Comparing Metronidazole vs Nitrofurantoin
| Metronidazole | Nitrofurantoin |
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| Metronidazole | Nitrofurantoin |
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Prescription only
Metronidazole treats T. vaginalis infections (both partners should be treated simultaneously) and amebic infections. It is also effective against serious anaerobic bacterial infections affecting the... View more |
Prescription only
Nitrofurantoin effectively treats urinary tract infections caused by E. coli and S. saprophyticus with low bacterial resistance risk. It's also used for UTI prophylaxis at low doses. Common side... View more |
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| More about Metronidazole | More about Nitrofurantoin | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Metronidazole has an average rating of 6.0 out of 10 from a total of 2434 ratings on Drugs.com. 44% of reviewers reported a positive effect, while 29% reported a negative effect. |
Nitrofurantoin has an average rating of 4.5 out of 10 from a total of 1895 ratings on Drugs.com. 29% of reviewers reported a positive effect, while 52% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Metronidazole side effects |
View all Nitrofurantoin side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Metronidazole prices |
View all Nitrofurantoin prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Flagyl, Flagyl 375, Flagyl IV, Likmez, Metro, Metro IV | Furadantin, Macrobid, Macrodantin | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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20 hours |
1 hour |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category B
No proven risk in humans
See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 395 drugs are known to interact with Metronidazole:
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A total of 226 drugs are known to interact with Nitrofurantoin:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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July 18, 1963 |
February 06, 1953 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.