Activella Alternatives Compared
| Activella (estradiol / norethindrone) | Estradiol | Premarin (conjugated estrogens) |
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| Activella (estradiol / norethindrone) | Estradiol | Premarin (conjugated estrogens) |
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Prescription only
Prescribed for Atrophic Vaginitis, Postmenopausal Symptoms, Hypoestrogenism, Atrophic Urethritis. Activella may also be used for purposes not listed in this medication guide. |
Prescription only
Estradiol is a synthetic form of estrogen that may be given for several different indications, including the relief of menopausal symptoms or low estrogen levels caused by other conditions. Its use... View more |
Prescription only
Prescribed for Atrophic Vaginitis, Atrophic Urethritis, Abnormal Uterine Bleeding, Breast Cancer - Palliative, Hypoestrogenism, Oophorectomy, Osteoporosis, Postmenopausal Symptoms, Primary Ovarian... View more |
Related suggestions Postmenopausal Symptoms
Atrophic Vaginitis
Atrophic Urethritis
Hypoestrogenism
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| More about Activella (estradiol / norethindrone) | More about Estradiol | More about Premarin (conjugated estrogens) | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Activella has an average rating of 5.9 out of 10 from a total of 25 ratings on Drugs.com. 48% of reviewers reported a positive effect, while 40% reported a negative effect. |
Estradiol has an average rating of 5.8 out of 10 from a total of 593 ratings on Drugs.com. 46% of reviewers reported a positive effect, while 37% reported a negative effect. |
Premarin has an average rating of 7.7 out of 10 from a total of 84 ratings on Drugs.com. 70% of reviewers reported a positive effect, while 17% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||||||||||
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View all Activella side effects |
View all Estradiol side effects |
View all Premarin side effects |
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| Generic Availability | ||||||||||||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Activella prices |
View all Estradiol prices |
View all Premarin prices |
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| Dosage Forms | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Other estradiol / norethindrone brands include: Abigale, Abigale Lo, Amabelz, CombiPatch, Ena, Etyqa, Lopreeza, Mimvey, Mimvey Lo View more | Alora, Climara, Delestrogen, Depo-Estradiol, Divigel, Dotti, Elestrin, Estra Pellets, Estrace, Estraderm, Estradiol Patch, Estrogel, Evamist, Femring, Lyllana, Menostar, Minivelle, Vivelle-Dot View more | Other conjugated estrogens brands include: Premarin Intravenous | ||||||||||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||||||||||
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14 hours |
16 hours |
N/A |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 453 drugs are known to interact with Activella:
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A total of 391 drugs are known to interact with Estradiol:
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A total of 356 drugs are known to interact with Premarin:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
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| First Approval Date | ||||||||||||||||||||||||||
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November 18, 1998 |
July 23, 1975 |
May 08, 1942 |
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| WADA Class View classifications | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
| Patient Resources | ||||||||||||||||||||||||||
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| Related Treatment Guide | ||||||||||||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.