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Acetaminophen / hydrocodone for Pain User Reviews (Page 4)

Brand names: Xodol Zyfrel

Acetaminophen / hydrocodone has an average rating of 6.2 out of 10 from a total of 715 reviews for the treatment of Pain. 52% of reviewers reported a positive experience, while 31% reported a negative experience.

Reviews for Acetaminophen / hydrocodone

  • Anonymous
  • Taken for less than 1 month
  • August 26, 2020

"I’ve been using hydrocodone for many years for chronic pain. This time I got a refill, I took one and it’s like I threw it in the trash. What’s up? I usually only need one a day but I have to take two in order to get some relief. I plan on complaining to the pharmacy."

1 / 10
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54 Report
  • Abriton
  • Taken for 2 to 5 years
  • August 26, 2019

"I have emailed Rite Aid where I fill my prescriptions for acetaminophen/hydrocodone for my osteoarthritis pain, letting them know about Mallinkrodt, which they recently switched to . I asked them if they have analysed these tablets. I told them of all the online complaints. I suggest we all complain to the customer service departments of our pharmacy headquarters. I have just heard back from Rite Aid. They have looked into this and said that they contacted Mallinckrodt who said that they recently outsourced this to another manufacturer! They have lodged a complaint which has to be looked into. They said the FDA will get involved. I urge everyone to COMPLAIN to your pharmacy head office and the FDA."

1 / 10
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64 Report
  • Melly
  • Taken for 5 to 10 years
  • November 24, 2019

"Please file complaints w the FDA about these scamming companies who are putting little to no hydrocodone into these generic acetaminophen / hydrocodone pills. I have been on Tris brand for 4 yrs last year they changed them they work like there is only half the actual amount of hydrocodone that they should be, just got newest refill and have been feeling withdrawal type feelings. The only way to stop them is to have the FDA investigate ,Unless this is all the government doing to torture us to death as they have been doing the last several years. This is absolutely sickening they're allowed to do this. I have tried every generic Norco 10mg none of them work this Tris brand used to sort of work but now they cut the hydrocodone again. It isn't just me having tolerance because last year when this happened had some old pills left and I took one I felt immediate relief. Same thing as this month. These companies need 2 go to prison 4 hurting us. Dr won't prescribe name brand and no pharmacy will fill name brand I have called many they all say they don't keep it in stock. What's the point of having name brand"

1 / 10
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61 Report
  • hurtin...
  • Taken for 5 to 10 years
  • October 22, 2022

"I am 64 female, with pain from fibromyalgia, bone spurs, herniated disc's, sciatica, degenerative disc disease spinal stenosis. I was always given Vicodin in the by the manufacturer Qualitest, after they sold to Endo, and then they sold to Par pharmaceuticals they started giving white ones. I complained many times about the efficacy of these white Norco generics and their inability to control my pain. Basically my Dr.'s and Pharmacist's did not believe me and basically said it was in my head, I can't believe that everyone has been saying and complaining about this and are getting the same rubbish as I did. I have an opinion that maybe the Bitartrate they are putting into the pills may have something to do with it. Just a thought."

1 / 10
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27 Report
  • AWM
  • Taken for 1 to 6 months
  • September 15, 2021

Vicodin (acetaminophen / hydrocodone) "Was just Rx’d 10/325 Vicodin from tris manufacturing. I recently found out I had several bulging disc and one herniated disc that pinched a nerve causing cervical radiculopathy . Worse pain I’ve ever experienced. I thought maybe I was given the wrong medication because I was still in agony several hours later. I don’t take these meds on a regular basis, in fact it’s been years for me. I thought I was crazy until I looked up these complaints. This terrifies me. If I end up needing surgery and this is what I get for pain relief I’m in big trouble. Something needs to be done."

1 / 10
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40 Report

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  • Pd-Off
  • Taken for 5 to 10 years
  • September 13, 2021

Norco (acetaminophen / hydrocodone) "Illegal is what is happening with Generic Norco! If they are claiming the generics are equal to Brand Norco, they are lying to your face. More people know what's going on and it's a secret to pretend they don't know. Its 100% rubbish. My pain level has continued to increase and my dosage has been increased to 6 a day with minimal relief? It seems doctors stopped asking if you have suicidal thoughts after initial exam. I believe the ones who seek out stronger drugs and overdose are tired of being joked around with by defective generic drugs. I'm not seeking out more pills or stronger drugs, I just don't want to be in pain and think about being in pain and how I'm supposed to live my life. A few years ago 1/2 pill to 2 pills would be enough depending on my day and how much strenuous activity I did that day or the day prior. Now 6 pills with no relief? Spinal Fusion, Disc Protrusion & RA until I die sooner rather than later. The people who responsibly use their meds should not be suffering"

1 / 10
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40 Report
  • Dink
  • Taken for 10 years or more
  • October 16, 2019

"The drug acetaminophen with hydrocodone is not being properly compounded. They are complete junk! Mallinckrodt needs to be shut down! I've been on pain meds for more than a decade and had success til their brand hit the market. I took one one day and felt so strange I called my daughter thinking I was dying. The next time I took it I didn't know I took it.. NO RELIEF WHAT SO EVER!!! PLEASE Y'ALL.. CONTACT THE FDA !!! BRING BACK THE BRANDS THAT HELP - WATSON AND THE YELLOW ONE I DON'T RECALL WHO MADE THOSE. .. BUT THIS BRAND IS CRUD!!"

1 / 10
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60 Report
  • Back...
  • December 13, 2018

Norco (acetaminophen / hydrocodone) "I found hydrocodone to be more effective then tramadol, gabapentin then they changed the drug over the years due to drug addicts abuse. Once the gold standard until people learned how to abuse it. Taken as prescribed it is effective with little or no side effects. However, it has deadly side effects when abused or mixed with other drugs. It was made with 660mg of acetaminophen which is dangerous if taking 10 pills to get high, you could do irreparable damage to your liver. So the amount of acetaminophen was limited to 325 in each pill. Some drug addicts figured out how to crush it up, prompting even more changes in the medication to prevent that abuse. Then some unethical doctors started over prescribing it to people who didn't need it, prompting more tighter restrictions by the government. Government has moved it from schedule III to schedule II drug further limiting its use, while states make Marijuana which is listed as a schedule I drug, legal for recreational use. stop abuse."

7 / 10
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68 Report
  • 28...
  • Taken for 10 years or more
  • February 26, 2022

Norco (acetaminophen / hydrocodone) "I have Fibromyagia/back pain/ whole upper body pain. Norco was the best nonaddictive but also effective pain reliever without taking the stronger more expensive oximorphone that was being pushed in pain clinics. The generics available now are very inferior to the yellow generic and name brand. Us old people are suffering because of someone's mess up and ALL the generics being used should have to have been quality checked and be the same as Norco as we have survived 28 plus years without going to stronger or more meds and would like it to be put back like it was. If a company cannot produce the medication right they should have to resign from manufacturing it."

8 / 10
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34 Report
  • MeToo
  • Taken for 10 years or more
  • August 7, 2023

"I'm with other people who have complained about the Mallinckrodt brand. It's garbage. I had an allergic reaction to it (I'm on 10/325s). To be fair, I do have a hard time with medications of any kind, and hydrocodone is the only pain medication I can tolerate. I'm on pain management and have to call every pharmacy in town every month to find a different brand, and it's getting worse. The only one I found last month is $236 for my prescription. I have no choice but to pay it again this month."

8 / 10
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15 Report
  • Shana
  • Taken for less than 1 month
  • March 29, 2022

Norco (acetaminophen / hydrocodone) "Note to Dentists/Oral Surgeons: Please do NOT RX no 5 mg. Generic Norco for extractions and/or abscessed teeth!!! Jesus, this weak stuff did NOT even give me one iota of pain relief!! WTH, WHY are people having to suffer? Years ago, I'd say 20 years ago was the last time I had an abscessed tooth & was rx'd 5 mg vicodin and it worked great! It gave me so much relief after 2 long days and nights in severe pain. So recently I had another bad abscessed tooth and was rx'd the same, 5 mg hydrocodone. I couldn't believe it, absolutely NOTHING, NO relief at all! I've read others reviews on here so I know it's not just me. You better believe we are being done over when it comes to these medications. Someone told me it's these generic one and the FDA in the U.S. cowers to them, gives them 3 weeks advance notice before showing up to audit their facilities, records/tests on these CRAPPY meds. There is also someone on Ted Talk spilling the beans about these meds! Write the FDA!"

1 / 10
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32 Report
  • Greg
  • Taken for 2 to 5 years
  • January 3, 2020

"I've been taken norco for 3 yrs. My last two prescriptions have been the imprint wes 303 the manufacturer Wes Pharma Inc. and labelled under the Eywa Pharma Inc. brand. Never had any issues until I started taken these. I can't function, get out of bed and insomnia threw the roof. I never had this issue. I feel as if I am withdrawing all the time. I will be asking my dr to prescribe a different brand. It has been making me sick. Not sure if I am allergic to fillers or not. Please report if have same issue. I will return a message when get back on a different brand to report difference. Btw, never had issues with m367 pills."

1 / 10
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55 Report
  • Robert...
  • Taken for 10 years or more
  • April 7, 2016

Vicodin (acetaminophen / hydrocodone) "I had knee surgery in 2001. The surgeon screwed up a nerve and I have been in chronic pain (24/7) since. Vicodin works better than anything else I've tried, including morphine. Without it, I am in pain and can't sleep at night. I can now understand why people commit suicide because they can't take the pain anymore."

10 / 10
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88 Report
  • Diana
  • Taken for 1 to 6 months
  • May 29, 2023

"I agree totally with these other people. I have 2 compression fractures and bulges all down my back. I also have neck and shoulder issues. I have taken Norco for many years but recently had to change pharmacies because mine decided to sell out to Walgreens. Since then I have been getting the ER pills and I have called an ambulance 4 times with 2 taking me to the ER. The last one was today. My blood pressure was 175/84 and my heart rate was 140. I was very dizzy and lightheaded, my throat swelled, my lips felt swollen, was nauseous, and had a headache every time. These pills cause more problems than they are worth to me. I pray the powers that be have the presence of mind to give us our medicine back before I end up having a stroke."

2 / 10
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17 Report
  • Rose
  • Taken for less than 1 month
  • September 27, 2022

"This medicine does not work for pain at all!! It also gave me a horrific nightmares, after taking only 1 tablet of my 1 month refill, I can’t take it at all. What a waste of money! Plus my pain and suffering!!! I am in chronic pain, and have been on Hydrocodone for many years. I am furious I get to deal with my pain without any pain meds. What are you putting in this?? THERE IS NO PAIN RELIEF AT ALL WITH THIS MANUFACTURER! We are at the mercy of the big pharma, and the Insurance companies!!!! Doctors don’t believe the generics do not work. The pharmacy’s say there isn’t anything they can do because it’s what they ordered in bulk!!! So who is responsible for this? Who CAN WE HOLD ACCOUNTABLE FOR THIS??? I am sick and tired of these manufacturers of generic drugs getting away with this! While we get charged a lot and the pharmacy makes money, along with the pharmaceutical companies, THIS DOESN'T WORK AT ALL!! MY NITROSTAT DIDN’T work either (different company)"

1 / 10
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25 Report
  • kamde...
  • April 26, 2017

Norco (acetaminophen / hydrocodone) "I'm a 54 yo woman with chronic back leg and arm pain due to degenerative disc disease. My whole lumbar is fused. 3 herniated discs in the thoracic and 5 now in the cervical that need repair. I rely on Norco just to be able to get out of bed sometimes and to do chores like cut the grass. One of the best I've taken, Only thing I've noticed is I don't sleep when I take it. I just rest. I'm now lost as the laws are changing and my surgeon cannot give me scripts due to being post surgical a year. Family Dr doesn't issue narcotics at all, so I ended up at a high priced pain clinic that will only prescribe 5/325 2x a day! what a joke....... those of us that need it can't get it ."

9 / 10
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76 Report
  • miss...
  • Taken for 10 years or more
  • October 11, 2021

Norco (acetaminophen / hydrocodone) "I watch my father suffer in pain & lethargy, he’s taken this medicine for many years yet it’s changed in side effects & effectiveness. How do I get my father better pain medicine, how do I get my old dad back while he’s still here with me. Is this intentional? Are they making pain medicine horrible on purpose? How do we fix it?"

4 / 10
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35 Report
  • Manda...
  • Taken for 10 years or more
  • April 10, 2023

"I've been in pain management since 2012 and was Rx'd hydrocodone/APAP 5-325. The Watson brand worked great. Fast forward to 2022 and the pharmacy switched to Mallinckrodt. It didn't control my pain and made me very nauseous which I hadn't experienced before, and it also made me itchy. I had to take Benadryl before taking it to control the nausea and itching. I hadn't made the connection to how I was reacting to it until last Friday when my pharmacy switched to a different manufacturer, Lupin. I took my pill before bed and noticed that it looked different. I forgot to take Benadryl beforehand so I thought I was in for a rough night. Lo and behold, no nausea and no itching! Wondering if Mallinckrodt puts extra things in theirs that shouldn't be. Either that or it's possibly the bitartrate, which I don't think Lupin uses in theirs. After seeing the reviews here, I now know I'm NOT crazy and it's not all in my head! Lupin: 10 stars. Mallinckrodt: 0 (sad trombone)."

10 / 10
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18 Report
  • Doesnt...
  • Taken for 5 to 10 years
  • May 4, 2022

"The mallinkcroft 10/325 ARE AN ABSOLUTE JOKE!! Unfortunately out crooked government won't look into the negative claims from users of the drug cause they consider us junkies and pill heads. These pills are TRASH and need to be pulled from the market. Too many kick backs for politicians for them to step up. Do yourself a favor and demand your pharmacy to not sell this worthless, filler full junk !!!!"

1 / 10
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28 Report
  • Anonymous
  • March 14, 2020

"10 years of taking these with little problems and just refilled and I have been bleeding out of nose and mouth and urine since getting a new batch of medication. Dr is too worried about the bleeding and I am in pain, what is in these pills."

1 / 10
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48 Report
  • Chron...
  • Taken for 5 to 10 years
  • July 13, 2021

"Report ALL issues to the FDA. They have a form you can submit to have the issue investigated. I just got switched to Mallinckrodt acetaminophen with hydrocodone and immediately noticed they didn’t work. The only brand of acetaminophen and hydrocodone that worked the best was Watson since they started using all the other manufacturers I haven’t found one that works as well When I was switched to Mallinckrodt I looked online to find the manufacturer and found a ton of others making the same claims as I was experiencing I hope everyone is making the reports to get this stuff off the market There is absolutely something different about these meds the active ingredient or percent of opioid must be off or something Google fda consumer reporting"

1 / 10
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35 Report
  • Sannda
  • Taken for 10 years or more
  • September 28, 2022

"I have tried every generic pill of this medication. Can't take any of them. I use to always use Watson which was excellent. But, Watson went out of business. The generics now available make me extremely sick. The sickness lasts into the next day after taking just 1 generic pill. Found no relief from the pain. But...I just come across one Hydrocodone/Acetaminophen that I CAN handle. It is made by Rhodes. Well worth your time to look into this heaven-sent medication/"

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23 Report
  • Take...
  • Taken for 1 to 6 months
  • September 23, 2021

Norco (acetaminophen / hydrocodone) "These Generic pain medications are horrible. Many times they have NO MANUFACTURE name on them. I am being given one now that gives me vertigo every single day, all day long. I loose my balance, have severe headaches, nauseated and blurry vision. These side effects have me bed ridden now. I am drowsy and sleep ALOT. There was a note on my account with the pharmacy to not give this brand to me, but NOW I am being told, " YOU GET WHAT WE HAVE" I was willing to pay out of pocket for name brand, I was told " NO ONE STOCKS NAME BRAND ANY MORE. I went to every pharmacy in our area and called ones that were not so close. I now don't have the energy to move and take care of many things. If I don't take them, I am in too much pain. Just as bad is the attitudes of the pharmacist now thinking it's open season on people who need these medications. They talk over me , they talk down to me and everyone ignores me and act like I am not a person"

3 / 10
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33 Report
  • Painful...
  • August 12, 2019

"So as everyone above! It is sooo sad that we have to suffer because our voice doesn't count!! I am in extreme pain and it just seems like nobody cares? Watson was a great relief for me But now, Nothing just gives me headaches upset stomach and sleepiness? When I wake up pain still there. Not sure what to do as I am truly sick doctors know it! But they have no say in what pharmacies carry! I am upset with Walgreens as I have been with them for 12 years ."

1 / 10
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51 Report
  • Amy
  • Taken for 10 years or more
  • July 27, 2019

"I have been taking various opioids for over 10 different painful health issues which I will not go into here, because I would be here all day. A few however are Ankylosing Spondolitis, and Scoliosis. I have been taking pain meds for over 10 years now. I was prescribed 2 different pain meds, but have been reduced to only one now. I chose the lower back pain all the time. Feeling like I have the flu all the time tried not only my physical pain, but also my emotional when feeling this way. They carried the 10 mg pills from a certain manufacturer that were rectangular shaped. COMPLAIN TO THE FDA..they KNOW WE ARE ON TO THEM!! FILE COMPLAINTS, START PETITIONS!!! NONE of the people who control opioid pain meds actually have ANY TYPE OF SEVERE pain! They are INSULTING OUR INTELLIGENCE!!! "

1 / 10
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51 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.