Comparing Cymbalta vs Zoloft

For Depression started sweating first few days after starting med, and had weird feelings this med was making it worse. All went away after two weeks and now I am doing well with this med.

For Depression After 2 weeks (60mg/day) I am pleased with this. I had constant dysthymia, black periods lasting a few days, breaking into tears for no reason, not coping, couldn't see a way out, hopelessness. I couldn't tell my partner everything: she needs me to be strong. She knew anyway. The medicine leveled it all out. Only 2 weeks but the depression is gone. I even felt briefly euphoric today. I am easier to be around. Calmer. Negatives: a strange dissociative feeling, sort of out-of-body, as if hearing myself talk slowly, dizziness, an itchy rash on my hand, dry mouth, general tiredness, lethargy in bed in the mornings, no erectile problems, but problem reaching orgasm. If these moderate in time, then my 7/10 score will increase.

For Depression I think zoloft for me is great. The only downfall i have with it was headaches. They started right when I began taking zoloft daily. They were intense and hurt like hell. Lasted about 2 weeks. Then bam they were gone. I took it at night before bed. I thought they made me tired. Since I've been on it , I've lost about 20lbs. I don't have the munchies at all & honestly I have to tell myself to eat because it curbs my appetite. I don't feel bloated like I did on Lexapro that's why I switched. Zoloft really works for me and I'm on a low dose. Headaches suck the first few weeks but what a difference from lexapro. Everyone's different.

For Depression I’ve suffered from longstanding low-level depression ever since I can remember, and have often pondered with the idea of trying an antidepressant even though I stay away from medication as much as I can. Everything has worsened over the last year since my youngest, fittest sister died prematurely of breast cancer with extensive liver metastasis (or whichever came first)…I was with her for the 7 weeks after diagnosis and watched her take her last 2 breaths; this pain has become more intense lately and I would find myself crying like a baby over my little sister… My demented elderly father got a prescription for Zoloft (he must also be depressed because of my sister’s death), but since no one at his home was giving it to him I decided to give it a try! I’ve been taking 25mg (elixir) for 2 weeks and have seen a huge difference in my crying spells; I still think about my little sister, but don’t feel that overwhelming sadness as much… The first week I took the Zoloft at bedtime, but started to notice difficulty falling asleep, so now I take it in the morning…I felt no other side effects! I’m far from being a peppy, energetic person, but at least some of my suffering has been alleviated, and that’s what living is about; who needs to be in constant emotional pain!? Good luck to all!