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Morphine soluble tablets


Generic Name: morphine (MOR-feen)
Brand Name: Generic only. No brands available.

Morphine soluble tablets are used for:

Treating moderate to severe pain. It may also be used before surgery to aid sedation and anesthesia.

Morphine soluble tablets are a narcotic pain reliever. It works by dulling the pain perception center in the brain. It may also affect other body systems (eg, respiratory and circulatory systems) at higher doses.

Do NOT use morphine soluble tablets if:

  • you are allergic to any ingredient in morphine soluble tablets
  • you have severe diarrhea caused by antibiotic use
  • you are taking sodium oxybate (GHB)
  • you have slowed breathing or are having an asthma attack
  • you are having a seizure

Contact your doctor or health care provider right away if any of these apply to you.

Before using morphine soluble tablets:

Some medical conditions may interact with morphine soluble tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have had a severe allergic reaction (eg, severe rash, hives, difficulty breathing, dizziness) to any morphine-related medicine (eg, codeine)
  • if you have a history of alcohol or drug abuse or dependence or suicidal thoughts or actions
  • if you have a history of lung or breathing problems (eg, asthma, chronic obstructive pulmonary disease [COPD], sleep apnea) or low blood oxygen levels
  • if you have severe drowsiness, increased pressure in the head, recent head injury, growths in the brain, or a history of seizures
  • if you have trouble urinating, urinary blockage, or a history of kidney or liver problems; heart problems (eg, fast or irregular heartbeat); underactive thyroid; enlarged prostate; endocrine problems (eg, Addison disease); curvature of the spine (scoliosis); or seizures
  • if you have low blood pressure, low blood volume, stomach or intestinal problems (eg, blockage, inflammatory bowel disease, severe or chronic constipation), or have had stomach or intestinal surgery

Some MEDICINES MAY INTERACT with morphine soluble tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Phenothiazines (eg, chlorpromazine) because the risk of low blood pressure may be increased
  • Fluoxetine, naltrexone, narcotic agonists/antagonists (eg, pentazocine), rifampin, or risperidone because they may decrease morphine soluble tablets's effectiveness
  • Barbiturate anesthetics (eg, thiopental), cimetidine, ketorolac, sodium oxybate (GHB), or tricyclic antidepressants (eg, amitriptyline) because side effects (eg, disorientation, respiratory depression, seizures) may occur
  • Mexiletine or trovafloxacin because their effectiveness may be decreased by morphine soluble tablets

This may not be a complete list of all interactions that may occur. Ask your health care provider if morphine soluble tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use morphine soluble tablets:

Use morphine soluble tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Do NOT take morphine soluble tablets by mouth. Morphine soluble tablets are intended to be dissolved for injection.
  • Morphine soluble tablets are usually given as an injection at your doctor's office, hospital, or clinic. If you will be using morphine soluble tablets at home, a health care provider will teach you how to use it. Be sure you understand how to use morphine soluble tablets. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
  • Do not use morphine soluble tablets if it is cloudy or discolored, or contains particles after mixing. Do not use morphine soluble tablets if the solution is darker than pale yellow.
  • Take morphine soluble tablets on a regular schedule to get the most benefit from it. It is more effective in preventing pain than in treating pain after it occurs.
  • Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
  • If you miss a dose of morphine soluble tablets and you are using it regularly, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once. Contact your doctor if you are unsure what to do if you miss a dose of morphine soluble tablets.

Ask your health care provider any questions you may have about how to use morphine soluble tablets.

Important safety information:

  • Morphine soluble tablets may cause dizziness or drowsiness. These effects may be worse if you take it with alcohol or certain medicines. Use morphine soluble tablets with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Do not drink alcohol while you are using morphine soluble tablets.
  • Check with your doctor before you use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using morphine soluble tablets; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
  • Morphine soluble tablets may cause constipation. Using a stool softener or fiber laxative may help decrease this effect.
  • The risk of morphine soluble tablets becoming habit-forming may be greater if you take it in high doses or for a long time. Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.
  • Tell your doctor or dentist that you take morphine soluble tablets before you receive any medical or dental care, emergency care, or surgery.
  • Do not take morphine soluble tablets if you have had a severe allergic reaction to morphine or hydromorphone (eg, MS Contin, Roxanol, Dilaudid). If you have a question about whether you are allergic to morphine soluble tablets or if a certain medicine contains morphine or hydromorphone, contact your doctor or pharmacist.
  • Lab tests, including liver function, kidney function, lung function, and complete blood cell counts, may be performed while you use morphine soluble tablets. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Use morphine soluble tablets with caution in the ELDERLY; they may be more sensitive to its effects.
  • Morphine soluble tablets should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using morphine soluble tablets while you are pregnant. Morphine soluble tablets are found in breast milk. If you are or will be breast-feeding while you use morphine soluble tablets, check with your doctor. Discuss any possible risks to your baby.

When used for long periods of time or at high doses, morphine soluble tablets may not work as well and may require higher doses to obtain the same effect as when originally taken. This is known as TOLERANCE. Talk with your doctor if morphine soluble tablets stops working well. Do not take more than prescribed.

Some people who use morphine soluble tablets for a long time may develop a need to continue taking it. People who take high doses are also at risk. This is known as DEPENDENCE or addiction. If you stop taking morphine soluble tablets suddenly, you may have WITHDRAWAL symptoms. These may include anxiety; diarrhea; fever, runny nose, or sneezing; goose bumps and abnormal skin sensations; nausea; vomiting; pain; rigid muscles; rapid heartbeat; seeing, hearing or feeling things that are not there; shivering or tremors; sweating; and trouble sleeping.

Possible side effects of morphine soluble tablets:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; dizziness; drowsiness; exaggerated sense of well-being; headache; lightheadedness; nausea; restless mood; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, throat, or tongue); excessive drowsiness; hallucinations; pounding in the chest; seizures; shock; shortness of breath; sudden chest pain; unusual or excessive sweating.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center ( ), or emergency room immediately. Symptoms may include cold, clammy, or blue skin; convulsions; deep sleep; limp muscles; loss of consciousness; low body temperature; severe dizziness, drowsiness, or lightheadedness; slowed breathing; slowed heartbeat.

Proper storage of morphine soluble tablets:

Store morphine soluble tablets between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep morphine soluble tablets out of the reach of children and away from pets.

General information:

  • If you have any questions about morphine soluble tablets, please talk with your doctor, pharmacist, or other health care provider.
  • Morphine soluble tablets are to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about morphine soluble tablets. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Review Date: July 5, 2017

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.