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Mobic Side Effects

Generic name: meloxicam

Medically reviewed by Drugs.com. Last updated on Feb 23, 2023.

Note: This document contains side effect information about meloxicam. Some dosage forms listed on this page may not apply to the brand name Mobic.

Summary

More frequent side effects include: abdominal pain, anemia, and edema. Continue reading for a comprehensive list of adverse effects.

Applies to meloxicam: intravenous solution.

Warning

Intravenous route (Solution)

NSAIDs cause an increased risk of serious cardiovascular thrombotic events, including myocardial infarction and stroke, which can be fatal. This risk may occur early in treatment and may increase with duration of use. Meloxicam is contraindicated in the setting of coronary artery bypass graft surgery. NSAIDs cause an increased risk of serious gastrointestinal (GI) adverse events including bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal. These events can occur at any time during use and without warning symptoms. Elderly patients and patients with a prior history of peptic ulcer disease and/or GI bleeding are at greater risk for serious GI events.

Serious side effects of Mobic

Along with its needed effects, meloxicam (the active ingredient contained in Mobic) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking meloxicam:

Less common

Incidence not known

  • Blistering, peeling, or loosening of the skin
  • bloody or cloudy urine
  • cough or hoarseness
  • decrease in the frequency of urination
  • decrease in urine volume
  • diarrhea
  • difficulty in passing urine (dribbling)
  • difficulty swallowing
  • dizziness
  • fast heartbeat
  • fever with or without chills
  • general feeling of tiredness or weakness
  • greatly decreased frequency of urination or amount of urine
  • hives
  • lower back or side pain
  • pains in the chest, groin, or legs, especially calves of the legs
  • painful or difficult urination
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • red, irritated eyes
  • severe headaches of sudden onset
  • sore throat
  • sores, ulcers, or white spots on the lips or in the mouth
  • sudden loss of coordination
  • sudden onset of shortness of breath for no apparent reason
  • sudden onset of slurred speech
  • sudden vision changes
  • swelling of the feet or lower legs
  • tightness in the chest
  • unusual bleeding or bruising

Other side effects of Mobic

Some side effects of meloxicam may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

  • Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site

For Healthcare Professionals

Applies to meloxicam: intravenous dispersion, oral capsule, oral suspension, oral tablet, oral tablet disintegrating.

General

The most frequently reported side effects were diarrhea, upper respiratory tract infections, dyspepsia, nausea, abdominal discomfort, and influenza-like symptoms.[Ref]

Gastrointestinal

Very common (10% or more): Dyspepsia, nausea, vomiting, abdominal pain, constipation, flatulence, diarrhea

Common (1% to 10%): Abdominal discomfort, gastrointestinal (GI) irritation, aggravated dyspepsia, eructation, gastroesophageal reflux disease, upper abdominal pain

Uncommon (0.1% to 1%): Occult or macroscopic GI hemorrhage, gastritis, stomatitis

Rare (0.01% to 0.1%): Colitis, gastroduodenal ulcer, esophagitis

Very rare (less than 0.01%): GI perforation

Frequency not reported: Dry mouth, duodenal ulcer, gastric ulcer, gastritis, hematemesis, hemorrhagic duodenal ulcer, hemorrhagic gastric ulcer, intestinal perforation, melena, pancreatitis, perforated duodenal ulcer, perforated gastric ulcer, stomatitis ulcerative[Ref]

Cardiovascular

Common (1% to 10%): Hypertension

Uncommon (0.1% to 1%): Flushing

Rare (less than 0.1%): Palpitations

Frequency not reported: Hot flushes, angina pectoris, cardiac failure, hypotension, myocardial infarction, vasculitis, arrhythmia, palpitation, tachycardia, shock, cardiac failure[Ref]

Nervous system

Common (1% to 10%): Dizziness, headache, carpel tunnel syndrome

Uncommon (0.1% to 1%): Somnolence

Frequency not reported: Syncope, convulsions, paresthesia, tremor, taste perversion[Ref]

Respiratory

Common (1% to 10%): Pharyngitis, upper respiratory tract infection, coughing, nasopharyngitis, bronchitis, sinusitis, laryngitis, pleuritic pain, dyspnea, rhinitis

Rare (less than 0.1%): Asthma

Frequency not reported: Bronchospasm[Ref]

Other

Common (1% to 10%): Accident household, edema, fall, influenza-like symptoms, pain, peripheral edema, gravitational edema, fatigue, ear disorder, vertigo, fall

Frequency not reported: Face edema, fever, malaise, weight decreased, weight increased, tinnitus

Postmarketing reports: Meningitis[Ref]

Hematologic

Common (1% to 10%): Anemia

Rare (0.01% to 0.1%): Blood count abnormal, leukopenia, thrombocytopenia

Very rare (less than 0.01%): Agranulocytosis[Ref]

Dermatologic

Common (1% to 10%): Rash, pruritus, erythematous rash, maculopapular rash, hyperhidrosis, purpura

Uncommon (0.1% to 1%): Angioedema

Rare (0.01% to 0.1%): Stevens-Johnson syndrome, toxic epidermal necrolysis, urticaria

Very rare (less than 0.01%): Dermatitis bullous, erythema multiforme

Frequency not reported: Alopecia, bullous eruption, exfoliative dermatitis, photosensitivity reaction, sweating increased

Postmarketing reports: Erythema multiforme[Ref]

Hypersensitivity

Common (1% to 10%): Hypersensitivity

Uncommon (0.1% to 1%): Allergic reactions

Frequency not reported: Anaphylactoid reaction

Postmarketing reports: Anaphylactoid reactions including shock[Ref]

Endocrine

Postmarketing reports: Female infertility[Ref]

Musculoskeletal

Common (1% to 10%): Arthralgia, aggravated arthralgia, joint crepitation, joint effusion, joint swelling, back pain, osteoarthritis, pain in extremity, arthritis, bursitis, muscle spasms, myalgia, rheumatoid arthritis[Ref]

Genitourinary

Common (1% to 10%): Micturition frequency, urinary tract infection, hematuria

Frequency not reported: Acute urinary retention[Ref]

Hepatic

Uncommon (0.1% to 1%): Liver function disorder, ALT increased, AST increased, bilirubinemia

Very rare (less than 0.01%): Hepatitis

Frequency not reported: GGT increased, jaundice, liver failure[Ref]

Psychiatric

Common (1% to 10%): Insomnia

Rare (less than 0.1%): Nightmares, mood alterations

Frequency not reported: Abnormal dreaming, anxiety, confusion, depression, nervousness, disorientation

Postmarketing reports: Alterations in mood such as mood elevation[Ref]

Renal

Very rare (less than 0.01%): Acute renal failure, papillary necrosis, acute tubular necrosis

Frequency not reported: Albuminuria, BUN increased, creatinine increased, interstitial nephritis, renal failure[Ref]

Metabolic

Common (1% to 10%): Dehydration, appetite increased

Uncommon (0.1% to 1%): Sodium retention, hyperkalemia, water retention[Ref]

Ocular

Common (1% to 10%): Cataract

Rare (less than 0.1%): Visual disturbances, conjunctivitis, blurred vision

Frequency not reported: Abnormal vision[Ref]

Frequently asked questions

References

1. "Product Information. Mobic (meloxicam)." Boehringer-Ingelheim (2001):

2. Cerner Multum, Inc. "Australian Product Information." O 0

3. MHRA. Medicines and Health Regulatory Agency "MHRA Drug Safety Update. http://www.mhra.gov.uk/Safetyinformation/DrugSafetyUpdate" (2013):

4. "Product Information. Anjeso (meloxicam)." Baudax Bio, Inc. (2020):

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Medical Disclaimer