Diphenhydramine / ibuprofen Alternatives Compared
| Diphenhydramine / ibuprofen | Trazodone | Zolpidem |
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| Diphenhydramine / ibuprofen | Trazodone | Zolpidem |
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Over-the-counter
Prescribed for Insomnia, Pain. Diphenhydramine / ibuprofen may also be used for purposes not listed in this medication guide. |
Prescription only
Trazodone is mostly used for its sleep-inducing effects (an off-label indication) rather than as an antidepressant. Only generic forms are available which makes it a lot cheaper than some other... View more |
Prescription only
Zolpidem induces sleep; however, longer-acting formulations may impair physical and mental capabilities the next day. May induce complex or dangerous sleep-related behaviors like "sleep-driving"... View more |
Related suggestions Insomnia
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| More about Diphenhydramine / ibuprofen | More about Trazodone | More about Zolpidem | ||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||
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Diphenhydramine / ibuprofen has an average rating of 7.1 out of 10 from a total of 23 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 17% reported a negative effect. |
Trazodone has an average rating of 6.3 out of 10 from a total of 1441 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 31% reported a negative effect. |
Zolpidem has an average rating of 6.9 out of 10 from a total of 1061 ratings on Drugs.com. 59% of reviewers reported a positive effect, while 22% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||
View all Trazodone side effects |
View all Zolpidem side effects |
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| Drug Class | ||||||||||||||||||
| Generic Availability | ||||||||||||||||||
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N/A |
Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Trazodone prices |
View all Zolpidem prices |
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| Dosage Forms | ||||||||||||||||||
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N/A |
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| Brand Names | ||||||||||||||||||
| Advil PM, Ibuprofen PM, Motrin PM | Raldesy | Ambien, Ambien CR, Edluar, Zolpimist | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||
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9.3 hours |
7.5 hours |
2.6 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
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| Pregnancy Category | ||||||||||||||||||
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Category N
Not classified
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||
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A total of 765 drugs are known to interact with Diphenhydramine / ibuprofen:
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A total of 676 drugs are known to interact with Trazodone:
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A total of 483 drugs are known to interact with Zolpidem:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||
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| Disease Interactions | ||||||||||||||||||
| First Approval Date | ||||||||||||||||||
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December 21, 2005 |
December 24, 1981 |
December 16, 1992 |
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| WADA Class View classifications | ||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||
| Patient Resources | ||||||||||||||||||
| Professional Resources | ||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.