Comparing Cymbalta vs Zoloft
| Cymbalta Remove Cymbalta from your drug comparison | Zoloft Remove Zoloft from your drug comparison |
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| Cymbalta duloxetine Remove Cymbalta from your drug comparison | Zoloft sertraline Remove Zoloft from your drug comparison | ||||||||||||||||
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Cymbalta has antidepressant, anti-anxiety, and pain-relieving properties; however, it has been associated with a discontinuation syndrome on withdrawal even when tapered. Prescribed for Back Pain... View more |
Zoloft is an effective antidepressant with less potential for drowsiness than many other antidepressants. Prescribed for Panic Disorder, Obsessive Compulsive Disorder, Major Depressive Disorder... View more |
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Prescription only |
Prescription only |
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Ratings & Reviews |
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Drug Class |
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Side Effects |
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See the full Cymbalta side effects document. |
See the full Zoloft side effects document. |
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Pricing and Coupons* Prices are without insurance |
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View all Cymbalta prices and generic prices |
View all Zoloft prices and generic prices |
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Generic Availability |
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Dosage Form(s) Available |
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Brand Names |
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| Other duloxetine brands include: Drizalma Sprinkle, Irenka | Other sertraline brands include: Zercapli | ||||||||||||||||
Half LifeThe half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. |
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17 hours |
66 hours |
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CSA Schedule**View glossary of terms. |
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category |
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Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
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Drug Interactions |
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A total of 565 drugs are known to interact with Cymbalta:
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A total of 624 drugs are known to interact with Zoloft:
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Alcohol/Food/Lifestyle Interactions |
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Disease Interactions |
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First Approval Date |
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N/A |
December 30, 1991 |
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WADA ClassView World Anti-Doping Agency classifications. |
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N/A |
N/A |
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More Information |
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Consumer Resources |
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Professional Resources |
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Related Treatment Guide |
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.