Comparing Paxil vs Trazodone
Paxil | Trazodone |
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Paxil (paroxetine) | Trazodone |
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Prescription only
Paxil may be used for the treatment of depression, anxiety, or post-traumatic stress disorder. It should be tapered off slowly on discontinuation. Prescribed for Anxiety and Stress, Dysautonomia... View more |
Prescription only
Trazodone is mostly used for its sleep-inducing effects (an off-label indication) rather than as an antidepressant. Only generic forms are available which makes it a lot cheaper than some other... View more |
Related suggestions Depression
Major Depressive Disorder
Popular comparisons
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More about Paxil (paroxetine) | More about Trazodone | ||||||||||||||||
Ratings & Reviews | |||||||||||||||||
Paxil has an average rating of 7.0 out of 10 from a total of 951 ratings on Drugs.com. 62% of reviewers reported a positive effect, while 20% reported a negative effect. |
Trazodone has an average rating of 6.3 out of 10 from a total of 1409 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 31% reported a negative effect. |
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Drug Class | |||||||||||||||||
Side Effects | |||||||||||||||||
See also: Paxil side effects in more detail. |
See also: trazodone side effects in more detail. |
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Generic Availability | |||||||||||||||||
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Paxil prices |
View all trazodone prices |
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Dosage Forms Available | |||||||||||||||||
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Brand Names | |||||||||||||||||
Other paroxetine brands include: Brisdelle, Paxil CR |
N/A |
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Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
21 hours |
7.5 hours |
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CSA Schedule ** View glossary of terms | |||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | |||||||||||||||||
Category D
Positive evidence of risk
Excluding Brisdelle
Category X
Not for use in pregnancy
Brisdelle See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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Drug Interactions | |||||||||||||||||
A total of 505 drugs are known to interact with Paxil:
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A total of 651 drugs are known to interact with trazodone:
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Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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Disease Interactions | |||||||||||||||||
First Approval Date | |||||||||||||||||
December 29, 1992 |
December 24, 1981 |
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WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
N/A |
N/A |
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More Information | |||||||||||||||||
Patient resources | |||||||||||||||||
Professional Resources | |||||||||||||||||
Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.