Diphenhydramine / Ibuprofen Dosage

Medically reviewed by Drugs.com. Last updated on Oct 24, 2024.

Applies to the following strengths: 38 mg-200 mg; 25 mg-200 mg

Usual Adult Dose for Insomnia

DiphenhydrAMINE-ibuprofen 38 mg-200 mg oral tablet:
2 tablets orally at bedtime not to exceed 2 tablets daily

DiphenhydrAMINE-ibuprofen 25 mg-200 mg oral capsule:
2 capsules orally at bedtime not to exceed 2 capsules daily

Usual Pediatric Dose for Insomnia

12 yrs or older:

DiphenhydrAMINE-ibuprofen 38 mg-200 mg oral tablet:
2 tablets orally at bedtime not to exceed 2 tablets daily

DiphenhydrAMINE-ibuprofen 25 mg-200 mg oral capsule:
2 capsules orally at bedtime not to exceed 2 capsules daily

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

CONTRAINDICATIONS:

Hypersensitivity to active substances or product ingredients
Unless you have time for a full night's sleep
Right before or after heart surgery
With any other product containing diphenhydramine, even one used on skin
If you have sleeplessness without pain
Children under 12 years

Safety and efficacy have not been established in patients younger than 12 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

Take orally at bedtime; may take with food or milk if stomach upset occurs
Do not exceed recommended dose

General:

This drug is for occasional sleeplessness; patients should be instructed to seek medical advice for sleeplessness that persists.

Patient advice:

Patients should be instructed to read the approved patient labeling.
Patients should be instructed to stop using and speak with their healthcare provider immediately if they experience any signs or symptoms of GI bleeding, heart problems, or stroke.
Patients should be instructed to speak with their healthcare provide if pain gets worse, sleeplessness persists for more than 2 weeks, or any new symptoms appear.
Patients should talk to their health care provider if they are pregnant, planning to become pregnant, or breastfeeding; NSAIDs should not be used at 20 weeks or later in pregnancy unless specifically advised to do so by their health care professional.