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Active substance(s): HYDROCORTISONE

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Hydrocortisone 10 mg
This medicine is called Hydrocortisone 10 mg tablets but will be
referred to as Hydrocortisone tablets throughout this leaflet.
This leaflet contains important information about
Hydrocortisone Tablets.
Read this leaflet carefully before you start taking this
• Keep this leaflet. You may need to read it again.
• If you have further questions, please ask your doctor or your
• This medicine has been prescribed for you personally and you
should not pass it on to others. It may harm them, even if their
symptoms are the same as yours.
• If any of the side effects get serious, or if you notice any side
effects not listed in this leaflet, please tell your doctor or
• Hydrocortisone tablets are a steroid medicine, prescribed
for many different conditions, including serious illnesses
• You need to take it regularly to get the maximum benefit
• Don’t stop taking this medicine without talking to your doctor
- you may need to reduce the dose gradually
• Hydrocortisone Tablets can cause side effects in some
people (read ‘Possible side effects’ section below). Some
problems such as mood changes (feeling depressed, or ‘high’),
or stomach problems can happen straight away. If you feel
unwell in any way, keep taking your tablets, but see your
doctor straight away
• Some side effects only happen after weeks or months.
These include weakness of arms and legs, or developing a
rounder face (read ‘Possible side effects’ section for more
• If you take it for more than 3 weeks, you will get a blue
‘steroid card’: always keep it with you and show it to any
doctor or nurse treating you
• Keep away from people who have chicken-pox or shingles,
if you have never had them. They could affect you severely. If
you do come into contact with chicken pox or shingles, see
your doctor straight away.
Now read the rest of this leaflet. It includes other important
information on the safe and effective use of this medicine that
might be especially important for you.
In this leaflet
1)What Hydrocortisone tablets are and what are they used
2)Before taking Hydrocortisone tablets
3)How to take Hydrocortisone tablets
4)Possible side effects
5)How to store Hydrocortisone tablets
6)Further information

• you have a herpes infection in the eye called ocular herpes
• you had muscle weakness after taking steroids in the past
• you have recently visited a tropical country
• you have bowel problems such as ulcerative colitis
• you have epilepsy
• you have thrombophlebitis (swelling and redness along a vein
which is extremely tender when touched)
• you have exanthematous disease (disease affecting the skin,
• you have metastatic carcinoma (cancer that has spread from
one part of the body to another)
• you are taking Hydrocortisone Tablets for a long time increases
your chance of getting infections
• you have amoebic dysentery and an infestation of a gut worm
(strongyloidiasis), it may be activated or become worse.
Also, check with your doctor if any of the following problems run
in your family, or if you have any of them:
• diabetes
• heart problems
• high blood pressure
• an eye condition called ‘glaucoma’
• kidney or liver problems
• a type of muscle weakening problem called ‘myasthenia gravis’
• thinning of the bones (osteoporosis)
• low thyroid levels (hypothyroidism).
If you are not sure if any of the above run in your family, or you
have them, talk to your doctor or pharmacist before taking a

Mental Problems while taking Hydrocortisone Tablets
Mental problems can happen while taking steroids like
Hydrocortisone Tablets (see also section 4 Possible Side
• These illnesses can be serious.
• Usually they start within a few days or weeks of starting the
• They are more likely to happen at high doses.
• Most of these problems go away if the dose is lowered or the
medicine is stopped.
• However, if problems do happen they might need treatment.
Talk to a doctor if you (or someone taking this medicine), shows
any signs of mental problems.
This is particularly important if you are depressed, or might be
thinking about suicide. In a few cases, mental problems have
happened when doses are being lowered or stopped.

Taking other medicines
Tell your doctor or pharmacist if you are taking or have recently
taken any other medicines including those obtained without a
prescription. This includes herbal medicines. This is because
Hydrocortisone Tablets can affect the way some medicines work.
Also, some other medicines can affect the way Hydrocortisone
Tablets work.

• are allergic (hypersensitive) to hydrocortisone or any of the
other ingredients of Hydrocortisone Tablets
• have thrush, candida or any other fungal infection.

In particular do not take this medicine and tell your doctor or
pharmacist if you are taking any of the following:
• aspirin
• medicines for fits (epilepsy) such as phenytoin, phenobarbital,
carbamazepine and primidone
• cough and cold medicines that contain a decongestant called
• medicines used for TB (tuberculosis) called rifabutin or
• medicines used to thin the blood such as warfarin
• water tablets (diuretics)
• some medicines for fungal infections such as amphotericin and
• a medicine for cancer called aminoglutethimide
• some medicines for heart failure such as digoxin, furosemide
or bumetanide
• a medicine used for some infections called erythromycin
• oral contraceptive pills and hormone replacement therapy
• a type of growth hormone called somatropin
• some medicines for high blood pressure
• some medicines for heart disease such as guanethidine,
isosorbide mononitrate, isosorbide dinitrate and theophylline
• medicines sometimes used for asthma, low blood pressure or
in cough and cold remedies called sympathomimetics
• calcium supplements
• medicines for pain and inflammation called NSAIDs such as
ibuprofen, diclofenac or naproxen
• a medicine for urea cycle disorder called sodium
phenylbutyrate (usually started by a specialist doctor or
• medicines for diabetes.
• ritonavir (a medicine used in the treatment of HIV infections)
• methotrexate (a medicine used to treat rheumatoid arthritis)
• Ciclosporin (a medicine used for psoriasis or in patients who
have organ transplants)
• minoxidil & hydralazine (used for antihypertensive)

If you are not sure talk to your doctor or pharmacist before taking
Hydrocortisone Tablets.

If you are not sure if any of the above apply to you, talk to your
doctor or pharmacist before taking Hydrocortisone Tablets.

Take special care with Hydrocortisone Tablets

Hydrocortisone Tablets and infections

Hydrocortisone Tablets contain a medicine called hydrocortisone.
This belongs to a group of medicines called ‘steroids’. Their full
name is corticosteroids. These corticosteroids occur naturally in
the body, and help to maintain health and well-being. Boosting
your body with extra corticosteroid (such as Hydrocortisone
Tablets) is an effective way to treat various illnesses involving
inflammation in the body.
Hydrocortisone Tablets reduce this inflammation, which could
otherwise go on making your condition worse. You must take this
medicine regularly to get maximum benefit from it.
Hydrocortisone Tablets are used for:
• adding hydrocortisone usually made naturally in the body
because part of the adrenal gland is not working properly
• adding hydrocortisone after injuries, surgery or other stressful
• some other types of illness.
Ask your doctor to explain why you have been given
Hydrocortisone Tablets if you are unsure.

Before you take Hydrocortisone Tablets
Check with your doctor first if
• You have ever had severe depression or manic depression
(bipolar disorder). This includes having had depression before
or while taking steroid medicines like Hydrocortisone Tablets.
• any of your close family has had these illnesses.
If either of these applies to you, talk to a doctor before taking
Hydrocortisone Tablets.

Do not take Hydrocortisone Tablets if you:

Check with your doctor before taking your medicine if:
• you have recently had a heart attack
• you have a heart condition called congestive heart disease
• you have septicaemia, tuberculosis (TB) or have had it in the
• you have a stomach ulcer or other digestive problem
• you have chicken pox or shingles
• you come in contact with people who have chicken pox or
shingles, especially if you have not already had these illnesses
or are not sure if you have had them

Infections are easier to get and harder to spot while you are
taking Hydrocortisone Tablets.
Stay away from anyone you know with:
• chickenpox
• shingles
• measles.
See your doctor if you think you may have picked up an infection.

Pregnancy and breast-feeding
Talk to your doctor before taking this medicine if you are
pregnant, might become pregnant or are breastfeeding.

Driving and using machines
Steroids may cause a feeling of movement, even while you are
still and this can cause you to feel dizzy (vertigo). Changes in
your eyesight or muscle weakness may also happen. If you are
affected you should not drive or operate machinery.

Taking Hydrocortisone Tablets with food and drink
Hydrocortisone Tablets can be taken with or without food.

Having vaccines or tests while you are taking
Hydrocortisone Tablets
Tell your doctor that you are taking Hydrocortisone Tablets if you
are to receive any vaccinations or have any diagnostic or
laboratory tests. This is because steroids can affect the results of
some tests.

Having surgery while you are taking Hydrocortisone
If you are having surgery requiring an anaesthetic tell your doctor
you are taking Hydrocortisone Tablets.

Information you should carry while you are taking
Hydrocortisone Tablets
If you are taking Hydrocortisone Tablets, get a steroid card from
your pharmacist, and carry it with you. It shows what you are
taking and who your doctor is in case of an emergency.
If you have an accident, fall ill or see a different doctor while
taking Hydrocortisone Tablets, show them your steroid card or,
tell whoever treats you that you are taking Hydrocortisone
Tablets, because your dose may need to be changed.

Important information about some of the ingredients of
Hydrocortisone Tablets
Hydrocortisone Tablets contain lactose, which is a type of sugar.
If you have been told by your doctor that you cannot tolerate or
digest some sugars (have an intolerance to some sugars), talk to
your doctor before taking this medicine.

Always take Hydrocortisone Tablets exactly as your doctor has
told you. You should check with your doctor or pharmacist if you
are not sure.

Taking this medicine
You should take this medicine by mouth. The amount you take
each day will depend on your illness. The number of tablets to be
taken will be on the label of your medicine. If you are unsure
about the dose you should take, you must talk to your doctor or
pharmacist. The usual doses of Hydrocortisone Tablets are:
• 20 to 30 mg a day.
• Sometimes it is taken with 4 to 6 g of salt (sodium chloride) or
50 to 300 micrograms of fludrocortisone.
• 0.4 to 0.8 mg a day, for every kilogram of your child’s weight in
two or three separate doses.
• Children will be prescribed the lowest possible dose.
• The doctor will keep an eye on their growth and development.

If you take more Hydrocortisone Tablets than you should
If you take too many tablets by mistake, contact your doctor as
soon as possible.

If you forget to take Hydrocortisone Tablets
• If you forget to take your dose, skip the missed dose.
• Take the next dose as normal.
• Do not take a double dose to make up for a forgotten dose.

If you are thinking about stopping or have recently been
told to stop Hydrocortisone Tablets
It is dangerous to reduce your dose of Hydrocortisone Tablets
too quickly. Stopping Hydrocortisone Tablets may leave you
without enough steroid hormones in your body. This may cause
withdrawal symptoms such as:
• pains in muscles or joints
• fever
• general discomfort.
Your doctor or pharmacist will give you advice on how to reduce
the number of tablets you take if you need to do this.
If you have any further questions on the use of this product, ask
your doctor or pharmacist.

Like all medicines, Hydrocortisone Tablets can cause side
effects, although not everybody gets them. People taking
steroids to replace similar naturally occurring hormones, should
be less likely to get side effects than, people taking steroids for
other illnesses. Your doctor will want to see you now and then to
look out for these effects.
Tell your doctor straight away if you notice any of these
problems, or if you think you are at increased risk of infection
(e.g. you have been in contact with someone who has an
• An allergic reaction such as skin rash, swelling of the face or
• Irregular or very fast or slow pulse, faintness.
• Muscle cramps or spasms.
• Pseudotumourcerebri in children (raised pressure within the
skull, indicated by headaches with vomiting, listlessness and
drowsiness); this usually occurs after treatment is stopped.
• Nausea, vomiting.
• Burst or bleeding ulcers (indicated by stomach pain especially
if it seems to spread to your back, bleeding from the back
passage, black stools or vomiting with blood in the vomit).
• Acute pancreatitis (abdominal pain, possibly accompanied by
shock, i.e. low blood pressure with decreased output of urine
and often loss of consciousness).
• A worsening of sight.

• Thrombosis (a blood clot in a vein in your leg, symptoms of
which are a swollen, red, hot, tender muscle).
• Thromboembolism (a blood clot which may go to the lung,
symptoms of which are sudden chest pain and coughing up
• Heart failure - problems with the pumping of your heart
indicated by swollen ankles, chest pain, difficulty in breathing
and palpitations or irregular beating of the heart, irregular or
very fast or slow pulse; hypertension (high blood pressure,
indicated by headaches, or generally feeling unwell).
Steroids including Hydrocortisone Tablets can cause serious
mental health problems. These are common in both adults and
children. They can affect about 5 in every 100 people taking
medicines like Hydrocortisone Tablets.
• Feeling depressed, including thinking about suicide.
• Feeling high (mania) or moods that go up and down.
• Feeling anxious, having problems sleeping, difficulty in thinking
or being confused and losing your memory.
• Feeling, seeing or hearing things which do not exist. Having
strange and frightening thoughts, changing how you act or
having feelings of being alone.
Tell your doctor if you experience any of the following:
Effects on your digestive system
• Swollen abdomen.
• Ulcers or thrush in the gullet (discomfort on swallowing).
• Indigestion.
• Bloating
• Hiccups
Effects on your muscles and bones
• Muscle weakness or wasting.
• Osteoporosis (brittle bones – bones that break easily).
• Broken bones or fractures
• Breakdown of bone due to poor circulation of blood (pain in the
• Aseptic necrosis (joint inflammation in the knee and groin).
• Torn muscle tendons (pain and/or swelling).
Effects on your body water and salts
• Cramps and spasms due to the loss of the potassium salts
from your body. In rare cases, loss of potassium can lead to
palpitations (an uneven beating of your heart that you become
aware of).
Effects on your hormones and metabolic system
• Suppression of normal growth in children
• Irregular or no periods in women.
• increased hair on the body and face in women
• round or moon-shaped face
• increased appetite and weight gain
• Increase in blood sugar levels, breakdown of body protein
stores (loss of weight and muscle loss in arms or legs), loss of
calcium and nitrogen.
Effects on your skin
• thin or delicate skin, bruising, red or purple spots
• slow healing of cuts or wounds
• acne, sweating, redness
• stretch marks
Effects on your eyes
• changes in vision as a result of cataracts or glaucoma
(increased pressure inside the eye)
• thinning of the surface of the eye
• eye infections may get worse
• bulging eyes.
Reporting of side effects: If you get any side effects, talk to
your doctor, pharmacist or nurse. This includes any possible side
effects not listed in this leaflet. You can also report side effects
directly via the Yellow Card Scheme at: By reporting side effects you can
help provide more information on the safety of this medicine.


Keep out of the reach and sight of children
Do not store above 25°C.
Store them in the original package to protect from light.
Do not use Hydrocortisone Tablets after the expiry date, which
is marked on the outside of the pack. The expiry date refers to
the last day of that month.
• Medicines should not be disposed of via wastewater or
household waste. Ask your pharmacist how to dispose of
medicines no longer required. These measures will help to
protect the environment.
• If the tablets show any signs of deterioration seek the advice of
your pharmacist.

• Each tablet contains 10 mg Hydrocortisone. The other
ingredients are lactose, magnesium stearate and maize starch.
Hydrocortisone 10 mg tablets are white, oval and marked HYD
10 on one side and scored in quarters on the reverse. This can
allow you to take lower dose of half of a tablet (5mg) or quarter of
a tablet (2.5mg).
Hydrocortisone Tablets come in packs of 30 tablets.

Manufacturer and Product Licence Holder
Manufactured by: TioFarma, Benjamin Franklinstraat 10, 3261
LW Oud-Beijerland, Netherlands.
It is procured within the EU and repackaged by Mediwin Limited,
Product Licence Holder: Mediport Limited,
13 Martello Enterprise Centre, Courtwick Lane, Littlehampton,
West Sussex, BN17 7PA, United Kingdom.


PL: 18980/0864 Hydrocortisone 10 mg tablets

Date of leaflet preparation: 10/02/2015



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Source: Medicines and Healthcare Products Regulatory Agency

Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.