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Comparing Estrace vs Estradiol

Estrace

estradiol

Estradiol

Prescribed for Atrophic Vaginitis, Postmenopausal Symptoms, Atrophic Urethritis, Hypoestrogenism, Oophorectomy, Breast Cancer - Palliative, Primary Ovarian Failure, Prostate Cancer. Estrace may also... more

Estradiol is a synthetic form of estrogen that may be given to women for a number of different indications, including the relief of menopausal symptoms or low estrogen levels. Its use is associated... more

Prescription only

Prescription only

Ratings & Reviews

Recent helpful reviews
7.4
10 Reviews

For Postmenopausal Symptoms Works good but my co-pay with Insurance is very expensive.

9
Anonymous

For Postmenopausal Symptoms Works great for vaginal atrophy. MD put me on 2 wks of 1mg nightly of vaginal estrace, followed by 1mg 2x a week. It's a bit messy so may opt for the Mona Lisa Touch laser for atrophy in the long run, but this does help greatly with lubrication and plumping atrophied vaginal tissues. I went into menopause at 30 due to surgical menopause so this made me feel more confident about myself sexually.

9
CityGal212
7.2
231 Reviews

For Postmenopausal Symptoms I love the effects of Estradiol Transdermal Patch on my severe hot flashes and mood swings. But because bathing water penetrates the glue and its difficult to get the patch to stay on more than 4-5 days. I've taped it on, placed a large bandaid over. Just anything to stretch out 7 days worth of use. This is a major issue with me because they only give you 4 patches a month. I've spoken with my pharmacist they suggested I contact the manufacturer. Does anyone else have this issue?

7
Realtor

For Postmenopausal Symptoms I was very reluctant to use this method, but I must say that it works. My hot flashing has decreased to 1 hot flash per day. I now have moisture in my vagina again, which is naturally creamy like before my hysterectomy. I am very pleased.

8
Ms. H, Dallas, TX

View all 10 reviews

View all 231 reviews

Drug Class

Side Effects

See the full Estrace side effects document.

Commonly reported side effects include: cerebrovascular accident, infection, malignant neoplasm of breast, endometrium disease, headache, and mastalgia.

See the full estradiol side effects document.

Pricing and Coupons

* Prices are without insurance
Quantity 30 tablet
Dosage 1 mg
Per Unit* $2.16 - $4.03
Cost* $64.85 - $120.88
View all Estrace prices
View generic prices
Quantity 50 each
Dosage 1 mg
Per Unit* $0.37
Cost* $18.62
View all estradiol prices

Get free Discount Card

Get free Discount Card

Generic Availability

Yes

Yes (this medicine)

Dosage Form(s) Available
  • Oral tablet
  • Intramuscular solution
  • Oral tablet

Brand Names
Other estradiol brands include: Alora, Climara, Delestrogen, Depo-Estradiol, Divigel, Elestrin, Estra Pellets, Estraderm, Estradiol Patch, Estrasorb, Estrogel, Evamist, Femring, Femtrace, Menostar, Minivelle, Oesclim, Oestradiol Implants, Oestrodose, Oestrogel, Oestrogel Pump-Pack, Organon Oestradiol, Oromone, Primogyn Depot, Progynova, Progynova TS, Provames, Sandrena, Systen, Thais, Thaissept, Vivelle, Vivelle-Dot, Zumenon more... Alora, Climara, Delestrogen, Depo-Estradiol, Divigel, Elestrin, Estra Pellets, Estrace, Estraderm, Estradiol Patch, Estrasorb, Estrogel, Evamist, Femring, Femtrace, Menostar, Minivelle, Oesclim, Oestradiol Implants, Oestrodose, Oestrogel, Oestrogel Pump-Pack, Organon Oestradiol, Oromone, Primogyn Depot, Progynova, Progynova TS, Provames, Sandrena, Systen, Thais, Thaissept, Vivelle, Vivelle-Dot, Zumenon more...

Half Life

The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

16 hours

16 hours

CSA Schedule**

View glossary of terms.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category
X
Category X Not for use in pregnancy

See the full Pregnancy Warnings document.
X
Category X Not for use in pregnancy

See the full Pregnancy Warnings document.

FDA Alerts

FDA Alerts (2)

FDA Alerts (2)

Drug Interactions

A total of 390 drugs are known to interact with Estrace:

  • 9 major drug interactions (23 brand and generic names)
  • 349 moderate drug interactions (1321 brand and generic names)
  • 32 minor drug interactions (93 brand and generic names)

A total of 390 drugs are known to interact with estradiol:

  • 9 major drug interactions (23 brand and generic names)
  • 349 moderate drug interactions (1321 brand and generic names)
  • 32 minor drug interactions (93 brand and generic names)

Alcohol/Food/Lifestyle Interactions

No results found - however, this does not necessarily mean no warnings exist. Always consult with your doctor or pharmacist.

No results found - however, this does not necessarily mean no warnings exist. Always consult with your doctor or pharmacist.

Disease Interactions

First Approval Date

July 23, 1975

July 23, 1975

WADA Class

View World Anti-Doping Agency classifications.

N/A

N/A

More Information

Consumer Resources

Professional Resources

Related Treatment Guide

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

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