Comparing Cymbalta vs Prozac
| Cymbalta | Prozac |
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| Cymbalta (duloxetine) | Prozac (fluoxetine) |
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Prescription only
Cymbalta has antidepressant, anti-anxiety, and pain-relieving properties; however, it has been associated with a discontinuation syndrome on withdrawal even when tapered. Prescribed for Back Pain... View more |
Prescription only
Prozac may be used for the treatment of depression and other mood disorders. It is more likely to cause insomnia than drowsiness. Prescribed for Anxiety and Stress, Major Depressive Disorder... View more |
Related suggestions Depression
Major Depressive Disorder
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| More about Cymbalta (duloxetine) | More about Prozac (fluoxetine) | ||||||||||||||||
| Generic Status | |||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Cymbalta has an average rating of 6.2 out of 10 from a total of 1816 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 30% reported a negative effect. |
Prozac has an average rating of 7.2 out of 10 from a total of 1163 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 20% reported a negative effect. |
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| Drug Class | |||||||||||||||||
| Side Effects | |||||||||||||||||
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Common side effects include:
See also: Cymbalta side effects in more detail. |
See also: Prozac side effects in more detail. |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Cymbalta prices and generic prices |
View all Prozac prices and generic prices |
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| Dosage Form(s) Available | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Other duloxetine brands include: Drizalma Sprinkle, Irenka |
N/A |
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| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
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17 hours |
210 hours |
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| CSA Schedule ** View glossary of terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 576 drugs are known to interact with Cymbalta:
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A total of 655 drugs are known to interact with Prozac:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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N/A |
December 29, 1987 |
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| WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.