Comparing Topiramate vs Valproate Sodium
| Topiramate | Valproate Sodium (valproic acid) |
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| Topiramate | Valproate Sodium (valproic acid) |
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Prescription only
Topiramate may be prescribed either alone or in combination with other medications for the treatment of certain types of epilepsy, or it may be given for the prevention of migraines. Drowsiness is a... View more |
Prescription only
Prescribed for Epilepsy, Seizure Prevention, Seizures. Valproate Sodium may also be used for purposes not listed in this medication guide. |
Related suggestions Seizures
Seizure Prevention (Seizure Prophylaxis)
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| More about Topiramate | More about Valproate Sodium (valproic acid) | ||||||||
| Ratings & Reviews | |||||||||
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Topiramate has an average rating of 6.3 out of 10 from a total of 1332 ratings on Drugs.com. 51% of reviewers reported a positive effect, while 28% reported a negative effect. |
Valproate Sodium has an average rating of 3.7 out of 10 from a total of 3 ratings on Drugs.com. 33% of reviewers reported a positive effect, while 67% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||
View all Topiramate side effects |
View all Valproate Sodium side effects |
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| Drug Class | |||||||||
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None |
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| Generic Availability | |||||||||
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Lower cost generic |
Lower cost generic approved | ||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||
View all Topiramate prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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| Dosage Forms | |||||||||
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| Brand Names | |||||||||
| Eprontia, Qudexy XR, Topamax, Trokendi XR |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||
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56 hours |
16 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||
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Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Category D
Positive evidence of risk
When Treating Epilepsy
Category X
Not for use in pregnancy
When Treating Migraine See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||
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A total of 291 drugs are known to interact with Topiramate:
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A total of 426 drugs are known to interact with Valproate Sodium:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
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| Disease Interactions | |||||||||
| First Approval Date | |||||||||
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December 24, 1996 |
N/A |
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| WADA Class View classifications | |||||||||
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N/A |
N/A |
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| More Information | |||||||||
| Patient Resources | |||||||||
| Professional Resources | |||||||||
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N/A |
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| Related Treatment Guide | |||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.