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Medications for Nonketotic Hyperosmolar Syndrome

Drugs associated with Nonketotic Hyperosmolar Syndrome

The following drugs and medications are in some way related to, or used in the treatment of this condition.

What is Nonketotic Hyperosmolar Syndrome: Nonketotic Hyperosmolar Syndrome is a complication seen in diabetes mellitus in which very marked hyperglycemia occurs (such as levels exceeding 800 mg/dL), causing osmotic shifts in water in brain cells, and resulting in coma. It can be fatal or lead to permanent neurologic damage. Ketoacidosis does not occur in these cases.

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Popularity
insulin regular Rx/OTC B N X Add review Add

Generic name: insulin regular systemic

Brand names:  Humulin R, Novolin R

Drug class: insulin

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts

 
Humulin R Rx/OTC B N X Add review Add

Generic name: insulin regular systemic

Drug class: insulin

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Novolin R Rx/OTC B N X Add review Add

Generic name: insulin regular systemic

Drug class: insulin

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Humalog Rx B N X Add review Add

Generic name: insulin lispro systemic

Drug class: insulin

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
Humalog KwikPen Rx B N X Add review Add

Generic name: insulin lispro systemic

Drug class: insulin

For consumers: dosage, interactions, side effects

 
insulin lispro Rx B N X Add review Add

Generic name: insulin lispro systemic

Brand names:  Humalog, Humalog KwikPen

Drug class: insulin

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
insulin aspart Rx B N X Add review Add

Generic name: insulin aspart systemic

Brand names:  Novolog, NovoLog FlexPen, NovoLog PenFill

Drug class: insulin

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Novolog Rx B N X Add review Add

Generic name: insulin aspart systemic

Drug class: insulin

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph

 
NovoLog FlexPen Rx B N X Add review Add

Generic name: insulin aspart systemic

Drug class: insulin

For consumers: dosage, interactions, side effects

 
NovoLog PenFill Rx B N X Add review Add

Generic name: insulin aspart systemic

Drug class: insulin

For consumers: dosage, interactions, side effects

 
Apidra Rx C N X Add review Add

Generic name: insulin glulisine systemic

Drug class: insulin

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
Apidra Solostar Rx C N X Add review Add

Generic name: insulin glulisine systemic

Drug class: insulin

For consumers: dosage, interactions, side effects

 
insulin glulisine Rx C N X Add review Add

Generic name: insulin glulisine systemic

Brand names:  Apidra, Apidra Solostar

Drug class: insulin

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

 
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Legend

Off Label This medication may not be approved by the FDA for the treatment of this condition.
Prescription Only / Over the Counter
Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Pregnancy
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act Schedule
N The drug is not subject to the Controlled Substances Act.
1 The drug has a high potential for abuse. The drug has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use of the drug under medical supervision.
2 The drug has a high potential for abuse. The drug has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse of the drug may lead to severe psychological or physical dependence.
3 The drug has a potential for abuse less than the drugs in schedules 1 and 2. The drug has a currently accepted medical use in treatment in the United States. Abuse of the drug may lead to moderate or low physical dependence or high psychological dependence.
4 The drug has a low potential for abuse relative to the drugs in schedule 3. The drug has a currently accepted medical use in treatment in the United States. Abuse of the drug may lead to limited physical dependence or psychological dependence relative to the drugs in schedule 3.
5 The drug has a low potential for abuse relative to the drugs in schedule 4. The drug has a currently accepted medical use in treatment in the United States. Abuse of the drug may lead to limited physical dependence or psychological dependence relative to the drugs in schedule 4.
Alcohol
X Interacts with Alcohol.

Synonym(s): Diabetic Hyperglycemic Hyperosmolar Coma; HONK, hyperosmolar non-ketotic coma; NKHHC; Nonketotic Hyperglycemic Hyperosmolar Coma

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