Comparing Fluoxetine vs Sertraline
| Fluoxetine | Sertraline |
|
|---|
| Fluoxetine | Sertraline |
|
|||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Prescription only
Fluoxetine treats major depression (adults/children 8+), OCD (adults/children 7+), bulimia nervosa, and panic disorder. More likely to cause insomnia than drowsiness. There is a risk of serotonin... View more |
Prescription only
Sertraline is used to treat mood disorders such as depression, anxiety, OCD, PTSD, panic disorder, and premenstrual dysphoric disorder (PMDD). Headaches, nausea, diarrhea, weight loss, insomnia... View more |
Related suggestions Depression
Major Depressive Disorder
Anxiety and Stress
Panic Disorder
|
|||||||||||||||
| More about Fluoxetine | More about Sertraline | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
|
Fluoxetine has an average rating of 7.3 out of 10 from a total of 2254 ratings on Drugs.com. 66% of reviewers reported a positive effect, while 18% reported a negative effect. |
Sertraline has an average rating of 7.3 out of 10 from a total of 4607 ratings on Drugs.com. 64% of reviewers reported a positive effect, while 18% reported a negative effect. |
||||||||||||||||
| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Fluoxetine side effects |
View all Sertraline side effects |
||||||||||||||||
| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
|
Lower cost generic |
Lower cost generic |
||||||||||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Fluoxetine prices |
View all Sertraline prices |
||||||||||||||||
| Dosage Forms | |||||||||||||||||
|
|
||||||||||||||||
| Brand Names | |||||||||||||||||
| Prozac | Zoloft | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
|
210 hours |
66 hours |
||||||||||||||||
| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
|
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
||||||||||||||||
| Pregnancy Category | |||||||||||||||||
|
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
||||||||||||||||
| Drug Interactions | |||||||||||||||||
|
A total of 684 drugs are known to interact with Fluoxetine:
|
A total of 675 drugs are known to interact with Sertraline:
|
||||||||||||||||
| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
|
|
||||||||||||||||
| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
|
December 29, 1987 |
December 30, 1991 |
||||||||||||||||
| WADA Class View classifications | |||||||||||||||||
|
N/A |
N/A |
||||||||||||||||
| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
|
|
||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.