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Comparing Levofloxacin vs Metronidazole

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Levofloxacin Remove Levofloxacin from your drug comparison Metronidazole Remove Metronidazole from your drug comparison
View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Levofloxacin Remove Levofloxacin from your drug comparison Metronidazole Remove Metronidazole from your drug comparison

Levofloxacin treats a wide range of bacterial infections; however, it can cause some very severe and potentially irreversible side effects such as tendonitis or tendon rupture and should only be used... View more

Metronidazole is an antibiotic that is particularly effective at treating infections caused by susceptible anaerobic bacteria and parasites. Avoid alcohol while taking metronidazole and for three... View more

Prescription only

Prescription only

Ratings & Reviews

View all 665 reviews

View all 2092 reviews

Drug Class

Side Effects

See the full levofloxacin side effects document.

See the full metronidazole side effects document.

Pricing and Coupons

* Prices are without insurance
Quantity 2 tablet
Dosage 500 mg
Per Unit* $3.58
Cost* $7.15

View all levofloxacin prices

Quantity 1 tablet
Dosage 500 mg
Per Unit* $8.44 - $9.72
Cost* $8.44 - $9.72

View all metronidazole prices

Get free Discount Card

Get free Discount Card

Generic Availability

Yes (this medicine)

Yes (this medicine)

Dosage Form(s) Available
  • Intravenous solution
  • Oral solution
  • Oral tablet
  • Intravenous solution
  • Oral capsule
  • Oral tablet

Brand Names
Levaquin Flagyl, Flagyl 375, Flagyl IV, Metro, Metro IV

Half Life

The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

6 hours

20 hours

CSA Schedule**

View glossary of terms.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category
C
Category C Risk cannot be ruled out

See the full Pregnancy Warnings document.
B
Category B No proven risk in humans

See the full Pregnancy Warnings document.

FDA Alerts

FDA Alerts (7)

FDA Alerts (3)

Drug Interactions

A total of 454 drugs are known to interact with levofloxacin:

  • 103 major drug interactions (469 brand and generic names)
  • 300 moderate drug interactions (2440 brand and generic names)
  • 51 minor drug interactions (135 brand and generic names)

A total of 325 drugs are known to interact with metronidazole:

  • 10 major drug interactions (30 brand and generic names)
  • 132 moderate drug interactions (473 brand and generic names)
  • 183 minor drug interactions (580 brand and generic names)

Alcohol/Food/Lifestyle Interactions
  • When levoFLOXacin as the oral solution is given with enteral (tube) feedings, levoFLOXacin may not... View more
  • Consumption of alcoholic beverages or products containing alcohol or propylene glycol during... View more

Disease Interactions

First Approval Date

December 20, 1996

July 18, 1963

WADA Class

View World Anti-Doping Agency classifications.

N/A

N/A

More Information

Consumer Resources

Professional Resources

Related Treatment Guide

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer