Comparing Compazine vs Zofran
| Compazine (prochlorperazine) | Zofran (ondansetron) |
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|---|
| Compazine (prochlorperazine) | Zofran (ondansetron) |
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|---|---|---|
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Prescription and OTC
Prescribed for Nausea/Vomiting, Anxiety, Psychosis. Compazine may also be used for purposes not listed in this medication guide. |
Prescription only
Zofran is used to prevent nausea and vomiting caused by cancer chemotherapy, radiotherapy, or surgery. It is approved for use in adults and children over the age of 4 and is available as tablets... View more |
Related suggestions Nausea/Vomiting
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| More about Compazine (prochlorperazine) | More about Zofran (ondansetron) | |
| Ratings & Reviews | ||
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Compazine has an average rating of 2.2 out of 10 from a total of 298 ratings on Drugs.com. 11% of reviewers reported a positive effect, while 85% reported a negative effect. |
Zofran has an average rating of 8.0 out of 10 from a total of 273 ratings on Drugs.com. 76% of reviewers reported a positive effect, while 15% reported a negative effect. |
|
| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||
View all Compazine side effects |
View all Zofran side effects |
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| Drug Class | ||
| Generic Availability | ||
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N/A |
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| Pricing and Coupons * Prices are without insurance | ||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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| Dosage Forms | ||
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N/A |
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| Brand Names | ||
| Other prochlorperazine brands include: Compro |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||
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23 hours |
4 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
|
| Pregnancy Category | ||
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Category N
Not classified
See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
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| Drug Interactions | ||
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A total of 686 drugs are known to interact with Compazine:
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A total of 360 drugs are known to interact with Zofran:
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| Alcohol/Food/Lifestyle Interactions | ||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||
| First Approval Date | ||
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October 23, 1956 |
December 31, 1992 |
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| WADA Class View classifications | ||
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N/A |
N/A |
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| More Information | ||
| Patient Resources | ||
| Professional Resources | ||
| Related Treatment Guide | ||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.