Comparing Boniva vs Prolia
| Boniva (ibandronate) | Prolia (denosumab) |
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| Boniva (ibandronate) | Prolia (denosumab) |
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Prescription only
Boniva helps to increase bone mineral density and is given as a tablet once every month or by injection once every three months. Common side effects include gastrointestinal disturbances and back... View more |
Prescription only
Prolia is an injection that can be self-administered once every six months for the treatment of osteoporosis. It has been associated with an increased risk of fractures on discontinuation and... View more |
Related suggestions Osteoporosis
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| More about Boniva (ibandronate) | More about Prolia (denosumab) | ||||||||
| Ratings & Reviews | |||||||||
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Boniva has an average rating of 3.2 out of 10 from a total of 99 ratings on Drugs.com. 17% of reviewers reported a positive effect, while 72% reported a negative effect. |
Prolia has an average rating of 2.9 out of 10 from a total of 375 ratings on Drugs.com. 16% of reviewers reported a positive effect, while 76% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||
View all Boniva side effects |
View all Prolia side effects |
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| Drug Class | |||||||||
| Generic Availability | |||||||||
| Lower cost generic approved |
N/A |
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| Pricing and Coupons * Prices are without insurance | |||||||||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Prolia prices |
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| Dosage Forms | |||||||||
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| Brand Names | |||||||||
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N/A |
Other denosumab brands include: Bomyntra, Conexxence, Jubbonti, Osenvelt, Ospomyv, Stoboclo, Wyost, Xbryk, Xgeva View more | ||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||
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N/A |
609.6 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||
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A total of 181 drugs are known to interact with Boniva:
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A total of 311 drugs are known to interact with Prolia:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||
| First Approval Date | |||||||||
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May 16, 2003 |
June 01, 2010 |
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| WADA Class View classifications | |||||||||
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N/A |
N/A |
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| More Information | |||||||||
| Patient Resources | |||||||||
| Professional Resources | |||||||||
| Related Treatment Guide | |||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.