Activella Alternatives Compared
| Activella (estradiol / norethindrone) | Estradiol | Premarin (conjugated estrogens) |
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| Activella (estradiol / norethindrone) | Estradiol | Premarin (conjugated estrogens) |
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Prescription only
Prescribed for Postmenopausal Symptoms, Atrophic Vaginitis, Atrophic Urethritis, Hypoestrogenism. Activella may also be used for purposes not listed in this medication guide. |
Prescription only
Estradiol is a synthetic form of estrogen that may be given for several different indications, including the relief of menopausal symptoms or low estrogen levels caused by other conditions. Its use... View more |
Prescription only
Prescribed for Atrophic Vaginitis, Atrophic Urethritis, Abnormal Uterine Bleeding, Breast Cancer - Palliative, Hypoestrogenism, Oophorectomy, Osteoporosis, Postmenopausal Symptoms, Primary Ovarian... View more |
Related suggestions Postmenopausal Symptoms
Atrophic Vaginitis
Atrophic Urethritis
Hypoestrogenism
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| More about Activella (estradiol / norethindrone) | More about Estradiol | More about Premarin (conjugated estrogens) | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Activella has an average rating of 6.0 out of 10 from a total of 24 ratings on Drugs.com. 50% of reviewers reported a positive effect, while 38% reported a negative effect. |
Estradiol has an average rating of 5.8 out of 10 from a total of 592 ratings on Drugs.com. 46% of reviewers reported a positive effect, while 37% reported a negative effect. |
Premarin has an average rating of 7.7 out of 10 from a total of 84 ratings on Drugs.com. 70% of reviewers reported a positive effect, while 17% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||||||||||
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View all Activella side effects |
View all Estradiol side effects |
View all Premarin side effects |
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| Generic Availability | ||||||||||||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Activella prices |
View all Estradiol prices |
View all Premarin prices |
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| Dosage Forms | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Other estradiol / norethindrone brands include: Amabelz, CombiPatch, Ena, Etyqa, Lopreeza, Mimvey, Mimvey Lo | Alora, Climara, Delestrogen, Depo-Estradiol, Divigel, Dotti, Elestrin, Estra Pellets, Estrace, Estraderm, Estradiol Patch, Estrogel, Evamist, Femring, Lyllana, Menostar, Minivelle, Vivelle-Dot View more | Other conjugated estrogens brands include: Premarin Intravenous | ||||||||||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||||||||||
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14 hours |
16 hours |
N/A |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 452 drugs are known to interact with Activella:
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A total of 390 drugs are known to interact with Estradiol:
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A total of 355 drugs are known to interact with Premarin:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
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| First Approval Date | ||||||||||||||||||||||||||
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November 18, 1998 |
July 23, 1975 |
May 08, 1942 |
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| WADA Class View classifications | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
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| Related Treatment Guide | ||||||||||||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Premarin
Premarin is used to treat symptoms of menopause such as hot flashes, and vaginal dryness. Learn ...
Estrace
Estrace (estradiol) is used to treat symptoms of menopause such as hot flashes and vaginal dryness ...
Ozempic
Learn about Ozempic (semaglutide) for type 2 diabetes treatment, weight management, cardiovascular ...
Lo Loestrin Fe
Lo Loestrin Fe (ethinyl estradiol and norethindrone acetate) birth control tablets are used to ...
Estradiol Patch
Estradiol Patch is used for atrophic urethritis, atrophic vaginitis, breast cancer, palliative ...
Prempro
Prempro (conjugated estrogens and medroxyprogesterone) is used to treat the symptoms of menopause ...
Conjugated estrogens
Conjugated estrogens is used for abnormal uterine bleeding, atrophic urethritis, atrophic ...
Ethinyl estradiol/norethindrone
Ethinyl estradiol/norethindrone is used for abnormal uterine bleeding, acne, birth control ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.