Comparing Nardil vs Sertraline

For Depression: I've been on Nardil for 30 years after trying a bunch of other non-MAOI meds. It has been the ONLY anti-depressant that has worked for me! For reasons too long to explain, I had to go off Nardil about 10 years ago, and I became SO sick! I had nausea 24/7 for almost 6 months and obviously, was getting more and more depressed! We thought I would start to feel better after some time until finally, I couldn't take it any longer. Within the first 24 hrs of going back on Nardil, I started to feel physically better. A year or two later I tried to go off Nardil again. During a 6 month period, I was only able to wean off 1 of 3 pills, but I was sick the entire time! The moment I take even a half a pill, I'm not sick! Unfortunately, I am physically not able to go off Nardil even if I wanted to! I just hope that I won't ever HAVE to go off Nardil for health reasons because I will just be sick and depressed! Has anyone else experienced that or similar reaction to going off Nardil?

For Depression: Hello, On 29 July 2020 I was called by a sympathetic and capable mental health pharmacist for the UK NHS. She said the NHS has been *officially told* that Nardil will be discontinued “in the near future”. The NHS must safely transfer all UK patients to other treatments in the months ahead. We both acknowledged that MAOIs are often a last-resort—I'd trialled some 6–8 medications before Nardil, over ten years. The clinician was obliged to ask which of those failed meds had shown the most positives for me, or fewest side-effects. After feeling steady on Nardil for 10 years, I don't recall which earlier meds were least worst(!). But it’s discouraging. I asked about Parnate, but it seems unavailable to UK prescribers. I don’t have the whole story. Do ask your doctor or pharmacist very soon. And remember it’s unwise to change medicines or cease Nardil abruptly. Thank you and best wishes!

For Anxiety and Stress: I have decided to help myself. Today is my third day of Sertraline at 7am every morning: Weird lump sensation in my throat coupled with sicky feeling in tummy. I've totally lost my appetite by midday, forcing myself to eat. By midday I'm yawning a lot, a pretty tired and achey. By evening I am sleepy and drowsy. The main thing above all that I have noticed is that I feel flat, which is not a bad thing at all. Just days before I went on these meds I was constantly crying, shaking, wanting to my life to be over. I couldn't have a moment to myself without thinking negative thoughts. I had some bad news this morning from my energy provider which would normally send me into melt down, but I handled it with calmness. Very surprised and proud of myself. Bottom line: I'm bracing myself for side effects to worsen, but fingers crossed they don't. Right now they are certainly manageable and I'm glad I didn't let the reviews put me off.

For Anxiety and Stress: Started Zoloft 15days ago and have been having a tough time with the up and downs. The past two day’s have been bad with lots of anxiety, and shaking with lots of crying on the floor. The doctors warned me of these symptoms and encouraged me to be strong and that it will get better with time and to trust its the process as it balancing me out. I’m not having suicidal thoughts anymore so that’s a relief. My appetite has surely decreased although it seems that smoking a little marijuana helped me with that but would prefer not to have to smoke to eat. I should feel grateful that I’m actually feeling something again even if it hurts because nothings is as bad as the place I was at — I look forward to happy days again. Stay strong