Zoledronic acid Alternatives Compared
| Zoledronic acid | Evenity (romosozumab) | Alendronate |
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| Zoledronic acid | Evenity (romosozumab) | Alendronate |
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Prescription only
Zoledronic acid strengthens bones and is used to manage several different bone-related conditions. Zoledronic acid injection (Reclast, 5 mg/100 mL) is used to treat and prevent postmenopausal or... View more |
Prescription only
Prescribed for Osteoporosis. Evenity may also be used for purposes not listed in this medication guide. |
Prescription only
Alendronate helps to reduce the risk of fracture in people with osteoporosis and some other bone conditions. Dosage instructions, including remaining upright for at least 30 minutes and taking with a... View more |
Related suggestions Osteoporosis
Popular comparisons
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| More about Zoledronic acid | More about Evenity (romosozumab) | More about Alendronate | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Zoledronic acid has an average rating of 5.0 out of 10 from a total of 411 ratings on Drugs.com. 35% of reviewers reported a positive effect, while 46% reported a negative effect. |
Evenity has an average rating of 6.6 out of 10 from a total of 76 ratings on Drugs.com. 49% of reviewers reported a positive effect, while 18% reported a negative effect. |
Alendronate has an average rating of 2.8 out of 10 from a total of 185 ratings on Drugs.com. 17% of reviewers reported a positive effect, while 78% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||||||||||
View all Zoledronic acid side effects |
View all Evenity side effects |
View all Alendronate side effects |
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| Drug Class | ||||||||||||||||||||||||||
| Generic Availability | ||||||||||||||||||||||||||
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Lower cost generic |
N/A |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Zoledronic acid prices |
View all Evenity prices |
View all Alendronate prices |
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| Dosage Forms | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Aclasta, Reclast, Zometa |
N/A |
Binosto, Fosamax | ||||||||||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||||||||||
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N/A |
307.2 hours |
N/A |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 123 drugs are known to interact with Zoledronic acid:
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A total of 47 drugs are known to interact with Evenity:
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A total of 118 drugs are known to interact with Alendronate:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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December 28, 2015 |
April 09, 2019 |
September 29, 1995 |
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| WADA Class View classifications | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
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| Related Treatment Guide | ||||||||||||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.