Comparing Glipizide vs Tradjenta

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Glipizide	Tradjenta (linagliptin)	Enter another drug to compare

Glipizide

Tradjenta (linagliptin)

Prescription only

Glipizide may be used in the management of type 2 diabetes to maintain good blood glucose control; however, its effects may wear off with time. Prescribed for Type 2 Diabetes. Glipizide may also be... View more

Prescription only

Prescribed for Type 2 Diabetes. Tradjenta may also be used for purposes not listed in this medication guide.

More about Glipizide

More about Tradjenta (linagliptin)

Ratings & Reviews

Glipizide has an average rating of 6.5 out of 10 from a total of 75 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 28% reported a negative effect.

Tradjenta has an average rating of 3.5 out of 10 from a total of 74 ratings on Drugs.com. 22% of reviewers reported a positive effect, while 69% reported a negative effect.

View all 75 reviews

View all 74 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

Diarrhea (13.3%)
Weight gain (9.3%)
Nausea (8.0%)
Upset stomach (6.7%)
Dizziness (5.3%)
Headaches (5.3%)
Tremors (5.3%)

View all Glipizide side effects

Joint pain (14.9%)
Back pain (13.5%)
Dizziness (10.8%)
Headaches (9.5%)
Stomach pain (9.5%)
Tiredness (8.1%)
Weight gain (8.1%)

View all Tradjenta side effects

Drug Class

Sulfonylureas

Dipeptidyl peptidase 4 inhibitors

Generic Availability

Lower cost generic

Lower cost generic approved

Pricing and Coupons * Prices are without insurance

Quantity	50 each
Strength	10 mg
Per unit^*	$0.39
Cost^*	$19.54

View all Glipizide prices

Quantity	100 each
Strength	5 mg
Per unit^*	$18.78
Cost^*	$1,878.45

View all Tradjenta prices

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Dosage Forms

Oral tablet
Oral tablet, extended release

Oral tablet

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

4.3 hours

12 hours

CSA Schedule ¹ View glossary of CSA terms

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Category B No proven risk in humans

See the full pregnancy warnings document.

Drug Interactions

A total of 485 drugs are known to interact with Glipizide:

23 major drug interactions (59 brand and generic names)
443 moderate drug interactions (2379 brand and generic names)
19 minor drug interactions (116 brand and generic names)

A total of 349 drugs are known to interact with Tradjenta:

2 major drug interactions (5 brand and generic names)
346 moderate drug interactions (1653 brand and generic names)
1 minor drug interactions (10 brand and generic names)

Alcohol/Food/Lifestyle Interactions

Alcohol may affect blood glucose levels in patients with diabetes. Both hypoglycemia (low blood... View more

Alcohol may affect blood glucose levels in patients with diabetes. Both hypoglycemia (low blood... View more

Disease Interactions

Pancreatitis

First Approval Date

May 08, 1984

May 02, 2011

WADA Class View classifications

N/A

More Information

Patient Resources

Glipizide uses

Tradjenta uses

Professional Resources

Prescribing information

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Comparing Glipizide vs Tradjenta

See also:

Ozempic

Rybelsus

Mounjaro

Trulicity

Lantus

Tresiba

Victoza

Basaglar

Levemir

Novolog

Further information

Comparing Glipizide vs Tradjenta

See also:

Further information

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