dose, Opcicon One-Step, Option 2, Plan B One-Step, PostDay One-Step, Preventeza, React, Skyla, Take Action View more Other ethinyl estradiol / norethindrone brands include: Alyacen 1/35, Alyacen 7/7/7, Aranelle, Aurovela 1.5/30, Aurovela 1/20, Aurovela 24 Fe, Aurovela Fe 1.5/30, Aurovela Fe 1/20, Balziva, Blisovi 24 Fe, Blisovi Fe 1.5/30, Blisovi Fe 1/20, Brevicon, Briellyn, Chabelina Fe, Charlotte 24 Fe, Cyclafem 0.5/35, Cyclafem 1/35, Cyclafem 7/7/7, Cyonanz, Dasetta, Dasetta 1/35, Dasetta 7/7/7, Estrostep Fe, Femcon Fe, femhrt, Finzala, Fyavolv, Gemmily, Generess Fe, Gildagia, Gildess 1.5/30, Gildess 1/20, Gildess 24 Fe, Gildess Fe 1.5/30, Gildess Fe 1/20, Hailey 1.5/30, Hailey 24 Fe, Hailey Fe 1.5/30, Hailey Fe 1/20, Jinteli, Junel 1.5/30, Junel 1/20, Junel Fe 1.5/30, Junel Fe 1/20, Junel Fe 24, Kaitlib Fe, Larin 1.5/30, Larin 1/20, Larin 24 Fe, Larin Fe 1.5/30, Larin Fe 1/20, Layolis Fe, Leena, Leribane, Loestrin 21 1/20, Lomedia 24 Fe, Melodetta 24 Fe, Merzee, Mibelas 24 Fe, Microgestin 1.5/30, Microgestin 1/20, Microgestin Fe 1.5/30, Microgestin Fe 1/20, Minastrin 24 Fe, Necon 0.5/35, Necon 7/7/7, Nexesta Fe, Norinyl 1+35, Nortrel 0.5/35, Nortrel 1/35, Nortrel 7/7/7, Nylia 1/35, Nylia 7/7/7, Ortho-Novum 7/7/7, Philith, Pirmella 1/35, Pirmella 7/7/7, Tarina 24 Fe, Tarina Fe 1/20, Taysofy, Taytulla, Tilia Fe, Tri-Legest, Tri-Legest Fe, Vyfemla, Wera, Wymzya Fe, Zenchent, Zenchent Fe View more
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

N/A

45 hours

14 hours
CSA Schedule ** View glossary of terms
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
Pregnancy Category
X
Category X Not for use in pregnancy

See the full pregnancy warnings document.
X
Category X Not for use in pregnancy

See the full pregnancy warnings document.
X
Category X Not for use in pregnancy

See the full pregnancy warnings document.
Drug Interactions

A total of 431 drugs are known to interact with Estarylla:

  • 40 major drug interactions (112 brand and generic names)
  • 344 moderate drug interactions (1241 brand and generic names)
  • 47 minor drug interactions (515 brand and generic names)

A total of 229 drugs are known to interact with Mirena:

  • 35 major drug interactions (100 brand and generic names)
  • 180 moderate drug interactions (571 brand and generic names)
  • 14 minor drug interactions (66 brand and generic names)

A total of 434 drugs are known to interact with Lo Loestrin Fe:

  • 42 major drug interactions (117 brand and generic names)
  • 345 moderate drug interactions (1250 brand and generic names)
  • 47 minor drug interactions (515 brand and generic names)
Alcohol/Food/Lifestyle Interactions
  • Grapefruit juice may increase the blood levels of certain medications such as norgestimate. You... View more
  • Grapefruit juice may increase the blood levels of certain medications such as levonorgestrel. You... View more
  • Grapefruit juice may increase the blood levels of certain medications such as norethindrone. You... View more
Disease Interactions
First Approval Date

N/A

December 06, 2000

October 21, 2010
WADA Class View World Anti-Doping Agency classifications.

N/A

N/A

N/A
More Information
Patient resources

N/A
Professional Resources
Related Treatment Guide

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

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