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Acetaminophen / hydrocodone User Reviews & Ratings (Page 2)

Brand names: Xodol Zyfrel

Acetaminophen / hydrocodone has an average rating of 6.1 out of 10 from a total of 1,305 reviews on Drugs.com. 51% of reviewers reported a positive experience, while 34% reported a negative experience.

Reviews for Acetaminophen / hydrocodone

  • Inthe...
  • Taken for 1 to 6 months
  • August 23, 2020

Norco (acetaminophen / hydrocodone) for Pain "The generic hydrocodone/ acetaminophen combo has turned into absolute garbage in the US. In my experience pharmacies are just purchasing the cheapest product they can find, which increases all the bad effects of an opioid while providing very little pain relief. Opioids are the only drug class you can't even pay extra for the name brand for, all thanks to pharmacy/insurance company policy. It is absurd. Honestly, it should be illegal. Luckily my doctor is willing to switch me to percocet or oxy (which is almost impossible in todays age) so I'm glad. On the other hand I seem to have a weirdly high tolerance to oxy. Either way report this to the drug manufacturers (mallinckrodt, Tris, etc) is the only way. The FDA is filled people who don't answer the phone, so reporting to the manufacturers as well is best."

2 / 10
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  • Anonymous
  • Taken for 10 years or more
  • April 21, 2023

Norco (acetaminophen / hydrocodone) for Back Pain "I have several medical issues and have been living with pain for 30 years. I take my medication as prescribed, and I try to take less when possible. However, the medication that is currently available is not working for me. I am 68 years old and trying to stay active, but this medication is causing me to be bedridden. The yellow generic for Norco used to work for me, but it is no longer available, and the current white pills are not providing any relief. I am tired of hearing people say that "it's the same medicine" because it is not. I just want to be able to be up and active again. If anyone knows of a lawsuit, I would be interested in joining."

1 / 10
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79 Report
  • Bring...
  • Taken for 10 years or more
  • November 20, 2019

Norco (acetaminophen / hydrocodone) for Pain "When the Watson brand of acetaminophen / hydrocodone was available this medication was wonderful. The last 2 months I noticed a difference in my prescription not working effectively. I honestly could feel little to no relief and excessive drowsiness through out the day. I called the pharmacy and found out the manufacturer was Mallinckrodt. After reading reviews about others taking this brand I have decided to talk to my Pain specialist and switch medications rather than try to search for a pharmacy with a different brand. Good luck to you all and I pray that we all get some relief from ongoing pain. #Peaceandlove"

3 / 10
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239 Report
  • Sue
  • Taken for 10 years or more
  • July 24, 2020

For Rheumatoid Arthritis "I can tell you right now the Mallinckrodt hydrocodone has been changed ! I don’t think there is anything in them for pain , I believe they are taking it off market. I, for one, don’t know what I’m going to do. I’m 60 I’ve had 5 back surgeries, 1 neck surgeries I have been in pain for 13 years and have been taking the same dose for just as long ! I’m sick to my stomach , puke , I’ve had a cluster headache for over two months, dizzy, gain weight , tired all the time ! Why would the government do this to people that truly need this medication. I’m not a kid sneaking pills out of the medicine cabinet ! I wish I knew who to call about Mallinckrodt ! This stuff is nasty I’m worried there is something going into it that could really hurt us ! My god what can we do ?"

2 / 10
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  • MissN...
  • February 17, 2020

Norco (acetaminophen / hydrocodone) for Back Pain "I was given Norco because of stenosis and herniated disc which happened on the job and because I'm in a program of recovery I did not want to take it however the pain became too great and I was getting a great generic version of Norco acetaminophen/hydrocodone now the only thing that is available is Mallinckrodt and before that I had a manufacturer Eywa.. ( THOSE ARE AWFUL) however Mallinckrodt is the best I can come up with because Watson no longer makes this medication and the looks from the pharmacy just because it doesn't look like I have anything wrong doesn't mean that there isn't. My doctor has shared with me that he won't increase my dosage even though my condition is chronic nor will he change it to Percocet because I would have to go to a hearing I don't know if anyone has ever heard of any of these things but if you have please share I'm in Ohio the Cleveland area. I'm just tired and NO ONE should have to deal with substandard medicines but what about those of us who have chronic pain?"

4 / 10
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Are you taking this medicine?

  • JBano
  • March 17, 2020

Lortab (acetaminophen / hydrocodone) for Pain "This pill didn't do much of anything before but now days they do even less. Are they doing something to the pain meds so that they are not consistent ever.!!! Some months you get a script that's amazing an other times they make you feel so bad your head hurts an etc. But the feds and gov have there hands in every thing so I'm sure there knocking everything off so can't trust any of them anymore. It is nothing like it use to be..."

1 / 10
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  • Anony...
  • Taken for 10 years or more
  • May 26, 2020

For Back Pain "I have chronic back pain from an injury to 5th lumbar region. I had back surgery in 1997. The surgery gave me pain relief for two years, and that was it. Now my entire back hurts from top to bottom with pain going down left leg. I have been taking hydrocodone since 2003, and it has always worked for me. Giving me enough pain relief to live an active life. Within the last two years I have noticed that the hydrocodone wasn't taking away my pain like it use to. Now it doesn't work at all. My last prescription was Tris PHARMA brand. This medication is comparable to Mallinckrodt brand. I have nausea, ringing in ears, headaches, and severe dizziness. I feel like I am going to fall over when I get up. Is there anyone out there who can help us? Who represents the people who have to take pain medications to live? My quality of life is now gone. We need help here!"

1 / 10
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  • Pharm...
  • Taken for 10 years or more
  • March 6, 2022

Norco (acetaminophen / hydrocodone) for Pain "Please send a MEDWATCH 3500 form to the FDA about Norco generic. FDA dot GOV The FDA will not read your post here. Medwatch 3500 form is a simple one page document that will help the FDA open an investigation on the generic manufacturers. NORCO generic is NOT AB Rated! Available USA generics are AA rated, meaning they only passed a dissolution test in acetone with a report that has been submitted to the FDA. This does NOT mean it is therapeutically equivalent to the reference brand. That is why you are experiencing more pain, that is because these manufacturers are NOT making therapeutically equivalent drugs that you are taking. Again, they are NOT AB Rated. Currently there is no open investigation on generic Norco! You have to submit the Medwatch 3500 Form! This exists because we need people on this site to submit a FDA Medwatch 3500 Form via mail, FAX or Email, then if enough complaints are logged, then only then will there will be action. Please act now, send the Form"

1 / 10
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110 Report
  • Natalie
  • Taken for 2 to 5 years
  • August 19, 2019

Norco (acetaminophen / hydrocodone) for Back Pain "I use to get name brand things were fine. My back pain started getting worse then I got the generics. First it was good. Some were good some not. In the Aurobindo brand of acetaminophen/hydrocodone after about 2 weeks I started to vomit and was sick for a week. Of course pharmacy didn't listen. Then one more time and same thing happened. No more of that. Then Mallinckrodt. It's just rubbish. Now Im having spasms in buttocks. I don't think there is any opiate in them and I am withdrawing. You can't trust big pharma. That's the way they do things. I am angry because they are stealing from us. How dare they decide for us that we should not have opiates."

2 / 10
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  • Anonymous
  • February 19, 2020

Norco (acetaminophen / hydrocodone) for Back Pain "Back and neck looks like a train wreck without going into a long drawn out post. Waiting for a surgery because dr is out of town. Pain dr says be patient. I’m not out of pain. Been on Norco for 15 years. Looking at a 3rd neck fusion and 4 herniations, disc protruding and other MRI findings. Dr is scared to prescribe medication. I’ve actually thought about street drugs to relieve my pain. It’s not addiction it’s desperation for chronic pain relief!!!"

5 / 10
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  • Suki
  • April 24, 2021

Norco (acetaminophen / hydrocodone) for Pain "Absolute garbage. Ibuprofen works better for my tooth pain. I ended up doubling my dose and still no relief. I don’t know what the manufacturers are doing to pain pills these days but it’s wrong on so many levels."

1 / 10
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  • Pain...
  • Taken for 10 years or more
  • November 18, 2018

Norco (acetaminophen / hydrocodone) for Pain "I have been on Norco for 13 years for pain relief and have no side effects. The main problem is finding a doctor to prescribe them. Many doctors mistakenly think by cutting down or stopping writing scripts for Norco, there are less overdoses. Actually the people that legitimately take it for pain are suffering and the people abusing it have switched to heroin, which there are many more ODs from. Heroin is not controlled so it can contain deadly ingredients; also an addict could be used to a certain strength and unknowingly buy something stronger that could kill them. This law has caused more deaths, but most doctors haven't done the research I have and don't know this. I think the doctors should get personally involved with the patients; I would gladly answer any questions and give permission for them to check my legal history. Then hopefully the people in pain would get help and the people abusing drugs could go to rehab to get off it. That's when we'll see a drop in ODs and deaths."

10 / 10
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  • Jazz
  • Taken for less than 1 month
  • January 31, 2019

Norco (acetaminophen / hydrocodone) for Back Pain "I was taking actavis norco 10/325 for years and as you all stated no one carries them anymore. The Mallinckrodt makes me so sick that I did research Par pharmaceuticals the yellow ones is wholesaled by AmerisourceBergen and AmerisourceBergens largest contract is with Walgreens and Riteaid. I called around and Par told me you are with AmerisourceBergen and that you can order par. The 24 hour locations can try but they are mostly stocked fully with Mallinckrodt and can’t order past a certain threshold. Call the locations that are open to 9pm. BOTH of the non 24 hour Walgreens were able to go in their system pull up Par yellow norco and order them. They also notated my file that I have a bad reaction on Mallinkcrodt and can only be filled actavis (which is still made I called them as well) or Par. Hope this helps."

8 / 10
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  • Arkan...
  • Taken for 10 years or more
  • January 16, 2021

For Pain "The old yellow hydros with the checkmark were the best for helping my chronic pain. Now all pharmacies have the mallinckrodt M367 white ones which may as well be sugar pills. Very little effect if any, the government just can't stop hurting all of us who actually need pain medicine due to all the other people overdosing. No idea how the FDA hasn't done anything about this!!! Terrible!!"

2 / 10
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  • Lady...
  • February 22, 2020

For Back Pain "I was prescribed "Hydrocodone/Acedeminiphen 7.5- 3.25" for Sciatic Pain & Fibromyalgia Pain. I have been taking this medication for quite some time and it works/worked, until Walgreens, switched manufacturers, going from "Watson" to "Mallinckrodt". This pain med has so much filler and hardly any actual pain reliever in it. I've had to take/use more to get any relief; And that makes me look like I'm abusing/misusing my prescriptions. This company is really doing us a disservice, not to mention being dishonest & fraudulent. I asked a couple of Pharmacist if anyone else has complained about this medication ( from this manufacturer) not working for them? He said there had indeed been other complaints. Mallinckrodt Pharmaceutical products are on the same level as Placebos. This is so unfair, when we are suffering with legitimate pain. I am pleading with Walgreens, Walmart & other Pharmacies to Stop buying from this company. We Need Real Meds. This Patient/Consumer is calling them out!"

1 / 10
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143 Report
  • Fritz
  • June 8, 2020

For Rheumatoid Arthritis "I suffer from rheumatoid arthritis and have been on Hydrocodone 10/325 for about 2 years, and when the generics stopped working, or made me sick, this website helped me find a brand that works. First, my bad experience was with Lupin (severe nausea and headache with little pain relief) and Mallinckrodt (which used to work but a few months ago stopped being effective). The yellow pills with the V on them are the only ones that work, they are made by Qualitest, which is now Par pharmaceuticals. None of the big retail pharmacy chains will order them. I called several local pharmacies until I found one who will order them and keep them in stock for me. They’re only open 5 days a week and I have to drive about 35-40 minutes round trip to get them, but it’s worth it. I hope this can help others, and thank you to those of you who recommended this brand to me. I finally have my quality of life back."

9 / 10
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135 Report
  • Pain...
  • Taken for 5 to 10 years
  • June 15, 2020

Lortab (acetaminophen / hydrocodone) for Back Pain "This is by far the worst brand of hydrocodone I have ever taken. Makes me sick to my stomach and does not on my back pain at all. And it's a waste of a prescription. Watson brand is by far the best with no side effects and does its job. I do not know what fillers you're putting in this junk but you need to take it off the market. I had to change my pharmacy to get a brand that works because of your side effects of this junk. I couldn't be more serious. I'm after pain relief not a high and certainly not to be sick at my stomach from taking it."

1 / 10
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131 Report
  • J B
  • February 7, 2020

For Back Pain "ATTENTION PEOPLE! Complain to the FDA in writing, and complain to the CDC as well. These government agencies are requiring all manufacturers of generic opioids to reformulate the medications so they will be less addictive. In the process the medication itself has become ineffective, and simply does not work. The last time my medication worked was February 23, 2019. Since then it has been downhill. We need to let our voices be heard! I hope a lawyer reads all of these posts, and files a class action lawsuit against the FDA, CDC, and the drug manufacturers. I complain to the FDA, and CDC every time I get my pain medication filled. Every generic I have tried has been ineffective. It’s time for something to be done! Thanks to this post I now know I am not alone!"

1 / 10
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  • Jasmine
  • Taken for 10 years or more
  • July 16, 2019

For Pain "I'm a pharmacist with migraines and have been taking Watson brand Norco 10/325mg for 10 years. Usually, a 1/2 tab is plenty or 1 tab, if needed. 60 tabs lasts me a year. Just got 30 tabs made by Lupin. An hour after taking 1, I felt like I hadn't taken anything, so I took another. I have never had to take 2! Still no relief. No difference between the different brands? As a pharmacist, who is definitely not addicted or dependent since I rarely take it, I'm telling you this isn't true. I'd like to test the 2 brands' ingredients and the quantities of each. If they have the same amount of active ingredients, the issue could then be the inactive ones. The Lupin brand works for some, but is it because that was the 1st brand they had taken or is it because some people's bodies process inactive ingredients differently? The Lupin brand doesn't work for me and others and it isn't fair that we must suffer because this is the only brand the pharmacy will dispense."

1 / 10
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  • bobbi
  • Taken for 5 to 10 years
  • November 1, 2019

Norco (acetaminophen / hydrocodone) for Back Pain "I have had back pain for years but didn’t see a Dr. until the last few years. Recently had back surgery. I’ve taken Norco off and on and it does help with the pain but it just doesn’t last long and I need a high dose that makes me sleepy. My big complaint is the restrictions on opioids. If I have MRI reports that indicate I have a real need for them why do I have to go every month to get a prescription? I understand patients make up illnesses to get them, but if there’s no indication at all they need to not receive them. It shouldn’t affect someone who does."

4 / 10
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  • Still...
  • Taken for 10 years or more
  • July 6, 2021

For Back Pain "I live in the area of one of US's largest urban areas, & want to know WHY do Norcos (hydrocodone with acetaminophen) no longer work for pain??? I have been taking them for 16+ years for spinal root damage. Never built up a tolerance & continued to take as prescribed, with no issues. Now, they just don't work at all! Is this yet another way the Feds are "punishing" us for the alleged opiate crisis?? You're doing it wrong!! 83% of last year's record ODs were a result of illicit fentanyl with most of the rest being heroin & meth. Only 1.4% had a legit script for them! DO SOMETHING GOOD for a change, Washington!! This is a national disgrace!!"

1 / 10
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  • FakeD...
  • Taken for 10 years or more
  • March 9, 2022

For Pain "Aurobindo hydrocodone 10mg/325 is NOT AB Rated for USA consumption. My opinion, it is a placebo, sugar pill with bad ingredients. Do not use Mallinckrodt. The solution is to order through your pharmacy Vicodin HP 10/300 bottles of 100. Your MD has to write specifically for this product made by Abbott in Chicago. The difference in a AB rated product is huge and meets all bioavailability requirements by the FDA."

1 / 10
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  • Kraci
  • Taken for less than 1 month
  • January 12, 2019

Norco (acetaminophen / hydrocodone) for Pain "I have had times when I've had to take Norco for pain. Most of which was Watson. I had knee surgery Dec 28 and was given Norco 5/325 from Aurobindo pharmaceuticals. I took 2-3 at a time to feel ANY RELIEF. This brand is no better than OTC meds. I never knew until now that different companies use different ingredients. I'm so disappointed in my pharmacy for changing companies at the cost of their suffering clientele."

1 / 10
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  • Malef...
  • Taken for 10 years or more
  • December 11, 2018

Norco (acetaminophen / hydrocodone) for Back Pain "I had been taking the Watson 10/325 Norco with no problems, until Walgreens went to Mallinckrodt; total waste of time. I was told by Walgreens, that Watson no longer existed and found that unacceptable. They are worlds apart and I don’t know how they’re getting away with this. Wait, yes I do! Those that need these meds to work, so we function in life; are also victims of the opioid epidemic. So I did some research... Watson was bought out by one of two companies. Next, I began calling pharmacies, asking the brand carried. All the chain stores had the Mallinckrodt, CVS flat refused to answer & said they’d reject my prescription if I came in and asked. FINALLY, I found two local pharmacies that had different brands. I have gone to both pharmacies to try them and discovered that any brand OTHER than the Mallinckrodt works just fine. So my advice to anyone in this predicament is to try local pharmacies and step away from the Mallinckrodt garbage."

9 / 10
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  • Jkano
  • Taken for 1 to 6 months
  • February 21, 2019

Norco (acetaminophen / hydrocodone) for Back Pain "I had cancer and an auto immune disorder which ended with several surgeries and resulted in a lot of generalized pain. My doc prescribed Norco 5/325 three times a day then had to double the dose. Mallinkrot was pharm manufacturer. This medicine absolutely did nothing for pain and actually caused other issues such as GI problems including abdominal cramps and nausea. After switching to another brand my pain was relieved significantly and no abdominal issues. As a medical professional I do not recommend this manufacturer EVER."

1 / 10
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140 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.