Tramadol for Depression User Reviews (Page 5)

• Ale...
• Taken for 10 years or more
• January 3, 2024

"I initially was prescribed Tramadol when I had the shingles. That was 15 years ago. Over time, I noticed that it gave me energy, focus, and well-being. All my blood tests come back with no issues. This, for me, is a miracle medicine. It's 100% effective for my depression. I take 150mg per day. I am in my early 70s and have tried everything else under the sun. It has become so hard to get a prescription. So unfair."

• Sad...
• Taken for 6 months to 1 year
• June 24, 2018

"I have chronic depression and PTSD. I have tried all the SSRIs and SNRIs. I've tried combinations of supplements and checked into magnetic brain stimulation treatments. Nothing worked. I was in a car accident and hurt my back. I was prescribed tramadol and noticed within a couple of days that I felt 'normal', happy, not anxious. So I talked to my doctor, who is willing to continue prescribing it for me. I still have my negative thoughts, but they don't dominate my day, nor disrupt my life. I keep up on my magnesium L-threonate, magnesium glycinate, and L-theanine, which make a big difference. Everyone's body chemistry is different. This drug works for my chemistry. I understand that I will have to take a medication for the rest of my life, but it's a small price to pay. There are days I almost didn't make it through. And I'm fortunate to have found something that works for me."

• baz...
• Taken for 1 to 6 months
• December 30, 2023

"I used Tramadol 200 ER for chronic pain. I also had chronic depression for years, totally resistant to any drug. I quickly noticed that my mental state was much better. I also had nightmares early in the morning every night for years and sleeping disorders with agitation, yelling, etc. I took a second pill at night, and all of this was wiped out overnight! It is a miracle drug."

• Her...
• March 15, 2015

"Don't let your ignorant physician deprive you of this miracle drug for your depression. They are trained to shun anything narcotic, even if it may be beneficial to the patient. If you have chronic depression, you should definitely try two 50 mg Tramadol (my 90 generic pills cost me $3.99 for 90 pills at a discount pharmacy: no insurance needed) on an empty stomach at 7 am and two more in the late afternoon. Between these doses, walk a lot and drink plenty of water. The results may be astonishingly good. It may not work for all, but I bet it will work for most people who experience moderate levels of depression. Read about the side effects and then decide: it is worth a shot. In contrast to Tramadol, expensive antidepressants may be unnecessary."

• Cha...
• Taken for 2 to 5 years
• February 4, 2024

"I've been suffering from depression for 15 years. I've tried every antidepressant possible, but nothing worked. I started taking tramadol for pain and it changed my life: no more depression, insomnia, or anxiety. It is a miracle as some of the reviews say! It can be addictive, but it doesn't matter when it allows me to live a normal life. I take 200mg/day. It has been 3 years and I have never increased the dose."

• Pet...
• Taken for 1 to 6 months
• May 26, 2016

"Wonderful drug for depression with no weight gain. I had been on it for 12 months and then decided to wean off it - after 18 months it came back (I have suffered from depression since I was 6). I have now been back on it for 3 months and feel 'normal' again and motivated. I have never been suicidal, but I do lose interest in everything and lose my creativity. My sex drive at times is non-existent, but I force myself to masturbate (Yes - I am single) because if I don’t masturbate, I get an awful ache in my testis, so masturbating even just twice a day helps. Also, I was told it may prevent prostate cancer. To be honest though, if losing my sex drive is the worst of it, then I don’t care as I’m enjoying life again."

• neo...
• Taken for 2 to 5 years
• April 7, 2015

"Several years ago I was given tramadol for light pain. I have suffered from bipolar depression for about 40 years and have taken every drug made for depression. I get a little relief using fetzima but the cost is prohibitive. After taking the tramadol I realized that my depression and panic attacks just disappeared. In Mississippi it's almost impossible to get tramadol prescribed so I kept my supply by ordering out of the country which is also very expensive. When you are suicidal much of the time you will seek help wherever you can find it. I finally got a nurse practitioner to prescribe me two 50 mg tablets a day. I have a high tolerance to all drugs and four 50 mg gives me total relief from my mental illness. Side effects decreased sex drive."

• mrs...
• December 29, 2015

"I have had major health issues all year: three bulging discs in my neck. I got the pain somewhat masked with multiple rounds of injections and finally burning the nerve endings in my neck, so that I am no longer waking every morning in pain. I subsequently tore a ligament in my shoulder and am now having to start physical therapy and see an orthopedic doctor. I have been taking muscle relaxers as well as hydrocodone. Having constant pain issues for so long has made me feel depressed, all I want to do is work and sleep. Today, I went to my medicine pantry and pulled out a bottle of tramadol that I had been prescribed previously. I took one, and within an hour, the fog lifted, and I feel 100% better! I will be taking this daily now."

• Blu...
• July 3, 2017

"I originally took Tramadol for pain. I previously had bouts with depression, which totally consumed me. I tried Tramadol (50 mg noon time and one at bedtime.) It pulled me out of the depression before it took me over. Works great."

• Try...
• Taken for 1 to 2 years
• June 30, 2019

"I was diagnosed with diabetic neuropathy. I am now 53. The numbness in my legs stopped me from driving. I grew more isolated. My doctor prescribed painkillers, antidepressants, but I kept going down. Then I fell, tore my ACL, and was given tramadol. Yes, it helped with pain. But for the first time in nine years, I was not depressed! Occasionally happy? I thought, what is causing this? Long story short, it was the tramadol working as an antidepressant. It has given me quality of life. And the dependency issues? If dependency means I can experience joy again, using the same daily amount, so be it. It should not be so difficult for doctors to prescribe."

• Jim...
• November 10, 2015

"I found this drug to be very useful for pain. I have Crohn's disease, degenerative disc disease, migraines, bipolar disorder, PTSD, and anxiety disorder. I take tramadol, 3 pills a day, 150 mg total. The only thing I don't like is that when I skip doses, I get awful side effects like a buzzing or vibration in my head. So I am unable to skip days of taking it, or I feel very awful."

• Pix...
• Taken for less than 1 month
• November 18, 2018

"I have been on Suboxone for 2 1/2 years. I've always had issues with depression/anxiety. However, the Suboxone has made my depression/anxiety 1000 times worse, and I have been put on different kinds of SSRI/SNRI medications, nothing has worked. I did some research on Suboxone combined with tramadol, and let me tell you, I was my bubbly self again. I felt amazing for the first time in a long time. The opiate side of tramadol gets blocked by Suboxone, so it's tramadol's anti-depressant component that is working its magic on me. The doctor will not prescribe this to me since I am in addiction treatment, he won't even prescribe me an anti-depressant that matches tramadol's. I have made my situation even worse now since I got to experience tramadol's anti-depressant magic knowing I can't get that medication prescribed. Imagine every waking day in mental misery and someone hands you something that makes it all go away but to be told you will never get it."

• Hik...
• Taken for 6 months to 1 year
• March 16, 2017

"I, as many of you, have struggled with major depression for a long time. For me, it comes and goes - with a terrible onset towards the end of the winter months. I've tried 4 different antidepressants with no success. Actually, Wellbutrin did help - but I ended up being allergic to it. Go figure. I was prescribed Tramadol for pain last year during a hip problem I was having, and wow, did it help my mood. I didn't feel so broken. This year I am suffering from depression again but haven't started on Tramadol yet. I am nervous because of its addictive qualities, but I cannot keep calling out of work and risk losing my job. It is a terrible feeling. All your posts have been very encouraging, so thank you for sharing!"

• Dre...
• October 5, 2016

"So for pain they're just alright, like a 7. They do last longer than other pain pills, but for my depression, I feel like a better, more capable man when I'm on them. When my supply is gone and I can't find a doc or medical help, I become suicidal. With them, I can live a normal or somewhat normal life."

• Mor...
• Taken for 2 to 5 years
• May 25, 2024

"I used to have a wide variety of diagnoses in recent years, but my most recent ones are Borderline Personality Disorder and depressive episodes. I have tried various medications from quetiapine to lamotrigine. SSRIs/SNRIs didn't work for me either. Tramadol is something that I can control and self-regulate. (I had a past opioid addiction, so it is not recommended for anyone with a similar history.)"

• Not...
• October 4, 2015

"Given to me for pain, didn't work for that but it worked great for my restless leg syndrome and my depression. I take 4 at once a day in the afternoon. I never take more than that. I am addicted, tried to stop taking them for 2 weeks and I felt so sick and weak. I also started getting these weird tings in my head, like a rubber band snap sensation. I can't stop taking them. If I do I can't function well."

• Ras...
• Taken for 2 to 5 years
• April 15, 2025

"Like many others, I was prescribed Tramadol for back pain and noticed immediately it elevated my mood. Where I live, Tramadol is an over-the-counter medication. I built up tolerance very quickly and ended up taking 500 mg a day. Although it certainly helped my low mood, taking such a high dose would only lead to dependency, if I wasn't already dependent. I managed to gradually wean myself off it. My low mood has pretty much returned. There is no cure for depression, only treatment that may or may not work. Tramadol is being seriously looked at as a possible treatment for depression in low doses. There is no doubt it has anti-depression qualities, but being a synthetic opioid, it brings other issues. I wish I had been able to stay on it, but it was just swapping one problem for another."

• Car...
• Taken for 10 years or more
• October 11, 2022

"Without tramadol, my treatment-resistant depression would keep me from getting out of bed each day. I'm able to just function - get up, feed, clothe myself, and take care of other normal responsibilities. Besides, when I am not on it, my thoughts are abjectly self-destructive and even suicidal. I have never taken this drug recreationally, never! I need it because all other medications made me feel worse or made me feel like a zombie, spaced out. Nothing else came close to helping me. For the help that it provides, I'd say that it'd be downright cruel to keep this and other drugs (mushrooms) from people who need them for health, not abuse."

• Sun...
• Taken for 2 to 5 years
• May 28, 2021

"This medicine is a miracle. I swear. Low-dose tramadol taken as a regular antidepressant has saved my life. I used to be able to not drive and have almost seizure-like problems. I wasn’t able to go out of my house or do anything. I have major social anxiety as well. This medication changed my life!!!! I mean it! I have tried every single antidepressant out there, and they all make me ill. Like a zombie. They make me sad. And if you miss a dose, watch out. I was on tramadol for 2 years, and when I got off of it, I had zero issues as well. I was on Xanax for a couple of years a while ago, and it’s what ruined me. Tramadol saved my life. Please look more into this! I’m so healthy because of this medication."

• Dal...
• Taken for less than 1 month
• June 9, 2017

"I have treatment-resistant major depression, and as a result, I've taken so many drugs over the years that I can't list them all. I got kidney stones a while back and got tramadol to help me with the pain. It didn't help much for that, but it sure helped treat my depression. I talked with my primary care doctor about this, and she's reluctant to prescribe it if it isn't for pain. As a result, I'm going to find a new doctor... one who knows a bit more about psychiatry."

• Mar...
• Taken for 2 to 5 years
• July 1, 2019

"Peripheral neuropathy slowly but surely stole my mobility. With that came a loss of social contact and a depression that I had never experienced before. I tried therapy, B12, exercise, health foods, and supplements. Still, I woke up every day with the same goals and hopes as always, but a body that was fading. Maybe tramadol does not bring back mobility. But the energy level increase and the relief from sadness works like nothing else. My neurologist approves. She has seen me function with and without it. I am grateful she prescribes for me to have some quality of life. I know some physicians won't."

• Har...
• Taken for 1 to 6 months
• May 19, 2015

"Tramadol is about the most effective drug in the world for depression - for immediate, short-term relief ONLY though. During the initial dosing period, 100 mg twice a day utterly obliterates any negative thinking or depression symptoms. It delivers results immediately, vs. the necessary patience of waiting a few days or weeks with traditional SSRI drugs. However, tolerance DOES build to tramadol at a pace far more rapidly than with traditional anti-depressants. I had 2 months of solid relief from 100 mg 2x daily, but by the third month this dose barely made a difference and my mood continued to sink. Instead of upping my dose, I went back on Zoloft, which delivers less immediate, but more consistent long-term results for me."

• Bad...
• Taken for 2 to 5 years
• June 9, 2019

"This wonder drug appears to have some big fans! I don't have too much to add, just a few things: Dependency level: I think about dependency as coffee in my opinion. I usually take one 50 mg pill a day (which seems a fairly common dose for you commenters, with no craving for more than that) - I think I've been a self-medicating kind of guy for most of my life for mild to moderate depression, alcohol mostly. Most mornings with a mild hangover and the depression that came with it. Until I started taking Tramadol for a neck injury that is. Amazing first aid for a hangover and the blues! This fact has been an enabler for drinking too much, but lately I'm using Tramadol to quit drinking and with good results. Sleep super well and wake feeling great!"

• Evi...
• Taken for 1 to 6 months
• May 31, 2015

"If you decide to take this med, or your doctor wants you to, ask for the XR version. It truly is 24 hours of pain relief. I take 100 mg XR every night, and the best part is that you get to wake up mostly pain-free. The mild pain relief all day can be enhanced easily with Tylenol. I have tried muscle relaxers, creams, injections, opiates, and this is the only med to be side-effect-free and mixes well with over-the-counter pain meds to manage. The last thing is the mood elevation that accompanies the XR version, I actually stopped taking my antidepressant. This works better than anything I have ever taken for my depression, though anxiety is not helped that much."

• Ang...
• Taken for 5 to 10 years
• December 21, 2016

"I have manic depression and anxiety disorder, and I also have fibromyalgia and chronic pain. This medicine, and I also take 600 mg of gabapentin, works for me. It also helps with menopause symptoms, but for my depression, it really helps keep me from crying all day and helps me feel better."