Comparing Lamotrigine vs Divalproex Sodium
| Lamotrigine | Divalproex sodium |
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| Lamotrigine | Divalproex sodium |
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Prescription only
Lamotrigine is used to decrease the frequency and severity of seizures in some types of epilepsy and also to stabilize mood in bipolar I disorder. It is an oral tablet that is taken once or twice a... View more |
Prescription only
Divalproex may be used for the treatment of absence or partial seizures, as a preventive treatment for migraines, and to treat mania associated with bipolar disorder. Divalproex may adversely and... View more |
Related suggestions Migraine Prevention (Migraine Prophylaxis)
Seizures
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| More about Lamotrigine | More about Divalproex sodium | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Lamotrigine has an average rating of 7.8 out of 10 from a total of 1844 ratings on Drugs.com. 73% of reviewers reported a positive effect, while 15% reported a negative effect. |
Divalproex sodium has an average rating of 6.6 out of 10 from a total of 512 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 23% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Lamotrigine side effects |
View all Divalproex sodium side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Lamotrigine prices |
View all Divalproex sodium prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Lamictal, Lamictal CD, Lamictal ODT, Lamictal XR, Subvenite | Depakote, Depakote ER, Depakote Sprinkles | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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25.7 hours |
16 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category D
Positive evidence of risk
When Treating Epilepsy And Manic Episodes Associated With Bipolar Disorder
Category X
Not for use in pregnancy
When Treating Migraine See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 287 drugs are known to interact with Lamotrigine:
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A total of 426 drugs are known to interact with Divalproex sodium:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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December 27, 1994 |
March 10, 1983 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Lamictal
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Depakote
Depakote is used to treat various types of seizure disorders. Learn about side effects ...
Divalproex sodium
Divalproex sodium is used for bipolar disorder, borderline personality disorder, cyclothymic ...
Lithium
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Carbamazepine
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Risperidone
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.