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Glipizide and Headaches: What Users Say

Brand names: Glucotrol, GlipiZIDE XL, Glucotrol XL

Headaches: mentioned by 4 users (5.3%)

Based on user experiences from 75 Glipizide reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

diarrhea 13.3%
weight gain 9.3%
nausea 8.0%
upset stomach 6.7%
dizziness 5.3%
headaches 5.3%
tremors 5.3%
bloating 4.0%
stomach pain 4.0%

Reviews for Glipizide

Commonly mentioned side effects
  • SDe...
  • September 8, 2015

Glipizide for Type 2 Diabetes "I started taking Glipizide ER initially with instructions to take it only if my blood glucose level was 180 or higher. I did not have to take it every day, but took it several times a week. Then I was started having a hard time controlling my daily glucose levels. My Hg A1c was higher, so the instructions were changed to 2 in the a.m. and 1 at night. I purchased the medication from a different source and it was a larger pill with now Glipazide XL instead of ER. I have experienced a number of side effects and feel worse with it than before I started taking it. The longer I have taken it the worse I feel. I feel drugged, want to sleep all the time, have a slight headache, more thirsty, constipation on occasion, dry eyes, and more. Yuck!"

3 / 10
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119 Report
  • Sug...
  • Taken for less than 1 month
  • September 15, 2017

For Type 2 Diabetes "I just started using glipizide 5 mg 3 weeks ago in combination with metformin 1000 mg twice a day. It is a powerful medicine, as I noticed my sugar was 300, and 3 hours later, it was down to 100. My body was shaking, and my stomach was not feeling well. I was told to take medication and eat 30 minutes later, and then take metformin after the meal. Since my numbers didn't go much over 150, the doctor said we didn't need to up to the 10 mg a day she thought I would need after the 3 weeks. I was avoiding insulin and was prescribed glipizide, I realize I must start doing it without it. Just use one medication, or my stomach will suffer. I had a belly ache and later had to go to the toilet. I also have headaches and need more lotion since I am itchier."

10 / 10
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30 Report
  • pag...
  • August 10, 2014

Glipizide for Type 2 Diabetes "I had severe headaches, muscle aches, anxiety. I felt flushed, skin excessively warm. Dizziness, my eyeballs hurt. Nausea, vomiting, motion sickness, yes motion sickness."

3 / 10
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84 Report
  • Jep...
  • January 5, 2016

For Type 2 Diabetes "Severe stomach pain, nausea, headache. After I stopped taking this for a couple of weeks, my symptoms went away. Started taking it again. All the above came back."

4 / 10
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43 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.