Comparing Repatha vs Wegovy
| Repatha (evolocumab) | Wegovy (semaglutide) |
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| Repatha (evolocumab) | Wegovy (semaglutide) |
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Prescription only
Repatha is a PCSK9 inhibitor that may be used to reduce LDL-C levels in people with primary hyperlipidemia and HoFH, and also to reduce the risk of cardiovascular events in adults with established... View more |
Prescription only
Prescribed for Weight Loss (Obesity/Overweight), Cardiovascular Risk Reduction. Wegovy may also be used for purposes not listed in this medication guide. |
Related suggestions Cardiovascular Risk Reduction
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| More about Repatha (evolocumab) | More about Wegovy (semaglutide) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Repatha has an average rating of 5.4 out of 10 from a total of 705 ratings on Drugs.com. 40% of reviewers reported a positive effect, while 44% reported a negative effect. |
Wegovy has an average rating of 7.6 out of 10 from a total of 506 ratings on Drugs.com. 66% of reviewers reported a positive effect, while 14% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Repatha side effects |
View all Wegovy side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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N/A |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Repatha prices |
View all Wegovy prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
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N/A |
Other semaglutide brands include: Ozempic, Rybelsus | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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408 hours |
168 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Summary unavailable. See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 3 drugs are known to interact with Repatha:
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A total of 273 drugs are known to interact with Wegovy:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
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No known disease interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| First Approval Date | |||||||||||||||||
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August 27, 2015 |
N/A |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.