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Comparing Caplyta vs Risperdal

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
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Caplyta lumateperone

Risperdal risperidone

Caplyta is an atypical antipsychotic that may be used to treat adults with schizophrenia. Sedation is the most common side effect and it should not be used in people with moderate to severe liver... View more

Risperdal is an antipsychotic that relieves psychotic symptoms in people with schizophrenia or mania and is also used in the treatment of autistic disorder. Side effects are less likely at lower... View more

Prescription only

Ratings & Reviews

View all 27 reviews

View all 195 reviews

Drug Class

Atypical antipsychotics

Atypical antipsychotics

Side Effects

See the full Caplyta side effects document.

Common side effects include: agitation, akathisia, anxiety, constipation, dizziness, drowsiness, dystonia, extrapyramidal reaction, nausea, rhinitis, and weight gain.

See the full Risperdal side effects document.

Pricing and Coupons

* Prices are without insurance

Quantity	30 each
Dosage	42 mg
Per Unit^*	$49.01
Cost^*	$1,470.26

View all Caplyta prices

Quantity	30 tablet
Dosage	0.5 mg
Per Unit^*	$6.23
Cost^*	$186.93

View all Risperdal prices and generic prices

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Generic Availability

Yes

Dosage Form(s) Available

Oral capsule

Oral solution
Oral tablet

Brand Names

N/A

Other risperidone brands include: Perseris, Risperdal Consta

Half Life

The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

18 hours

24 hours

CSA Schedule**

View glossary of terms.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Summary unavailable.

See the full Pregnancy Warnings document.

Category C Risk cannot be ruled out

See the full Pregnancy Warnings document.

FDA Alerts

N/A

FDA Alerts (7)

Drug Interactions

A total of 543 drugs are known to interact with Caplyta:

137 major drug interactions (546 brand and generic names)
405 moderate drug interactions (1581 brand and generic names)
1 minor drug interactions (3 brand and generic names)

A total of 630 drugs are known to interact with Risperdal:

88 major drug interactions (334 brand and generic names)
536 moderate drug interactions (2146 brand and generic names)
6 minor drug interactions (44 brand and generic names)

Alcohol/Food/Lifestyle Interactions

Grapefruit and grapefruit juice may increase the blood levels of lumateperone. In some cases, this... View more
Using lumateperone together with alcohol may increase side effects such as dizziness, drowsiness,... View more

RisperiDONE oral solution should not be mixed with tea or cola. It may be taken with water,... View more

Disease Interactions

First Approval Date

December 20, 2019

December 29, 1993

WADA Class

View World Anti-Doping Agency classifications.

N/A

More Information

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer