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Comparing Carvedilol vs Entresto

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Carvedilol Remove Carvedilol from your drug comparison Entresto Remove Entresto from your drug comparison
View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Carvedilol Remove Carvedilol from your drug comparison Entresto sacubitril / valsartan Remove Entresto from your drug comparison

Carvedilol blocks both alpha and beta receptors to lower blood pressure and improve how the heart pumps blood. It is not usually recommended for people with pre-existing breathing problems.... View more

Entresto is a combination medication containing sacubitril and valsartan that may be given to treat heart failure in adults and children over the age of one. Studies have shown it to be superior to... View more

Prescription only

Prescription only

Ratings & Reviews

View all 157 reviews

View all 125 reviews

Drug Class

Side Effects

Commonly reported side effects include: hyperglycemia.

See the full carvedilol side effects document.

Common side effects include: hyperkalemia, hypotension, and increased serum creatinine.

See the full Entresto side effects document.

Pricing and Coupons

* Prices are without insurance
Quantity 100 each
Dosage 25 mg
Per Unit* $0.28 - $0.60
Cost* $28.25 - $59.74

View all carvedilol prices

Quantity 100 each
Dosage 24 mg-26 mg
Per Unit* $8.16
Cost* $815.57

View all Entresto prices

Get free Discount Card

Get free Discount Card

Generic Availability

Yes (this medicine)

No

Dosage Form(s) Available
  • Oral capsule, extended release
  • Oral tablet
  • Oral tablet

Brand Names
Coreg, Coreg CR

N/A

Half Life

The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

3.1 hours

11.5 hours

CSA Schedule**

View glossary of terms.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category
C
Category C Risk cannot be ruled out

See the full Pregnancy Warnings document.

Summary unavailable.

See the full Pregnancy Warnings document.

FDA Alerts

N/A

N/A

Drug Interactions

A total of 509 drugs are known to interact with carvedilol:

  • 45 major drug interactions (207 brand and generic names)
  • 434 moderate drug interactions (2813 brand and generic names)
  • 30 minor drug interactions (206 brand and generic names)

A total of 260 drugs are known to interact with Entresto:

  • 28 major drug interactions (148 brand and generic names)
  • 230 moderate drug interactions (1018 brand and generic names)
  • 2 minor drug interactions (6 brand and generic names)

Alcohol/Food/Lifestyle Interactions
  • Carvedilol and alcohol may have additive effects in lowering your blood pressure. You may... View more
  • If you are taking valsartan you should avoid potassium-containing salt substitutes or... View more

Disease Interactions

First Approval Date

September 14, 1995

July 07, 2015

WADA Class

View World Anti-Doping Agency classifications.

N/A

More Information

Consumer Resources

Professional Resources

Related Treatment Guide

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer