Mobic Side Effects

Generic name: meloxicam

Medically reviewed by Drugs.com. Last updated on Oct 21, 2024.

Note: This document provides detailed information about Mobic Side Effects associated with meloxicam. Some dosage forms listed on this page may not apply specifically to the brand name Mobic.

Applies to meloxicam: intravenous solution.

Other dosage forms:

• oral capsule, oral suspension, oral tablet, oral tablet disintegrating

Important warnings This medicine can cause some serious health issues

Intravenous route (solution)

NSAIDs cause an increased risk of serious cardiovascular thrombotic events, including myocardial infarction and stroke, which can be fatal.

This risk may occur early in treatment and may increase with duration of use.

Meloxicam is contraindicated in the setting of coronary artery bypass graft surgery.

NSAIDs cause an increased risk of serious gastrointestinal (GI) adverse events including bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal.

These events can occur at any time during use and without warning symptoms.

Elderly patients and patients with a prior history of peptic ulcer disease and/or GI bleeding are at greater risk for serious GI events.

Serious side effects of Mobic

Along with its needed effects, meloxicam (the active ingredient contained in Mobic) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking meloxicam:

Less common side effects

• abdominal or stomach pain, cramping, burning, or tenderness
• bloody or black, tarry stools
• constipation
• dark urine
• decreased appetite
• diarrhea
• fever
• headache
• heartburn
• indigestion
• itching or skin rash
• loss of appetite
• nausea and vomiting
• swelling of the feet or lower legs
• trouble breathing
• unusual tiredness or weakness
• vomiting of material that looks like coffee grounds, severe and continuing
• yellow eyes or skin

Incidence not known

• blistering, peeling, or loosening of the skin
• bloody or cloudy urine
• cough or hoarseness
• decrease in the frequency of urination
• decrease in urine volume
• diarrhea
• difficulty in passing urine (dribbling)
• difficulty swallowing
• dizziness
• fast heartbeat
• fever with or without chills
• general feeling of tiredness or weakness
• greatly decreased frequency of urination or amount of urine
• hives
• lower back or side pain
• pains in the chest, groin, or legs, especially calves of the legs
• painful or difficult urination
• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• red, irritated eyes
• severe headaches of sudden onset
• sore throat
• sores, ulcers, or white spots on the lips or in the mouth
• sudden loss of coordination
• sudden onset of shortness of breath for no apparent reason
• sudden onset of slurred speech
• sudden vision changes
• swelling of the feet or lower legs
• tightness in the chest
• unusual bleeding or bruising

Other side effects of Mobic

Some side effects of meloxicam may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

• bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site

For healthcare professionals

Applies to meloxicam: intravenous dispersion, oral capsule, oral suspension, oral tablet, oral tablet disintegrating.

General adverse events

The most frequently reported side effects were diarrhea, upper respiratory tract infections, dyspepsia, nausea, abdominal discomfort, and influenza-like symptoms.^[Ref]

Gastrointestinal

• Very common (10% or more): Dyspepsia, nausea, vomiting, abdominal pain, constipation, flatulence, diarrhea
• Common (1% to 10%): Abdominal discomfort, gastrointestinal (GI) irritation, aggravated dyspepsia, eructation, gastroesophageal reflux disease, upper abdominal pain
• Uncommon (0.1% to 1%): Occult or macroscopic GI hemorrhage, gastritis, stomatitis
• Rare (0.01% to 0.1%): Colitis, gastroduodenal ulcer, esophagitis
• Very rare (less than 0.01%): GI perforation
• Frequency not reported: Dry mouth, duodenal ulcer, gastric ulcer, gastritis, hematemesis, hemorrhagic duodenal ulcer, hemorrhagic gastric ulcer, intestinal perforation, melena, pancreatitis, perforated duodenal ulcer, perforated gastric ulcer, stomatitis ulcerative^[Ref]

Cardiovascular

• Common (1% to 10%): Hypertension
• Uncommon (0.1% to 1%): Flushing
• Rare (less than 0.1%): Palpitations
• Frequency not reported: Hot flushes, angina pectoris, cardiac failure, hypotension, myocardial infarction, vasculitis, arrhythmia, palpitation, tachycardia, shock, cardiac failure^[Ref]

Nervous system

• Common (1% to 10%): Dizziness, headache, carpel tunnel syndrome
• Uncommon (0.1% to 1%): Somnolence
• Frequency not reported: Syncope, convulsions, paresthesia, tremor, taste perversion^[Ref]

Respiratory

• Common (1% to 10%): Pharyngitis, upper respiratory tract infection, coughing, nasopharyngitis, bronchitis, sinusitis, laryngitis, pleuritic pain, dyspnea, rhinitis
• Rare (less than 0.1%): Asthma
• Frequency not reported: Bronchospasm^[Ref]

Other

• Common (1% to 10%): Accident household, edema, fall, influenza-like symptoms, pain, peripheral edema, gravitational edema, fatigue, ear disorder, vertigo, fall
• Frequency not reported: Face edema, fever, malaise, weight decreased, weight increased, tinnitus
• Postmarketing reports: Meningitis^[Ref]

Hematologic

• Common (1% to 10%): Anemia
• Rare (0.01% to 0.1%): Blood count abnormal, leukopenia, thrombocytopenia
• Very rare (less than 0.01%): Agranulocytosis^[Ref]

Dermatologic

• Common (1% to 10%): Rash, pruritus, erythematous rash, maculopapular rash, hyperhidrosis, purpura
• Uncommon (0.1% to 1%): Angioedema
• Rare (0.01% to 0.1%): Stevens-Johnson syndrome, toxic epidermal necrolysis, urticaria
• Very rare (less than 0.01%): Dermatitis bullous, erythema multiforme
• Frequency not reported: Alopecia, bullous eruption, exfoliative dermatitis, photosensitivity reaction, sweating increased
• Postmarketing reports: Erythema multiforme^[Ref]

Hypersensitivity

• Common (1% to 10%): Hypersensitivity
• Uncommon (0.1% to 1%): Allergic reactions
• Frequency not reported: Anaphylactoid reaction
• Postmarketing reports: Anaphylactoid reactions including shock^[Ref]

Endocrine

• Postmarketing reports: Female infertility^[Ref]

Musculoskeletal

• Common (1% to 10%): Arthralgia, aggravated arthralgia, joint crepitation, joint effusion, joint swelling, back pain, osteoarthritis, pain in extremity, arthritis, bursitis, muscle spasms, myalgia, rheumatoid arthritis^[Ref]

Genitourinary

• Common (1% to 10%): Micturition frequency, urinary tract infection, hematuria
• Frequency not reported: Acute urinary retention^[Ref]

Hepatic

• Uncommon (0.1% to 1%): Liver function disorder, ALT increased, AST increased, bilirubinemia
• Very rare (less than 0.01%): Hepatitis
• Frequency not reported: GGT increased, jaundice, liver failure^[Ref]

Psychiatric

• Common (1% to 10%): Insomnia
• Rare (less than 0.1%): Nightmares, mood alterations
• Frequency not reported: Abnormal dreaming, anxiety, confusion, depression, nervousness, disorientation
• Postmarketing reports: Alterations in mood such as mood elevation^[Ref]

Renal

• Very rare (less than 0.01%): Acute renal failure, papillary necrosis, acute tubular necrosis
• Frequency not reported: Albuminuria, BUN increased, creatinine increased, interstitial nephritis, renal failure^[Ref]

Metabolic

• Common (1% to 10%): Dehydration, appetite increased
• Uncommon (0.1% to 1%): Sodium retention, hyperkalemia, water retention^[Ref]

Ocular

• Common (1% to 10%): Cataract
• Rare (less than 0.1%): Visual disturbances, conjunctivitis, blurred vision
• Frequency not reported: Abnormal vision^[Ref]

Frequently asked questions

• Is meloxicam very similar to Celebrex?
• Meloxicam vs Ibuprofen: What's the difference?
• Should I take meloxicam at night or in the morning?
• Can I take Meloxicam and Aleve or Tylenol together?
• How much meloxicam can I give my dog?
• Which painkiller should you use?
• How long do I wait after taking ibuprofen to take meloxicam?
• Can meloxicam cause drowsiness and headache?

Further information

Mobic side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer