Hydrochlorothiazide Alternatives Compared
| Hydrochlorothiazide | Lisinopril | Amlodipine |
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| Hydrochlorothiazide | Lisinopril | Amlodipine |
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Prescription only
Hydrochlorothiazide may be used to relieve edema and in the treatment of high blood pressure but may not be suitable for some people including those with sulfonamide allergies. Prescribed for High... View more |
Prescription only
Lisinopril can be used to treat high blood pressure and heart failure, and to increase survival following a heart attack. However, the development of a dry, hacking cough attributable to the drug may... View more |
Prescription only
Amlodipine is a heart medication that may be used for the treatment of angina or to lower blood pressure but it can cause edema in the ankles or feet. Prescribed for High Blood Pressure, Coronary... View more |
Related suggestions High Blood Pressure (Hypertension)
Popular comparisons
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| More about Hydrochlorothiazide | More about Lisinopril | More about Amlodipine | ||||||||||||||||||||||||
| Generic Status | ||||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Hydrochlorothiazide has an average rating of 5.1 out of 10 from a total of 183 ratings on Drugs.com. 33% of reviewers reported a positive effect, while 39% reported a negative effect. |
Lisinopril has an average rating of 5.0 out of 10 from a total of 620 ratings on Drugs.com. 34% of reviewers reported a positive effect, while 44% reported a negative effect. |
Amlodipine has an average rating of 4.1 out of 10 from a total of 804 ratings on Drugs.com. 25% of reviewers reported a positive effect, while 56% reported a negative effect. |
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| Side Effects | ||||||||||||||||||||||||||
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See also: hydrochlorothiazide side effects in more detail. |
Commonly reported side effects include:
See also: lisinopril side effects in more detail. |
Commonly reported side effects include:
See also: amlodipine side effects in more detail. |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all hydrochlorothiazide prices |
View all lisinopril prices |
View all amlodipine prices |
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| Dosage Form(s) Available | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Aquazide H, Carozide, Diaqua, Esidrix, Ezide, Hydro Par, Microzide | Prinivil, Qbrelis, Zestril | Katerzia, Norliqva, Norvasc | ||||||||||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
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12 hours |
16.4 hours |
35 hours |
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| CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category B
No proven risk in humans
See the full pregnancy warnings document. |
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 453 drugs are known to interact with hydrochlorothiazide:
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A total of 392 drugs are known to interact with lisinopril:
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A total of 510 drugs are known to interact with amlodipine:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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| First Approval Date | ||||||||||||||||||||||||||
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February 12, 1959 |
December 29, 1987 |
July 31, 1992 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
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N/A |
N/A |
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| Related Treatment Guide | ||||||||||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.