Novolog Alternatives Compared
| Novolog (insulin aspart) | Ozempic (semaglutide) | Rybelsus (semaglutide) |
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| Novolog (insulin aspart) | Ozempic (semaglutide) | Rybelsus (semaglutide) |
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Prescription only
Prescribed for Type 2 Diabetes, Diabetes - Type 1, Diabetic Ketoacidosis, Nonketotic Hyperosmolar Syndrome. Novolog may also be used for purposes not listed in this medication guide. |
Prescription only
Ozempic lowers blood sugar levels by mimicking the effects of GLP-1, a naturally occurring hormone that stimulates insulin secretion and lowers glucagon secretion from the liver. It is... View more |
Prescription only
Rybelsus (semaglutide) is an oral medicine that can be used as a first-line medication to improve blood sugar control in adults over the age of 18 with type 2 diabetes. It works by mimicking the... View more |
Related suggestions Type 2 Diabetes
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| More about Novolog (insulin aspart) | More about Ozempic (semaglutide) | More about Rybelsus (semaglutide) | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Novolog has an average rating of 5.5 out of 10 from a total of 32 ratings on Drugs.com. 31% of reviewers reported a positive effect, while 34% reported a negative effect. |
Ozempic has an average rating of 6.7 out of 10 from a total of 1566 ratings on Drugs.com. 52% of reviewers reported a positive effect, while 23% reported a negative effect. |
Rybelsus has an average rating of 6.5 out of 10 from a total of 308 ratings on Drugs.com. 49% of reviewers reported a positive effect, while 22% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||||||||||
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View all Novolog side effects |
View all Ozempic side effects |
View all Rybelsus side effects |
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| Drug Class | ||||||||||||||||||||||||||
| Generic Availability | ||||||||||||||||||||||||||
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N/A |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Novolog prices |
View all Ozempic prices |
View all Rybelsus prices |
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| Dosage Forms | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Other insulin aspart brands include: Fiasp, Kirsty, Merilog, Merilog SoloStar, NovoLog FlexPen, NovoLog PenFill, ReliOn NovoLog | Other semaglutide brands include: Rybelsus, Wegovy | Other semaglutide brands include: Ozempic, Wegovy | ||||||||||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||||||||||
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1.5 hours |
168 hours |
168 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category B
No proven risk in humans
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 396 drugs are known to interact with Novolog:
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A total of 275 drugs are known to interact with Ozempic:
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A total of 275 drugs are known to interact with Rybelsus:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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June 07, 2000 |
N/A |
September 20, 2019 |
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| WADA Class View classifications | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| Related Treatment Guide | ||||||||||||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.