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Premarin Vaginal Alternatives Compared

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Premarin Vaginal Remove Premarin Vaginal from your drug comparison Estradiol Remove Estradiol from your drug comparison Premarin Remove Premarin from your drug comparison
View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Premarin Vaginal conjugated estrogens Remove Premarin Vaginal from your drug comparison Estradiol Remove Estradiol from your drug comparison Premarin conjugated estrogens Remove Premarin from your drug comparison

Prescribed for Atrophic Vaginitis, Atrophic Urethritis, Postmenopausal Symptoms. Premarin Vaginal may also be used for purposes not listed in this medication guide.

Estradiol is a synthetic form of estrogen that may be given to women for a number of different indications, including the relief of menopausal symptoms or low estrogen levels. Its use is associated... View more

Prescribed for Atrophic Vaginitis, Atrophic Urethritis, Abnormal Uterine Bleeding, Breast Cancer - Palliative, Hypoestrogenism, Oophorectomy, Osteoporosis, Postmenopausal Symptoms, Primary Ovarian... View more

Prescription only

Prescription only

Prescription only

Ratings & Reviews

View all 13 reviews

View all 386 reviews

View all 70 reviews

Drug Class

Side Effects

See the full Premarin Vaginal side effects document.

Commonly reported side effects include: cerebrovascular accident, infection, malignant neoplasm of breast, endometrium disease, headache, mastalgia.

See the full estradiol side effects document.

See the full Premarin side effects document.

Pricing and Coupons

* Prices are without insurance
Quantity 30 gram(s)
Dosage 0.625 mg/g
Per Unit* $14.38
Cost* $431.28

View all Premarin Vaginal prices

Quantity 50 each
Dosage 1 mg
Per Unit* $0.37
Cost* $18.62

View all estradiol prices

Quantity 10 tablet
Dosage 0.625 mg
Per Unit* $3.48
Cost* $34.82

View all Premarin prices

Get free Discount Card

Get free Discount Card

Get free Discount Card

Generic Availability

No

Yes (this medicine)

No

Dosage Form(s) Available
  • Vaginal cream with applicator
  • Intramuscular solution
  • Oral tablet
  • Oral tablet

Brand Names

N/A

 Alora, Climara, Delestrogen, Depo-Estradiol, Divigel, Dotti, Elestrin, Estra Pellets, Estrace, Estraderm, Estradiol Patch, Estrogel, Evamist, Femring, Lyllana, Menostar, Minivelle, Vivelle-Dot View more Other conjugated estrogens brands include: Premarin Intravenous

Half Life

The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

8 hours

16 hours

N/A

CSA Schedule**

View glossary of terms.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category
X
Category X Not for use in pregnancy

See the full Pregnancy Warnings document.
X
Category X Not for use in pregnancy

See the full Pregnancy Warnings document.
X
Category X Not for use in pregnancy

See the full Pregnancy Warnings document.

FDA Alerts

FDA Alerts (1)

FDA Alerts (2)

FDA Alerts (1)

Drug Interactions

A total of 132 drugs are known to interact with Premarin Vaginal:

  • 7 major drug interactions (18 brand and generic names)
  • 111 moderate drug interactions (510 brand and generic names)
  • 14 minor drug interactions (38 brand and generic names)

A total of 298 drugs are known to interact with estradiol:

  • 7 major drug interactions (18 brand and generic names)
  • 271 moderate drug interactions (1001 brand and generic names)
  • 20 minor drug interactions (67 brand and generic names)

A total of 201 drugs are known to interact with Premarin:

  • 7 major drug interactions (18 brand and generic names)
  • 175 moderate drug interactions (686 brand and generic names)
  • 19 minor drug interactions (56 brand and generic names)

Alcohol/Food/Lifestyle Interactions

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

Disease Interactions

First Approval Date

N/A

July 23, 1975

May 08, 1942

WADA Class

View World Anti-Doping Agency classifications.

N/A

N/A

N/A

More Information

Consumer Resources

Professional Resources

Related Treatment Guide

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer