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Comparing Humalog vs Novolog

View side-by-side comparisons of medication uses, ratings, cost, side effects, interactions and more.
Humalog Remove Humalog from your drug comparison Novolog Remove Novolog from your drug comparison
View side-by-side comparisons of medication uses, ratings, cost, side effects, interactions and more.
Humalog insulin lispro Remove Humalog from your drug comparison Novolog insulin aspart Remove Novolog from your drug comparison

Prescribed for Diabetes - Type 2, Diabetes - Type 1, Diabetic Ketoacidosis, Nonketotic Hyperosmolar Syndrome. Humalog may also be used for purposes not listed in this medication guide.

Prescribed for Diabetes - Type 2, Diabetes - Type 1, Diabetic Ketoacidosis, Nonketotic Hyperosmolar Syndrome. Novolog may also be used for purposes not listed in this medication guide.

Prescription only

Prescription only

Ratings & Reviews

Recent helpful reviews
7.6
12 Reviews

For Diabetes, Type 2: Significant weight gain (10%) very soon after starting Humalog. Not a powerful reducer of sugar like I would have expected for the frequency and cost.

6

For Diabetes, Type 2: Good for treating post-meal blood sugar spikes.

8
7.0
13 Reviews

For Diabetes, Type 1: Novolog works very well and very fast (3-5) hours in lowering sugar levels but for those w/out insurance be wary Novolog is very expensive, espicially when you have to couple the insulin w/ another slow-acting, such as Lantus. Together these are very effective however.

8

For Diabetes, Type 1: I have been a diabetic since I was 9 months old and still continue to use Novalog to this day and have never had any problems with the medication.

10

View all 12 reviews

View all 13 reviews

Drug Class

Side Effects

See the full Humalog side effects document.

Common side effects include: hypoglycemia.

See the full Novolog side effects document.

Pricing and Coupons

* Prices are without insurance
Quantity 3 mL
Dosage 100 units/mL
Per Unit* $31.51
Cost* $94.53

View all Humalog prices and generic prices

Quantity 10 mL
Dosage 100 units/mL
Per Unit* $31.06
Cost* $310.59

View all Novolog prices

Get free Discount Card

Get free Discount Card

Generic Availability

Yes

No

Dosage Form(s) Available
  • Injectable solution
  • Subcutaneous solution
  • Injectable solution
  • Subcutaneous solution

Brand Names
Other insulin lispro brands include: Admelog, Humalog Junior KwikPen, Humalog KwikPen Other insulin aspart brands include: Fiasp, NovoLog FlexPen, NovoLog PenFill

Half Life

The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

1 hour

1.5 hours

CSA Schedule**

View glossary of terms.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category
B
Category B No proven risk in humans

See the full Pregnancy Warnings document.
B
Category B No proven risk in humans

See the full Pregnancy Warnings document.

FDA Alerts

FDA Alerts (1)

FDA Alerts (2)

Drug Interactions

A total of 873 drugs are known to interact with Humalog:

  • 19 major drug interactions (43 brand and generic names)
  • 762 moderate drug interactions (5083 brand and generic names)
  • 92 minor drug interactions (640 brand and generic names)

A total of 873 drugs are known to interact with Novolog:

  • 19 major drug interactions (43 brand and generic names)
  • 762 moderate drug interactions (5083 brand and generic names)
  • 92 minor drug interactions (640 brand and generic names)

Alcohol/Food/Lifestyle Interactions
  • Talk to your doctor before using alcohol together with insulin lispro. Alcohol may affect blood... View more
  • Talk to your doctor before using alcohol together with insulin aspart. Alcohol may affect blood... View more

Disease Interactions

First Approval Date

June 14, 1996

June 07, 2000

WADA Class

View World Anti-Doping Agency classifications.

N/A

N/A

More Information

Consumer Resources

Professional Resources

Related Treatment Guide

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

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