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Drospirenone / ethinyl estradiol / levomefolate calcium Alternatives Compared

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Drospirenone / ethinyl estradiol / levomefolate calcium Mirena (levonorgestrel) Nexplanon (etonogestrel)
View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Drospirenone / ethinyl estradiol / levomefolate calcium Mirena (levonorgestrel) Nexplanon (etonogestrel)
Prescription only

Prescribed for Premenstrual Dysphoric Disorder, Birth Control, Polycystic Ovary Syndrome, Acne. Drospirenone / ethinyl estradiol / levomefolate calcium may also be used for purposes not listed in... View more

Prescription only

Prescribed for Heavy Menstrual Bleeding, Birth Control. Mirena may also be used for purposes not listed in this medication guide.

Prescription only

Prescribed for Birth Control. Nexplanon may also be used for purposes not listed in this medication guide.

Related suggestions
More about Drospirenone / ethinyl estradiol / levomefolate calcium More about Mirena (levonorgestrel) More about Nexplanon (etonogestrel)
Ratings & Reviews

Drospirenone / ethinyl estradiol / levomefolate calcium has an average rating of 6.5 out of 10 from a total of 261 ratings on Drugs.com. 48% of reviewers reported a positive effect, while 23% reported a negative effect.

Mirena has an average rating of 6.1 out of 10 from a total of 2624 ratings on Drugs.com. 46% of reviewers reported a positive effect, while 32% reported a negative effect.

Nexplanon has an average rating of 5.0 out of 10 from a total of 4865 ratings on Drugs.com. 32% of reviewers reported a positive effect, while 43% reported a negative effect.

View all 261 reviews

View all 2624 reviews

View all 4865 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

View all Drospirenone / ethinyl estradiol / levomefolate calcium side effects

View all Mirena side effects

View all Nexplanon side effects
Drug Class
Generic Availability

Lower cost generic

No lower cost generic approved

No lower cost generic approved
Pricing and Coupons * Prices are without insurance
Quantity 84 each
Strength 3 mg-0.02 mg-0.451 mg
Per unit* $1.88
Cost* $158.26

View all Drospirenone / ethinyl estradiol / levomefolate calcium prices

Quantity 1 device
Strength 52 mg
Per unit* $1,306.65
Cost* $1,306.65

View all Mirena prices

Quantity 1 implant
Strength 68 mg
Per unit* $1,306.65
Cost* $1,306.65

View all Nexplanon prices

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Dosage Forms
  • Oral tablet
  • Intrauterine device
  • Subcutaneous implant
Brand Names
Beyaz, Safyral, Tydemy Other levonorgestrel brands include: Aftera, AfterPill, AfterPlan, Athentia Next, Curae, EContra One-Step, Fallback Solo, Her Style, Julie, Kyleena, Liletta, Morning After, My Choice, My Way, New Day, Next Choice One Dose, Opcicon One-Step, Option 2, Optionelle, Plan B One-Step, PostDay One-Step, SheWise, Skyla, Take Action View more

N/A
Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

30 hours

45 hours

25 hours
CSA Schedule 1 View glossary of CSA terms
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
Pregnancy Category
X
Category X Not for use in pregnancy

See the full pregnancy warnings document.
X
Category X Not for use in pregnancy

See the full pregnancy warnings document.
X
Category X Not for use in pregnancy

See the full pregnancy warnings document.
Drug Interactions

A total of 601 drugs are known to interact with Drospirenone / ethinyl estradiol / levomefolate calcium:

  • 96 major drug interactions (240 brand and generic names)
  • 460 moderate drug interactions (1928 brand and generic names)
  • 45 minor drug interactions (515 brand and generic names)

A total of 261 drugs are known to interact with Mirena:

  • 60 major drug interactions (162 brand and generic names)
  • 187 moderate drug interactions (643 brand and generic names)
  • 14 minor drug interactions (65 brand and generic names)

A total of 250 drugs are known to interact with Nexplanon:

  • 61 major drug interactions (165 brand and generic names)
  • 180 moderate drug interactions (595 brand and generic names)
  • 9 minor drug interactions (49 brand and generic names)
Alcohol/Food/Lifestyle Interactions
  • Grapefruit juice may increase the blood levels of certain medications such as drospirenone. You... View more
  • Grapefruit juice may increase the blood levels of certain medications such as levonorgestrel. You... View more
  • Grapefruit juice may increase the blood levels of certain medications such as etonogestrel. You... View more
Disease Interactions
First Approval Date

September 24, 2010

N/A

July 17, 2006
WADA Class View classifications

N/A

N/A

N/A
More Information
Patient Resources
Professional Resources
Related Treatment Guide

1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

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