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Medications for Zollinger-Ellison Syndrome

Zollinger-Ellison syndrome is caused by gastrin-secreting tumors of the pancreas that causes severe ulceration (areas of irritation) of the upper gastrointestinal tract (stomach and small bowel).

Drugs used to treat Zollinger-Ellison Syndrome

The medications listed below are related to or used in the treatment of this condition.

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Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
pantoprazole Rate Add review
Rx B N
Generic name:
pantoprazole systemic
Brand names:
Protonix, Protonix IV
Drug class:
proton pump inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
omeprazole 10 1 review for omeprazole to treat Zollinger-Ellison Syndrome
Rx/OTC C N
Generic name:
omeprazole systemic
Brand name:
Prilosec
Drug class:
proton pump inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Protonix Rate Add review
Rx B N
Generic name:
pantoprazole systemic
Drug class:
proton pump inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
famotidine Rate Add review
Rx/OTC B N
Generic name:
famotidine systemic
Brand names:
Pepcid AC, Pepcid, Heartburn Relief, Acid Controller Maximum Strength, Acid Controller Original Strength, Pepcid AC Chewable Tablets, Pepcid Oral Suspension
Drug class:
H2 antagonists
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Nexium Rate Add review
Rx C N
Generic name:
esomeprazole systemic
Drug class:
proton pump inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
lansoprazole Rate Add review
Rx/OTC B N
Generic name:
lansoprazole systemic
Brand names:
Prevacid, Prevacid OTC, Prevacid SoluTab
Drug class:
proton pump inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Prevacid Rate Add review
Rx B N
Generic name:
lansoprazole systemic
Drug class:
proton pump inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Prilosec 10 1 review for Prilosec to treat Zollinger-Ellison Syndrome
Rx C N
Generic name:
omeprazole systemic
Drug class:
proton pump inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
cimetidine Rate Add review
Rx/OTC B N X
Generic name:
cimetidine systemic
Brand name:
Tagamet HB
Drug class:
H2 antagonists
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Pepcid AC Rate Add review
OTC B N
Generic name:
famotidine systemic
Drug class:
H2 antagonists
For consumers:
dosage, interactions, side effects
rabeprazole Rate Add review
Rx B N
Generic name:
rabeprazole systemic
Brand name:
Aciphex
Drug class:
proton pump inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Pepcid Rate Add review
Rx B N
Generic name:
famotidine systemic
Drug class:
H2 antagonists
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
esomeprazole Rate Add review
Rx/OTC C N
Generic name:
esomeprazole systemic
Brand names:
Nexium, Nexium IV
Drug class:
proton pump inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Aciphex Rate Add review
Rx B N
Generic name:
rabeprazole systemic
Drug class:
proton pump inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Heartburn Relief Rate Add review
OTC B N
Generic name:
famotidine systemic
Drug class:
H2 antagonists
For consumers:
dosage, interactions, side effects
Protonix IV Rate Add review
Rx B N
Generic name:
pantoprazole systemic
Drug class:
proton pump inhibitors
For consumers:
dosage, interactions, side effects
Tagamet HB Rate Add review
Rx/OTC B N X
Generic name:
cimetidine systemic
Drug class:
H2 antagonists
For consumers:
dosage, interactions, side effects
Prevacid OTC Rate Add review
OTC B N
Generic name:
lansoprazole systemic
Drug class:
proton pump inhibitors
For consumers:
dosage, interactions, side effects
Acid Controller Maximum Strength Rate Add review
OTC B N
Generic name:
famotidine systemic
Drug class:
H2 antagonists
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Acid Controller Original Strength Rate Add review
OTC B N
Generic name:
famotidine systemic
Drug class:
H2 antagonists
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Pepcid AC Chewable Tablets Rate Add review
OTC B N
Generic name:
famotidine systemic
Drug class:
H2 antagonists
For consumers:
dosage, interactions, side effects
Nexium IV Rate Add review
Rx C N
Generic name:
esomeprazole systemic
Drug class:
proton pump inhibitors
For consumers:
dosage, interactions, side effects
Pepcid Oral Suspension Rate Add review
Rx B N
Generic name:
famotidine systemic
Drug class:
H2 antagonists
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Amphojel Rate Add review
Rx/OTC N N
Generic name:
aluminum hydroxide systemic
Drug class:
antacids, phosphate binders
For consumers:
dosage, interactions, side effects
aluminum hydroxide Rate Add review
Rx/OTC N N
Generic name:
aluminum hydroxide systemic
Brand name:
Amphojel
Drug class:
antacids, phosphate binders
For consumers:
dosage, interactions, side effects

Frequently asked questions

Learn more about Zollinger-Ellison Syndrome

Care guides

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Expanded Access Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.