Comparing Relistor vs Symproic
| Relistor (methylnaltrexone) | Symproic (naldemedine) |
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| Relistor (methylnaltrexone) | Symproic (naldemedine) |
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Prescription only
Prescribed for Opioid-Induced Constipation, Constipation - Chronic, Constipation - Drug Induced. Relistor may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Opioid-Induced Constipation. Symproic may also be used for purposes not listed in this medication guide. |
Related suggestions Opioid-Induced Constipation
Popular comparisons
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| More about Relistor (methylnaltrexone) | More about Symproic (naldemedine) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Relistor has an average rating of 6.6 out of 10 from a total of 61 ratings on Drugs.com. 59% of reviewers reported a positive effect, while 31% reported a negative effect. |
Symproic has an average rating of 6.4 out of 10 from a total of 34 ratings on Drugs.com. 56% of reviewers reported a positive effect, while 26% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Relistor side effects |
View all Symproic side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Relistor prices |
View all Symproic prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
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N/A |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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8 hours |
11 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category B
No proven risk in humans
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 24 drugs are known to interact with Relistor:
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A total of 179 drugs are known to interact with Symproic:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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April 24, 2008 |
March 23, 2017 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.