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Hydrochlorothiazide Alternatives Compared

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Hydrochlorothiazide Remove Hydrochlorothiazide from your drug comparison Lisinopril Remove Lisinopril from your drug comparison Amlodipine Remove Amlodipine from your drug comparison
View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Hydrochlorothiazide Remove Hydrochlorothiazide from your drug comparison Lisinopril Remove Lisinopril from your drug comparison Amlodipine Remove Amlodipine from your drug comparison

Hydrochlorothiazide may be used to relieve edema and in the treatment of high blood pressure but may not be suitable for some people including those with sulfonamide allergies. Prescribed for High... View more

Lisinopril can be used to treat high blood pressure, heart failure, and to increase survival following a heart attack. However, the development of a dry, hacking cough attributable to the drug may... View more

Amlodipine may be used for the treatment of angina or to lower blood pressure but can cause edema in the feet. Prescribed for Raynaud's Syndrome, High Blood Pressure, Coronary Artery Disease, Angina,... View more

Prescription only

Prescription only

Prescription only

Ratings & Reviews

View all 156 reviews

View all 561 reviews

View all 596 reviews

Drug Class

Side Effects

See the full hydrochlorothiazide side effects document.

Commonly reported side effects include: dizziness, hypotension, hyperkalemia, increased blood urea nitrogen, increased serum creatinine.

See the full lisinopril side effects document.

Commonly reported side effects include: edema.

See the full amlodipine side effects document.

Pricing and Coupons

* Prices are without insurance
Quantity 6 tablet
Dosage 25 mg
Per Unit* $1.60
Cost* $9.58

View all hydrochlorothiazide prices

Quantity 10 tablet
Dosage 20 mg
Per Unit* $0.61
Cost* $6.05

View all lisinopril prices

Quantity 100 tablet
Dosage 10 mg
Per Unit* $0.49
Cost* $49.34

View all amlodipine prices

Get free Discount Card

Get free Discount Card

Get free Discount Card

Generic Availability

Yes (this medicine)

Yes (this medicine)

Yes (this medicine)

Dosage Form(s) Available
  • Oral capsule
  • Oral tablet
  • Oral tablet
  • Oral tablet

Brand Names
Aquazide H, Carozide, Diaqua, Esidrix, Ezide, Hydro Par, Microzide Prinivil, Qbrelis, Zestril Katerzia, Norvasc

Half Life

The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

12 hours

16.4 hours

35 hours

CSA Schedule**

View glossary of terms.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category
B
Category B No proven risk in humans

See the full Pregnancy Warnings document.
D
Category D Positive evidence of risk

See the full Pregnancy Warnings document.
C
Category C Risk cannot be ruled out

See the full Pregnancy Warnings document.

FDA Alerts

FDA Alerts (2)

FDA Alerts (1)

FDA Alerts (1)

Drug Interactions

A total of 421 drugs are known to interact with hydrochlorothiazide:

  • 13 major drug interactions (34 brand and generic names)
  • 371 moderate drug interactions (2147 brand and generic names)
  • 37 minor drug interactions (184 brand and generic names)

A total of 366 drugs are known to interact with lisinopril:

  • 37 major drug interactions (168 brand and generic names)
  • 299 moderate drug interactions (1414 brand and generic names)
  • 30 minor drug interactions (221 brand and generic names)

A total of 425 drugs are known to interact with amlodipine:

  • 19 major drug interactions (55 brand and generic names)
  • 375 moderate drug interactions (2466 brand and generic names)
  • 31 minor drug interactions (86 brand and generic names)

Alcohol/Food/Lifestyle Interactions
  • HydroCHLOROthiazide and alcohol may have additive effects in lowering your blood pressure. You may... View more
  • It is recommended that if you are taking lisinopril you should be advised to avoid moderately high... View more

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

Disease Interactions

First Approval Date

February 12, 1959

December 29, 1987

July 31, 1992

WADA Class

View World Anti-Doping Agency classifications.

N/A

N/A

More Information

Consumer Resources

Professional Resources

Related Treatment Guide

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer