Comparing Estradiol vs Testosterone
| Estradiol | Testosterone |
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| Estradiol | Testosterone |
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Prescription only
Estradiol is used to treat menopause symptoms, vulvar/vaginal thinning, low estrogen levels, and to prevent osteoporosis. It may also be used in the palliative treatment of breast cancer and prostate... View more |
Prescription only
Prescribed for Hypogonadism - Male, Gender Affirming Hormone Therapy, Gender Dysphoria, Delayed Puberty - Male, Breast Cancer - Palliative, Klinefelter Syndrome, Postpartum Breast Pain. Testosterone... View more |
Related suggestions Gender Dysphoria
Gender Affirming Hormone Therapy
Popular comparisons
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| More about Estradiol | More about Testosterone | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Estradiol has an average rating of 5.8 out of 10 from a total of 599 ratings on Drugs.com. 46% of reviewers reported a positive effect, while 37% reported a negative effect. |
Testosterone has an average rating of 7.3 out of 10 from a total of 538 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 18% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Estradiol side effects |
View all Testosterone side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Estradiol prices |
View all Testosterone prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Alora, Climara, Delestrogen, Depo-Estradiol, Divigel, Dotti, Elestrin, Estra Pellets, Estrace, Estraderm, Estradiol Patch, Estrogel, Evamist, Femring, Lyllana, Menostar, Minivelle, Vivelle-Dot View more | Andro LA 200, Andro-Cyp 100, Andro-Cyp 200, Androderm, AndroGel, Aveed, Azmiro, Delatest, Depandro 100, Depo-Testosterone, Depotest, Duratest, Durathate 200, Everone, FIRST-Testosterone, FIRST-Testosterone MC, Fortesta, Histerone, Jatenzo, Kyzatrex, Natesto, Striant, Testim, Testo-100, Testo-200, Testopel, Testopel Pellets, Testro-LA, Tlando, Undecatrex, Vogelxo, Xyosted View more | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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16 hours |
2 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Moderate abuse potential
Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence. |
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| Pregnancy Category | |||||||||||||||||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 393 drugs are known to interact with Estradiol:
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A total of 191 drugs are known to interact with Testosterone:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
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| First Approval Date | |||||||||||||||||
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July 23, 1975 |
December 24, 1953 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.