Angiotensin receptor blockers and neprilysin inhibitors
What are Angiotensin receptor blockers and neprilysin inhibitors?
Angiotensin receptor blockers with neprilysin inhibitors is a combination medicine that contains both an angiotensin receptor blocker and a neprilysin inhibitor.
How they work
Angiotensin receptor blockers (ARBs) inhibit the activation of angiotensin II receptor which causes vasodilation, a reduction of aldosterone production and reduced vasopressin release which results in a reduction in blood pressure.
Neprilysin inhibition causes an increase in levels of natriuretic peptides which is important in maintaining fluid and sodium balance through natriuresis, diuresis and vasodilation which reduces blood pressure and assists heart failure.
What they treat
The combination of angiotensin receptor blockers and neprilysin inhibitors are used to reduce risk of complications of heart failure with reduced ejection fraction.
List of Angiotensin receptor blockers and neprilysin inhibitors
|Drug Name||Avg. Rating||Reviews|
Generic name: sacubitril / valsartan
|For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).|
Medical conditions associated with angiotensin receptor blockers and neprilysin inhibitors:
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