Comparing Ciprofloxacin vs Trimethoprim

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
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Ciprofloxacin

Trimethoprim

Ciprofloxacin is an effective antibiotic that treats a wide variety of infections; however, it should not be given to children aged less than 18 and in adults, it should be reserved for infections... View more

Prescribed for Urinary Tract Infection, Prevention of Bladder infection, Pneumocystis Pneumonia, Bladder Infection, Otitis Media. trimethoprim may also be used for purposes not listed in this medication guide. View more

Prescription only

Ratings & Reviews

View all 846 reviews

View all 134 reviews

Drug Class

Quinolones

Urinary anti-infectives

Side Effects

Commonly reported side effects include: pyelonephritis, arthralgia, and musculoskeletal signs and symptoms.

See the full ciprofloxacin side effects document.

See the full trimethoprim side effects document.

Pricing and Coupons

* Prices are without insurance

Quantity	1 tablet
Dosage	500 mg
Per Unit^*	$11.09
Cost^*	$11.09

View all ciprofloxacin prices

Quantity	100 tablet
Dosage	100 mg
Per Unit^*	$0.37
Cost^*	$36.86

View all trimethoprim prices

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Generic Availability

Yes (this medicine)

Dosage Form(s) Available

Intravenous solution
Oral powder for reconstitution
Oral tablet
Oral tablet, extended release

Oral tablet

Brand Names

Cipro, Cipro Cystitis Pack, Cipro I.V., Cipro XR Primsol

Half Life

The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

4 hours

14 hours

CSA Schedule**

View glossary of terms.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category C Risk cannot be ruled out

See the full Pregnancy Warnings document.

Category C Risk cannot be ruled out

See the full Pregnancy Warnings document.

Drug Interactions

A total of 613 drugs are known to interact with ciprofloxacin:

146 major drug interactions (620 brand and generic names)
385 moderate drug interactions (2746 brand and generic names)
82 minor drug interactions (222 brand and generic names)

A total of 128 drugs are known to interact with trimethoprim:

56 major drug interactions (246 brand and generic names)
58 moderate drug interactions (181 brand and generic names)
14 minor drug interactions (37 brand and generic names)

Alcohol/Food/Lifestyle Interactions

Do not take ciprofloxacin with dairy products such as milk or yogurt, or with calcium-fortified... View more

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

Disease Interactions

First Approval Date

October 22, 1987

May 30, 1980

WADA Class

View World Anti-Doping Agency classifications.

N/A

More Information

Patient resources

Professional Resources

Related Treatment Guide

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer