Generic name: Risperidone Injection (subcutaneous) [ ris-PER-i-done ]
Brand name: Perseris
Drug class: Atypical antipsychotics
Medically reviewed by Drugs.com. Last updated on Mar 24, 2023.
- There is a higher chance of death in older adults who take risperidone injection (subcutaneous) for mental problems caused by dementia. Most of the deaths were linked to heart disease or infection. This medicine is not approved to treat mental problems caused by dementia.
Uses of Risperidone Injection:
- It is used to treat schizophrenia.
- It may be given to you for other reasons. Talk with the doctor.
What do I need to tell my doctor BEFORE I take Risperidone Injection?
- If you are allergic to risperidone injection (subcutaneous); any part of risperidone injection (subcutaneous); or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
This medicine may interact with other drugs or health problems.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take risperidone injection (subcutaneous) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Risperidone Injection?
- Tell all of your health care providers that you take risperidone injection (subcutaneous). This includes your doctors, nurses, pharmacists, and dentists.
- Avoid driving and doing other tasks or actions that call for you to be alert until you see how risperidone injection (subcutaneous) affects you.
- To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. Be careful going up and down stairs.
- High blood sugar or diabetes, high cholesterol, and weight gain have happened with drugs like this one. These may raise the chance of heart and brain blood vessel disease.
- Check your blood sugar as you have been told by your doctor.
- Avoid drinking alcohol while taking risperidone injection (subcutaneous).
- Dizziness, sleepiness, and feeling less stable may happen with risperidone injection (subcutaneous). These may lead to falling, which can cause broken bones or other health problems.
- Low white blood cell counts have happened with drugs like this one. This may lead to a higher chance of infection. Rarely, infections have been deadly. Tell your doctor if you have ever had a low white blood cell count. Call your doctor right away if you have signs of infection like fever, chills, or sore throat.
- Some people may get a severe muscle problem called tardive dyskinesia. This problem may lessen or go away after stopping risperidone injection (subcutaneous), but it may not go away. The risk is greater with diabetes and in older adults, especially older women. The risk is greater with longer use or higher doses, but it may also occur after short-term use with low doses. Call your doctor right away if you have trouble controlling body movements or problems with your tongue, face, mouth, or jaw like tongue sticking out, puffing cheeks, mouth puckering, or chewing.
- Older adults with dementia taking drugs like this one have had a higher number of strokes. Sometimes these have been deadly. This medicine is not approved to treat mental problems caused by dementia.
- A lump may happen where the shot was given. The lump may last for several weeks and get smaller over time. Do not rub or massage the area. Be careful of placing belts or clothing waistbands over the area where the shot was given.
- If you are 65 or older, use risperidone injection (subcutaneous) with care. You could have more side effects.
- This medicine may affect being able to get pregnant. This effect goes back to normal when the drug is stopped. If you have questions, talk with the doctor.
- Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. You will need to talk about the benefits and risks to you and the baby.
- Taking risperidone injection (subcutaneous) in the third trimester of pregnancy may lead to uncontrolled muscle movements and withdrawal in the newborn.
How is this medicine (Risperidone Injection) best taken?
Use risperidone injection (subcutaneous) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- Be careful in hot weather or while being active. Drink lots of fluids to stop fluid loss.
- It may take several weeks to see the full effects.
- Talk with your doctor before you use other drugs and natural products that slow your actions.
- Some products need to be given into the fatty part of the skin. Some products need to be given into a muscle. Talk with the doctor or pharmacist if you are not sure how to use risperidone injection (subcutaneous).
What do I do if I miss a dose?
- Call your doctor to find out what to do.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of high blood sugar like confusion, feeling sleepy, more thirst, more hungry, passing urine more often, flushing, fast breathing, or breath that smells like fruit.
- Very bad dizziness or passing out.
- Change in how you act.
- Mood changes.
- Shakiness, trouble moving around, or stiffness.
- Not able to pass urine or change in how much urine is passed.
- Trouble swallowing or speaking.
- Not able to focus.
- Change in eyesight.
- Shortness of breath.
- Enlarged breasts, nipple discharge, not able to get or keep an erection (in males), or period (menstrual) changes (in females).
- Sex problems like lowered interest in sex or ejaculation problems.
- Call your doctor right away if you have a painful erection (hard penis) or an erection that lasts for longer than 4 hours. This may happen even when you are not having sex. If this is not treated right away, it may lead to lasting sex problems and you may not be able to have sex.
- A very bad and sometimes deadly health problem called neuroleptic malignant syndrome (NMS) may happen. Call your doctor right away if you have any fever, muscle cramps or stiffness, dizziness, very bad headache, confusion, change in thinking, fast heartbeat, heartbeat that does not feel normal, or are sweating a lot.
What are some other side effects of Risperidone Injection?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Weight gain.
- Feeling dizzy, sleepy, tired, or weak.
- Constipation, diarrhea, stomach pain, upset stomach, or throwing up.
- Dry mouth.
- More hungry.
- Runny or stuffy nose.
- Nose or throat irritation.
- Trouble sleeping.
- Back pain.
- Muscle pain.
- Irritation where the shot is given.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Risperidone Injection?
- If you need to store risperidone injection (subcutaneous) at home, talk with your doctor, nurse, or pharmacist about how to store it.
Consumer Information Use and Disclaimer
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about risperidone injection (subcutaneous), please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
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