Comparing Clonazepam vs Phenobarbital

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Clonazepam	Phenobarbital	Enter another drug to compare

Clonazepam

Phenobarbital

Prescription only

Clonazepam may reduce seizure frequency in specific seizure disorders and can be used short-term for panic disorder, to relieve anxiety, or to sedate. When used long-term it can cause dependence and... View more

Prescription only

Prescribed for Epilepsy, Hyperbilirubinemia, Seizures, Sedation, Insomnia. Phenobarbital may also be used for purposes not listed in this medication guide.

More about Clonazepam

More about Phenobarbital

Ratings & Reviews

Clonazepam has an average rating of 8.2 out of 10 from a total of 2186 ratings on Drugs.com. 78% of reviewers reported a positive effect, while 12% reported a negative effect.

Phenobarbital has an average rating of 9.1 out of 10 from a total of 36 ratings on Drugs.com. 92% of reviewers reported a positive effect, while 6% reported a negative effect.

View all 2186 reviews

View all 36 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

Anxiety (7.1%)
Drowsiness (6.7%)
Withdrawal (6.5%)
Insomnia (4.7%)
Tiredness (3.2%)
Depression (3.2%)
Panic attacks (3.1%)

View all Clonazepam side effects

View all Phenobarbital side effects

Drug Class

Generic Availability

Lower cost generic

Pricing and Coupons * Prices are without insurance

Quantity	10 tablet
Strength	0.5 mg
Per unit^*	$1.04 - $1.22
Cost^*	$10.36 - $12.19

View all Clonazepam prices

Quantity	100 each
Strength	32.4 mg
Per unit^*	$0.30
Cost^*	$29.91

View all Phenobarbital prices

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Dosage Forms

Oral tablet
Oral tablet, disintegrating

Injectable solution
Oral elixir
Oral tablet

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

40 hours

118 hours

CSA Schedule ¹ View glossary of CSA terms

Some potential for abuse

Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.

Some potential for abuse

Pregnancy Category

Category D Positive evidence of risk

See the full pregnancy warnings document.

Category D Positive evidence of risk

See the full pregnancy warnings document.

Drug Interactions

A total of 532 drugs are known to interact with Clonazepam:

30 major drug interactions (155 brand and generic names)
469 moderate drug interactions (1738 brand and generic names)
33 minor drug interactions (210 brand and generic names)

A total of 803 drugs are known to interact with Phenobarbital:

241 major drug interactions (704 brand and generic names)
516 moderate drug interactions (3290 brand and generic names)
46 minor drug interactions (178 brand and generic names)

Alcohol/Food/Lifestyle Interactions

Using clonazePAM together with alcohol can increase nervous system side effects such as dizziness... View more

Ask your doctor before using PHENobarbital together with alcohol, this can add to dizziness... View more

Disease Interactions

First Approval Date

June 04, 1975

N/A

WADA Class View classifications

N/A

More Information

Patient Resources

Clonazepam uses

Phenobarbital uses

Professional Resources

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Comparing Clonazepam vs Phenobarbital

See also:

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Prozac

Botox

Ativan

Paroxetine

Lorazepam

Zoloft

Venlafaxine

Buspirone

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Further information

Comparing Clonazepam vs Phenobarbital

See also:

Further information

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