Comparing Symproic vs Trulance
| Symproic (naldemedine) | Trulance (plecanatide) |
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| Symproic (naldemedine) | Trulance (plecanatide) |
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Prescription only
Prescribed for Opioid-Induced Constipation. Symproic may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Irritable Bowel Syndrome with Constipation, Chronic Idiopathic Constipation. Trulance may also be used for purposes not listed in this medication guide. |
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| More about Symproic (naldemedine) | More about Trulance (plecanatide) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Symproic has an average rating of 6.4 out of 10 from a total of 34 ratings on Drugs.com. 56% of reviewers reported a positive effect, while 26% reported a negative effect. |
Trulance has an average rating of 6.1 out of 10 from a total of 279 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 34% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
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View all Symproic side effects |
View all Trulance side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Symproic prices |
View all Trulance prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
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N/A |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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11 hours |
N/A |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Summary unavailable. See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 179 drugs are known to interact with Symproic:
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A total of 1 drugs are known to interact with Trulance:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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March 23, 2017 |
January 19, 2017 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.