Comparing Estradiol vs Premarin

For Postmenopausal Symptoms I love the effects of Estradiol Transdermal Patch on my severe hot flashes and mood swings. But because bathing water penetrates the glue and its difficult to get the patch to stay on more than 4-5 days. I've taped it on, placed a large bandaid over. Just anything to stretch out 7 days worth of use. This is a major issue with me because they only give you 4 patches a month. I've spoken with my pharmacist they suggested I contact the manufacturer. Does anyone else have this issue?

For Postmenopausal Symptoms I was very reluctant to use this method, but I must say that it works. My hot flashing has decreased to 1 hot flash per day. I now have moisture in my vagina again, which is naturally creamy like before my hysterectomy. I am very pleased.

For Postmenopausal Symptoms I am 57yrs. My sister in law mentioned that she took Premarin for 5 years with no side effects. I was intrigue, I never heard of this medication. I went to my doctor and asked for Premarin, she prescribed me 0.3mg. Wow, amazing results! No side effects. I just finished my 30 days’ supply, went back to my doctor; asked for a little higher dosage because I was still having hot flashes & vaginal dryness, so she prescribed another 30 days on 0.45. Of course, my doctor does not recommend this medication because all the possible side effects specially heart attack: I told her let me try and see how I feel. Now I will have one more month at .45mg, I will see what are the results. I will keep everyone posted.

For Postmenopausal Symptoms Hormone Replacement Therapy (HRT) - I took Prempro for two years after becoming menopausal at age 40. When it stopped working a year ago, I was changed to a daily combination of Premarin 1.25 and medroxyprogesterone 2.5. Without HRT I experience irritability and irrational rage, hot flashes, and a non-existent sex drive. The current HRT which includes Premarin, works very well for me. It is frustrating how difficult it is for a woman in her 40s to be taken seriously by the medical community for complaints of low libido. (Consider Viagra, etc. for men). Every year my doctors suggest I give up this medication therapy that increases my quality of life 100%. I'm 43 and so far I'm winning, but I expect that I will have to keep fighting.