Diphenhydramine / ibuprofen Alternatives Compared
| Diphenhydramine / ibuprofen | Trazodone | Zolpidem |
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| Diphenhydramine / ibuprofen | Trazodone | Zolpidem |
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Over-the-counter
Prescribed for Insomnia, Pain. Diphenhydramine / ibuprofen may also be used for purposes not listed in this medication guide. |
Prescription only
Trazodone is mostly used for its sleep-inducing effects (an off-label indication) rather than as an antidepressant. Only generic forms are available which makes it a lot cheaper than some other... View more |
Prescription only
Zolpidem induces sleep; however, longer-acting formulations may impair physical and mental capabilities the next day. May induce complex or dangerous sleep-related behaviors like "sleep-driving"... View more |
Related suggestions Insomnia
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| More about Diphenhydramine / ibuprofen | More about Trazodone | More about Zolpidem | ||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||
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Diphenhydramine / ibuprofen has an average rating of 7.1 out of 10 from a total of 23 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 17% reported a negative effect. |
Trazodone has an average rating of 6.3 out of 10 from a total of 1439 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 31% reported a negative effect. |
Zolpidem has an average rating of 6.9 out of 10 from a total of 1061 ratings on Drugs.com. 59% of reviewers reported a positive effect, while 22% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||
View all Trazodone side effects |
View all Zolpidem side effects |
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| Drug Class | ||||||||||||||||||
| Generic Availability | ||||||||||||||||||
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N/A |
Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Trazodone prices |
View all Zolpidem prices |
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| Dosage Forms | ||||||||||||||||||
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N/A |
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| Brand Names | ||||||||||||||||||
| Advil PM, Ibuprofen PM, Motrin PM | Raldesy | Ambien, Ambien CR, Edluar, Zolpimist | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||
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9.3 hours |
7.5 hours |
2.6 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
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| Pregnancy Category | ||||||||||||||||||
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Category N
Not classified
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||
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A total of 759 drugs are known to interact with Diphenhydramine / ibuprofen:
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A total of 675 drugs are known to interact with Trazodone:
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A total of 483 drugs are known to interact with Zolpidem:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||
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| Disease Interactions | ||||||||||||||||||
| First Approval Date | ||||||||||||||||||
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December 21, 2005 |
December 24, 1981 |
December 16, 1992 |
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| WADA Class View classifications | ||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||
| Patient Resources | ||||||||||||||||||
| Professional Resources | ||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Diphenhydramine
Diphenhydramine is an antihistamine used to treat sneezing, runny nose, itching, hives and other ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.