Comparing Caplyta vs Depakote
| Caplyta (lumateperone) | Depakote (divalproex sodium) |
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| Caplyta (lumateperone) | Depakote (divalproex sodium) |
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Prescription only
Caplyta is an atypical antipsychotic that is used to treat adults with schizophrenia or depression associated with bipolar disorder. Sleepiness is the most common side effect and it should not be... View more |
Prescription only
Valproic acid treats bipolar manic episodes, various seizure types (partial, absence seizures), and prevents migraines (not acute headaches). Common side effects include gastrointestinal issues... View more |
Related suggestions Bipolar Disorder
Popular comparisons
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| More about Caplyta (lumateperone) | More about Depakote (divalproex sodium) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Caplyta has an average rating of 6.7 out of 10 from a total of 192 ratings on Drugs.com. 56% of reviewers reported a positive effect, while 28% reported a negative effect. |
Depakote has an average rating of 6.4 out of 10 from a total of 333 ratings on Drugs.com. 49% of reviewers reported a positive effect, while 26% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Caplyta side effects |
View all Depakote side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Caplyta prices |
View all Depakote prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
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N/A |
Other divalproex sodium brands include: Depakote ER, Depakote Sprinkles | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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18 hours |
16 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Summary unavailable. See the full pregnancy warnings document. |
Category D
Positive evidence of risk
When Treating Epilepsy And Manic Episodes Associated With Bipolar Disorder
Category X
Not for use in pregnancy
When Treating Migraine See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 609 drugs are known to interact with Caplyta:
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A total of 425 drugs are known to interact with Depakote:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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December 20, 2019 |
March 10, 1983 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.