Saphris Alternatives Compared
| Saphris (asenapine) | Caplyta (lumateperone) | Lybalvi (olanzapine / samidorphan) |
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| Saphris (asenapine) | Caplyta (lumateperone) | Lybalvi (olanzapine / samidorphan) |
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Prescription only
Prescribed for Bipolar Disorder, Schizophrenia. Saphris may also be used for purposes not listed in this medication guide. |
Prescription only
Caplyta is an atypical antipsychotic that is used to treat adults with schizophrenia or depression associated with bipolar disorder. Sleepiness is the most common side effect and it should not be... View more |
Prescription only
Prescribed for Bipolar Disorder, Schizophrenia. Lybalvi may also be used for purposes not listed in this medication guide. |
Related suggestions Schizophrenia
Popular comparisons
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| More about Saphris (asenapine) | More about Caplyta (lumateperone) | More about Lybalvi (olanzapine / samidorphan) | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Saphris has an average rating of 7.4 out of 10 from a total of 318 ratings on Drugs.com. 69% of reviewers reported a positive effect, while 17% reported a negative effect. |
Caplyta has an average rating of 6.6 out of 10 from a total of 183 ratings on Drugs.com. 55% of reviewers reported a positive effect, while 29% reported a negative effect. |
Lybalvi has an average rating of 8.0 out of 10 from a total of 16 ratings on Drugs.com. 73% of reviewers reported a positive effect, while 7% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||||||||||
View all Saphris side effects |
View all Caplyta side effects |
View all Lybalvi side effects |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Saphris prices |
View all Caplyta prices |
View all Lybalvi prices |
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| Dosage Forms | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Other asenapine brands include: Secuado |
N/A |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||||||||||
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24 hours |
18 hours |
54 hours (empirically) |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 647 drugs are known to interact with Saphris:
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A total of 602 drugs are known to interact with Caplyta:
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A total of 699 drugs are known to interact with Lybalvi:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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August 13, 2009 |
December 20, 2019 |
May 28, 2021 |
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| WADA Class View classifications | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| Related Treatment Guide | ||||||||||||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.