Skip to main content

Tramadol for Depression User Reviews (Page 2)

Brand names: Tramadol Hydrochloride ER, ConZip Qdolo

Reviews for Tramadol

Commonly mentioned side effects
  • Bec...
  • December 23, 2019

"I am a single mother of 3 boys, one who has autism, and some days were so hard that I was only just coping. I had anxiety and depression. I was prescribed tramadol for a headache I had, and let's just say in about 40 minutes, I went from feeling anxious, stressed, and angry to happy, energetic, and playing with my children. Complete life changer for me for the better. My quality of life improved along with my family's, as now they have a mother who is happy, patient, and calm. I've been on tramadol for about 7 years with no complications. At most, I have gone up to, on 'bad' days, 800 mg, but now I taper down or have a couple of days break so my tolerance does not build, because obviously like other pills, the withdrawal is awful. But so worth it for me."

10 / 10
Was this helpful?YesNo
110 Report
  • big...
  • Taken for 6 months to 1 year
  • September 11, 2023

"I am 44 years old. Been suffering from bouts of depression since teenage years. Last year (2022) had a house fire and I suffered burns on my arm. My 9-year-old son suffered burns on his leg. He was hospitalized and suffered a low blood sugar crisis and passed away. Physical pain and emotional pain brought on serious depression. I was suicidal. I was prescribed Tramadol for the pain but realized that when I took it, my depression dissolved. I have since been taking 50mg, sometimes 100mg, a day. Tramadol has saved my life."

10 / 10
Was this helpful?YesNo
43 Report
  • Tra...
  • Taken for 2 to 5 years
  • January 31, 2015

"I have been on EVERY antidepressant over 20 years. I was prescribed Tramadol for a toothache. Not much help on the pain, but within an hour, I felt hope, energy, and have been on the same 200mg for 4 years without any problems!!!"

10 / 10
Was this helpful?YesNo
161 Report

Frequently asked questions

  • hap...
  • June 8, 2015

"I think there is a reason the government has made Tramadol a Category C drug...they want people in society to take it but everybody in society just wants to get high. Tramadol is the best DEPRESSION, ANXIETY, MILD PAIN MEDICINE EVER. This actually is better than everything without the high. If you actually wanna be a happy person without being high, this is it. 50 mg am - optional second until the next day. Forget the critics. I would say this is like Adderall, without the hunger side effects, lack of sleep, personality disorder, grumpiness, depression, etc. The best thing about it is the government is only selling it for $4 dollars. You don't even need health insurance."

10 / 10
Was this helpful?YesNo
155 Report
  • Anonymous
  • Taken for 1 to 6 months
  • June 17, 2012

"Have taken Tramadol for depression after being labeled treatment-resistant. I have tried all SSRIs, all SNRIs, and one tricyclic antidepressant and did not respond to any of them. Tramadol is the only medicine to bring depression relief. Scientific research at the University of Cincinnati supports this claim as Tramadol is thought to have SNRI properties and may even help OCD in some. Love it."

10 / 10
Was this helpful?YesNo
188 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
  • Oll...
  • Taken for 1 to 6 months
  • November 28, 2016

"It's by far the most efficient medication for my depression and social anxiety with negligible abuse potential and no side effects. The problem is my psychiatrist refuses to prescribe it to me and even threatened to sue my GP over prescribing it to me for depression. She would rather have me on expensive, inefficient stuff with tons of side effects because of big pharma lobbying and money she gets from it... Sick world we live in."

10 / 10
Was this helpful?YesNo
133 Report
  • Hea...
  • Taken for 1 to 2 years
  • August 29, 2017

"I was put on Tramadol for pain, and a funny thing happened. I noticed I felt more energy and overall well-being. I had felt a bit depressed over the years, and they tried a few meds, but none seemed to work. I had surgery and was given Tramadol. Once the pain was gone, I stopped it and noticed I fell back into my old slump. I was in therapy and tried everything. Years later, I went to Mexico for business and saw Tramadol in the pharmacy. I bought one bottle of 50mg capsules and said, 'Let's try this.' 50mg twice a day. Within 2 weeks, people were commenting I seemed like I was happier. It does not give me a high like hydrocodone and other opiate meds. They need to explore this and stop shooting it down as an antidepressant."

10 / 10
Was this helpful?YesNo
123 Report

More FAQ

  • Mak...
  • Taken for 2 to 5 years
  • May 9, 2017

"Weight loss: I lost 21 lbs in 4 months. Better mood = Less appetite = More exercise. Lost craving for carbs. Instead, crave protein. Hike and swim every other day. Sex drive went down, not to zero though, maybe from 8 to 3 (Male), but feeling so much better overall. Well-being without sex. Weird but possible. Once daily 50 mg. Welcome to the new me. This is the first antidepressant I ever took. In summary, feel happier and lost 21 lbs (from 221 to 200). More productive at work. Self-employed, lost money due to depression. Now much better, back to the rat race and loving it. By the way, Tramadol metabolizes better in some people based on ancestry, so I read. It works for me (Sicilian descent). Note: most doctors are reluctant to prescribe tramadol for depression."

10 / 10
Was this helpful?YesNo
120 Report
  • its...
  • Taken for 2 to 5 years
  • October 31, 2016

"I have been using tramadol for my depression, anxiety, and it has also helped me quit drinking and smoking. This has been a miracle for my mental health wellness. I have tried everything, and nothing works better than tramadol. Plus, it helped me stop drinking, which was huge!"

10 / 10
Was this helpful?YesNo
124 Report
  • out...
  • December 18, 2014

"After hurting my back, hips, and developing sciatica from lifting people in hospitals/nursing homes/rehab/home care, I was given Ultram for the excruciating pain. It worked wonderfully without the dopiness associated with narcotics. I had also suffered from depression since I was a child and had been through numerous meds that didn't work or made my life even worse. Tramadol is the only med that I have taken that has successfully treated both my chronic pain as well as my depression, allowing the sun to shine in my life."

10 / 10
Was this helpful?YesNo
138 Report
  • Jam...
  • January 13, 2020

"I actually found tramadol worked for depression while being treated for pain in the back. I noticed how great I began to feel. No depression and actually felt like myself for the first time in years. So I actually had a long talk with my psychiatrist, and after showing him several articles from various sources, such as the NEJM, and much more, and telling him of my experience using it for pain and how it uplifted me, he finally agreed to it on a trial basis. I haven’t looked back since. Now I still take my other depression meds. The tramadol is an additional drug. Yes, it is addictive, and no, I don’t care. Your body will start showing signs of tolerance, and you may need to adjust your dosage over time. I recommend starting on the lowest dosage that works for this reason. Do not abuse it because it makes you feel high or buzzed. This will increase the quickness in tolerance, and you will eventually run into the ceiling on daily maximum dosage."

9 / 10
Was this helpful?YesNo
85 Report
  • Anonymous
  • Taken for 5 to 10 years
  • May 13, 2014

"My life was gray on everything, my mood was bad, depressed, and emotional about having to sweep my own floor. I talked to my primary care doctor and asked about tramadol, and he said great things. I now take 6 a day and have been a different person. I now have energy, patience, and I'm a better father who plays with his kids again. Saved my life."

10 / 10
Was this helpful?YesNo
140 Report
  • obt...
  • Taken for 1 to 2 years
  • October 6, 2014

"Have taken tramadol in the past. It literally saved my life when I was going through severe depression while slowly recovering from a traumatic injury. My doctor at the time put me on a light dose of tramadol to help with my somber mood. I was alive again. Nowadays, it's virtually impossible to get any doctor to prescribe this. I've tried multiple antidepressants over the last several years and they do nothing for me. Tramadol's the best-for me at least."

10 / 10
Was this helpful?YesNo
137 Report
  • Anonymous
  • Taken for 5 to 10 years
  • September 22, 2012

"I went from one antidepressant to another. SSRIs (multiple), TCAs, SNRIs. Nothing worked and, like others, my moods were up and down the whole time. Twice a day, Tramadol has kept me symptom-free for 5 years now. Amazing."

9 / 10
Was this helpful?YesNo
154 Report
  • skl...
  • March 26, 2016

"I was first prescribed Tramadol as an add-on drug with my Vicodin due to a serious injury in a car accident. I also suffer from depression and acute anxiety most of my life with panic attacks. The Vicodin worked at first and then made me sick. I would vomit from it sometimes, then it quit working. I took the tramadol once a day usually in the morning and stopped after a month or so because I felt it wasn't doing anything. Man, was I wrong. My injuries healed and I stopped the Vicodin. Upon reading more about Tramadol, I discovered it acts as a Serotonin and Norepinephrine reuptake inhibitor. So it acts as an antidepressant as well as a 'semi-opiate.' Tramadol itself is not an opiate. Your body converts it into one, similar to Nucynta. Great drug."

10 / 10
Was this helpful?YesNo
121 Report
  • KIN...
  • Taken for 6 months to 1 year
  • June 22, 2016

"A few years back I developed anxiety and depression. Went on the SSRI and hated it. My dr. Then gave me Tramadol for my back and shoulder pain. But I found that it works better for me for my depression and anxiety. After about 30 minutes from taking the pill I start to feel normal again and level headed."

9 / 10
Was this helpful?YesNo
113 Report
  • SAM...
  • Taken for 1 to 2 years
  • January 16, 2025

"I have been on pages and pages of medication for 30 plus years (plus ketamine/TMS/Biofeedback/Therapy, etc.). The trial periods of a new drug, waiting and hoping to see if it works for months, the letdown that it never worked, the severe withdrawals, the severe side effects, then repeat for 30 years, so sad. Then I was prescribed Tramadol for pain. One hour later it was like I was alive. I have had several doctors tell me that this medication is the only medication that helps many of their patients, but they are afraid to prescribe it. As little as 25mg per day is life-changing for me. I take 50mg 1-2 times a day now. Luckily, I have severe back issues, so I pray that I will be able to have access to this medication. It literally has given me a life."

10 / 10
Was this helpful?YesNo
11 Report
  • Cad...
  • Taken for 1 to 2 years
  • March 29, 2024

"Been suffering with depression here and there since 12th grade. I am 44 now. In 2022, I lost my son and depression set in again. While being treated for pain with tramadol, I realized that I felt happier and my mood tremendously improved. I took to the internet for research and found out that tramadol works for depression. Tramadol has saved my life."

10 / 10
Was this helpful?YesNo
24 Report
  • JYa...
  • Taken for 5 to 10 years
  • October 7, 2019

"I love tramadol. I use it for both mood and pain. I usually take 50mg a day but some days none and some days 100mg. I like it because I take as needed. I've been addicted to opioids but this one is different. It's like a miracle drug for me."

10 / 10
Was this helpful?YesNo
77 Report
  • Jul...
  • Taken for 2 to 5 years
  • October 29, 2018

"I LOVE Tramadol. I'm a stay-at-home mom, and I'm overweight, with a big chest, and my back hurts all the time. Chasing toddlers around and doing housework can be aggravating at times. I've found Tramadol to help with quite a few things: Mood, Motivation, pain, depression. I no longer take Valium and Effexor for my anxiety and depression because Tramadol helps everything in my case! It's a wonder pill for me. I usually take 50mg when I get up, 1 later on in the day, then 1 at night. Sometimes I might take 2 in the morning and then 1 later that evening. But regardless, Tramadol makes me feel normal and able to do my everyday duties without being in a slump. It's a shame it's a narcotic now because doctors are hesitant to prescribe, and you don't get refills, so you have to go every month to your doctor to get it. Hope this helps someone in pain and or depression as I've found it to be of help in both areas!"

10 / 10
Was this helpful?YesNo
85 Report
  • sol...
  • July 17, 2015

"Thumbs up! I was prescribed Tramadol for abdominal pain, and in the process of taking once daily, 50mg, I realized that my energy is boosted, my mood is elevated, and I felt 10 to 15 years younger. I also observed more creativity and a heightened sense of well-being. Must be the serotonin higher levels."

9 / 10
Was this helpful?YesNo
114 Report
  • She...
  • Taken for 1 to 2 years
  • December 21, 2020

"I take tramadol for lower pain, however, I use it mainly for depression and anxiety. It works better than any antidepressant I’ve ever taken. I’m on the 50 mg instant release tablets, and I take it up to 4 times a day. I keep my dose between 100 mg and 200 mg a day. I don’t overtake it, as tolerance builds up quickly. In reference to the people who warned that this drug is very addictive and that it shouldn’t be prescribed for depression because of that, I have to say regular antidepressants are just as bad if you quit taking them (major withdrawals, brain zaps, etc.) ...so prescribing tramadol shouldn’t be any different. This drug has done wonders for me, and I’m so happy I was able to find a doctor who would write it for me."

10 / 10
Was this helpful?YesNo
61 Report
  • Mig...
  • April 15, 2016

"I was facing several months of on and off depression since being forced to move. I had and have no one to communicate with anymore. The loneliness made me realize how empty my life is and see no purpose in anything. I lost all motivation. The greater issue was that I was starting to feel like this every day and started pondering suicide. I decided to try Tramadol since it was available to me. I took 100 mg to test it and I felt normal again (able to feel pleasure and then some). The experience was amazing and it gave my social confidence I was lacking. As the Tramadol wore off, I was able to speak in a debate group without issue (I usually get nervous and lose track) and it was noticed. I all"

10 / 10
Was this helpful?YesNo
109 Report
  • Bob...
  • Taken for 5 to 10 years
  • May 6, 2015

"I've been diagnosed with depression by every doctor I've been in face-to-face contact with. I always try to hide my depression from everyone, even doctors. I would go to the ER about twice a year for anxiety attacks. The doctors in the ER would identify my depression right away even with me trying to hide it. I've taken a handful of antidepressants: Zoloft, Effexor, Wellbutrin, and Paxil. I took Zoloft for 2 years and gained 115 lbs. I got prescribed tramadol for pain, as I would stand all day. Immediately, I did not have the need for Zoloft. I was able to get a better job (still standing all day). I lost 104 lbs (saggy skin now). I take 50mg twice a day. On an empty stomach is best. Just like everyone else, tramadol has given me my life back!"

10 / 10
Was this helpful?YesNo
115 Report
  • Anonymous
  • July 13, 2012

"I experienced only adverse reactions to SSRIs and TCAs, thanks in part to being bipolar, but Tramadol has been a godsend for my depression. I was sick and tired, literally, of trying different medicines only to have my mood get thrown around crazily. Tramadol worked when nothing else could touch the depression. I take it twice daily. Could not live without it. I am so thankful that my psychiatrist is open to new ideas and tried this. I only will encourage others to try this also. Because of the Tramadol, I am now recovered from any form of self-injury - I am free for over 3 years. It works. Simple."

10 / 10
Was this helpful?YesNo
137 Report

See also:

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.