Comparing Estradiol vs Premarin
| Estradiol | Premarin (conjugated estrogens) |
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| Estradiol | Premarin (conjugated estrogens) |
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Prescription only
Estradiol is a synthetic form of estrogen that may be given for several different indications, including the relief of menopausal symptoms or low estrogen levels caused by other conditions. Its use... View more |
Prescription only
Prescribed for Atrophic Vaginitis, Abnormal Uterine Bleeding, Atrophic Urethritis, Breast Cancer - Palliative, Hypoestrogenism, Oophorectomy, Osteoporosis, Postmenopausal Symptoms, Primary Ovarian... View more |
Related suggestions Postmenopausal Symptoms
Atrophic Vaginitis
Prostate Cancer
Oophorectomy
Popular comparisons
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| More about Estradiol | More about Premarin (conjugated estrogens) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Estradiol has an average rating of 5.8 out of 10 from a total of 587 ratings on Drugs.com. 46% of reviewers reported a positive effect, while 37% reported a negative effect. |
Premarin has an average rating of 7.7 out of 10 from a total of 84 ratings on Drugs.com. 70% of reviewers reported a positive effect, while 17% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Estradiol side effects |
View all Premarin side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Estradiol prices |
View all Premarin prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Alora, Climara, Delestrogen, Depo-Estradiol, Divigel, Dotti, Elestrin, Estra Pellets, Estrace, Estraderm, Estradiol Patch, Estrogel, Evamist, Femring, Lyllana, Menostar, Minivelle, Vivelle-Dot View more | Other conjugated estrogens brands include: Premarin Intravenous | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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16 hours |
N/A |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 374 drugs are known to interact with Estradiol:
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A total of 256 drugs are known to interact with Premarin:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
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| First Approval Date | |||||||||||||||||
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July 23, 1975 |
May 08, 1942 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.