Hydrochlorothiazide Alternatives Compared
| Hydrochlorothiazide | Lisinopril | Amlodipine |
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| Hydrochlorothiazide | Lisinopril | Amlodipine |
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Prescription only
Hydrochlorothiazide (HCTZ) may be used to relieve edema (fluid retention) and to lower high blood pressure. A headache, dizziness on standing, dehydration, skin reactions, and depletion of... View more |
Prescription only
Lisinopril can be used to treat high blood pressure and heart failure, and to increase survival following a heart attack. However, lisinopril may cause a persistent, dry, hacking cough which may... View more |
Prescription only
Amlodipine is a heart medication that may be used for the treatment of angina or to lower blood pressure but it can cause edema in the ankles or feet. Prescribed for High Blood Pressure, Raynaud's... View more |
Related suggestions High Blood Pressure (Hypertension)
Popular comparisons
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| More about Hydrochlorothiazide | More about Lisinopril | More about Amlodipine | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Hydrochlorothiazide has an average rating of 5.2 out of 10 from a total of 186 ratings on Drugs.com. 34% of reviewers reported a positive effect, while 38% reported a negative effect. |
Lisinopril has an average rating of 5.0 out of 10 from a total of 628 ratings on Drugs.com. 34% of reviewers reported a positive effect, while 44% reported a negative effect. |
Amlodipine has an average rating of 4.4 out of 10 from a total of 842 ratings on Drugs.com. 28% of reviewers reported a positive effect, while 53% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||||||||||
View all Hydrochlorothiazide side effects |
View all Lisinopril side effects |
View all Amlodipine side effects |
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| Drug Class | ||||||||||||||||||||||||||
| Generic Availability | ||||||||||||||||||||||||||
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Lower cost generic |
Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Hydrochlorothiazide prices |
View all Lisinopril prices |
View all Amlodipine prices |
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| Dosage Forms | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Aquazide H, Carozide, Diaqua, Esidrix, Ezide, Hydro Par, Inzirqo, Microzide | Prinivil, Qbrelis, Zestril | Katerzia, Norliqva, Norvasc | ||||||||||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||||||||||
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12 hours |
16.4 hours |
35 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category B
No proven risk in humans
See the full pregnancy warnings document. |
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 472 drugs are known to interact with Hydrochlorothiazide:
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A total of 403 drugs are known to interact with Lisinopril:
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A total of 545 drugs are known to interact with Amlodipine:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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February 12, 1959 |
December 29, 1987 |
July 31, 1992 |
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| WADA Class View classifications | ||||||||||||||||||||||||||
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N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
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| Related Treatment Guide | ||||||||||||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.