Cenobamate and Fatigue: What Users Say

• Crs...
• February 1, 2021

For Seizures "I've been on every medication for seizures, have had my right temporal lobe removed, have a VNS, was doing the medical marijuana and not one thing has helped my seizures. As soon as I started taking this drug Xcopri, my seizures have stopped. Was having them every day and haven't had one in almost 3 months now, I just can't even believe it!!! The only downfall is the side effects. I first would just want to sleep all day long, had no energy at all, I couldn't think straight or remember things. I would talk and move very slowly, run into things like I was drunk! The sleeping has gotten better, I can stay awake all day now. I still have problems with memory and can't make decisions to save my life!!! I'm still very slow at things and can't walk straight. I'm at 100 mg 1x a day. I just finished taking my amitriptyline for sleep, and now I'm only taking Onfi in the morning. Still on Briviact, Lyrica, Lexapro, Buspar...but so far, so good!!!!"

• Anonymous
• Taken for 1 to 2 years
• October 24, 2022

For Seizures "My daughter failed 10 medicines and a VNS, and this is finally the thing that worked for her. She has not had a seizure in over a year. It does have side effects (fatigue, headache), but better than the others she has been on. Most importantly, this one has had no mental health side effects such as depression, anxiety, or anger."

• Ano...
• Taken for 6 months to 1 year
• June 7, 2025

For Seizures "Used in combination with lamotrigine. Been seizure-free for 7 months. Side effect: lack of energy and sleepiness (sleep 9-10 hrs a night plus a 30-60 min nap). NOTE: I cannot recommend this drug - only a doctor can."